CanIsoNet

Gene Name:

Protein Interaction Network

Interaction losses of dMDT
*only proteins having domain-domain interaction information are taken into consideration
Gene
Name		 # of
Interaction*		 # of Missed
Interaction		 Interaction
Lost		 Domain Int
Lost		 Transcript Name dMDT
AP2A1 17 0 None None AP2A1-008 ENST00000359032
AP2A1 17 17 AP2A1-AP5M1 Adaptin_N(31-589)-Adap_comp_sub AP2A1-004 ENST00000597774
AP2A1 17 17 AP2A1-AP2M1 Adaptin_N(31-589)-Adap_comp_sub AP2A1-004 ENST00000597774
AP2A1 17 17 AP2A1-AP4M1 Adaptin_N(31-589)-Adap_comp_sub AP2A1-004 ENST00000597774
AP2A1 17 17 AP2A1-SGIP1 Adaptin_N(31-589)-Adap_comp_sub AP2A1-004 ENST00000597774
AP2A1 17 17 AP2A1-AP1M1 Adaptin_N(31-589)-Adap_comp_sub AP2A1-004 ENST00000597774
AP2A1 17 17 AP2A1-COPZ2 Adaptin_N(31-589)-Clat_adaptor_s AP2A1-004 ENST00000597774
AP2A1 17 17 AP2A1-COPZ1 Adaptin_N(31-589)-Clat_adaptor_s AP2A1-004 ENST00000597774
AP2A1 17 17 AP2A1-AP2S1 Adaptin_N(31-589)-Clat_adaptor_s AP2A1-004 ENST00000597774
AP2A1 17 17 AP2A1-AP3S1 Adaptin_N(31-589)-Clat_adaptor_s AP2A1-004 ENST00000597774
AP2A1 17 17 AP2A1-AP1S2 Adaptin_N(31-589)-Clat_adaptor_s AP2A1-004 ENST00000597774
AP2A1 17 17 AP2A1-AP1S1 Adaptin_N(31-589)-Clat_adaptor_s AP2A1-004 ENST00000597774
AP2A1 17 17 AP2A1-AP3S2 Adaptin_N(31-589)-Clat_adaptor_s AP2A1-004 ENST00000597774
AP2A1 17 17 AP2A1-AP4B1 Adaptin_N(31-589)-Adaptin_N AP2A1-004 ENST00000597774
AP2A1 17 17 AP2A1-AP1G2 Adaptin_N(31-589)-Adaptin_N AP2A1-004 ENST00000597774
AP2A1 17 17 AP2A1-AP2B1 Adaptin_N(31-589)-Adaptin_N AP2A1-004 ENST00000597774
AP2A1 17 17 AP2A1-AP2A2 Adaptin_N(31-589)-Adaptin_N AP2A1-004 ENST00000597774
AP2A1 17 17 AP2A1-COPB2 Adaptin_N(31-589)-Coatomer_WDAD AP2A1-004 ENST00000597774

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT

*Transcripts of this gene has been found as dMDT in these disease types

Samples showing lost interactions due to MDT switch
Sample ID Disease Gene Name 1 Gene Name 2 Transcript Name dMDT
429f0e9d-c160-4b36-a31b-dab1097c6129 Bladder.Bladder-TCC AP2A1 - AP2A1-008 ENST00000359032
94447759-c20c-49f5-b51f-cbfdea41f2e8 Bladder.Bladder-TCC AP2A1 - AP2A1-008 ENST00000359032
a0091162-1691-4b4c-990f-c58369e09548 Blood.Lymph-BNHL AP2A1 - AP2A1-008 ENST00000359032
0307bd0b-b59a-4996-b89d-612e72652890 Breast.Breast-AdenoCA AP2A1 - AP2A1-008 ENST00000359032
ef37a73c-e0a0-4ff6-83a3-6befcdcb51c6 Breast.Breast-AdenoCA AP2A1 - AP2A1-008 ENST00000359032
c9e3d4c7-862b-4ef2-9a08-216fc44e0bdc CervixUteri.Cervix-SCC AP2A1 - AP2A1-008 ENST00000359032
310820cc-fc05-45c6-8f04-a44db0828686 Colon.ColoRect-AdenoCA AP2A1 - AP2A1-008 ENST00000359032
82bb01e9-a659-417b-b9e8-831a76277a21 Colon.ColoRect-AdenoCA AP2A1 - AP2A1-008 ENST00000359032
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA AP2A1 AP5M1 AP2A1-004 ENST00000597774
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA AP2A1 AP2M1 AP2A1-004 ENST00000597774
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA AP2A1 AP4M1 AP2A1-004 ENST00000597774
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA AP2A1 SGIP1 AP2A1-004 ENST00000597774
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA AP2A1 AP1M1 AP2A1-004 ENST00000597774
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA AP2A1 COPZ2 AP2A1-004 ENST00000597774
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA AP2A1 COPZ1 AP2A1-004 ENST00000597774
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA AP2A1 AP2S1 AP2A1-004 ENST00000597774
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA AP2A1 AP3S1 AP2A1-004 ENST00000597774
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA AP2A1 AP1S2 AP2A1-004 ENST00000597774
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA AP2A1 AP1S1 AP2A1-004 ENST00000597774
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA AP2A1 AP3S2 AP2A1-004 ENST00000597774
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA AP2A1 AP4B1 AP2A1-004 ENST00000597774
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA AP2A1 AP1G2 AP2A1-004 ENST00000597774
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA AP2A1 AP2B1 AP2A1-004 ENST00000597774
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA AP2A1 AP2A2 AP2A1-004 ENST00000597774
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA AP2A1 COPB2 AP2A1-004 ENST00000597774
008292c8-81f5-4930-b179-a198686fc79b Kidney.Kidney-RCC AP2A1 - AP2A1-008 ENST00000359032
22f1d19e-14f8-403e-9e48-663da7508bf2 Kidney.Kidney-RCC AP2A1 - AP2A1-008 ENST00000359032
2fecf6cb-e69b-43f5-b5b4-3f2d32a7ff44 Kidney.Kidney-RCC AP2A1 - AP2A1-008 ENST00000359032
87ddacee-93c2-4a9a-9e53-3af7fe5c0886 Kidney.Kidney-RCC AP2A1 - AP2A1-008 ENST00000359032
b8862635-21cd-405b-b757-8ee924a7a826 Kidney.Kidney-RCC AP2A1 - AP2A1-008 ENST00000359032
bdab7f7f-35cc-4560-a9a0-2263e62afa6c Kidney.Kidney-RCC AP2A1 - AP2A1-008 ENST00000359032
bf7a15fb-0afe-49c9-ae7b-f5fc9f47531f Kidney.Kidney-RCC AP2A1 - AP2A1-008 ENST00000359032
56e6f602-0afb-434e-b28e-665d923ad781 Liver.Liver-HCC AP2A1 - AP2A1-008 ENST00000359032
5bd6ca42-16ca-484f-877f-cda4fb3f93a8 Liver.Liver-HCC AP2A1 - AP2A1-008 ENST00000359032
e642839c-9891-4ff0-93c4-556d81572af9 Liver.Liver-HCC AP2A1 - AP2A1-008 ENST00000359032
15c0fde7-d2b9-434d-81be-196d49244f8d Ovary.Ovary-AdenoCA AP2A1 - AP2A1-008 ENST00000359032
26514a38-7c8b-4afa-9814-e129c58a9120 Ovary.Ovary-AdenoCA AP2A1 - AP2A1-008 ENST00000359032
358984cc-b532-4f00-89f4-dda524469b6d Ovary.Ovary-AdenoCA AP2A1 - AP2A1-008 ENST00000359032
72e75aa6-315d-41dc-a7ea-ff5a20d507a5 Ovary.Ovary-AdenoCA AP2A1 - AP2A1-008 ENST00000359032
4ab212b1-2a55-4850-8610-8a3c96ed0c1b Thyroid.Thy-AdenoCA AP2A1 - AP2A1-008 ENST00000359032
ee665717-a903-44bc-8eaa-afb46bd4edf0 Thyroid.Thy-AdenoCA AP2A1 - AP2A1-008 ENST00000359032
02528092-3a7a-4ddf-8801-e47a48fdeafe Uterus.Uterus-AdenoCA AP2A1 - AP2A1-008 ENST00000359032
2b483617-1fc6-4809-b15c-d48d687ca3b8 Uterus.Uterus-AdenoCA AP2A1 - AP2A1-008 ENST00000359032
2c5d86e0-2e3d-4259-97e9-023df54c8c56 Uterus.Uterus-AdenoCA AP2A1 - AP2A1-008 ENST00000359032
2f712e62-f400-4922-bdc5-d5d06276101d Uterus.Uterus-AdenoCA AP2A1 - AP2A1-008 ENST00000359032
8edc23c4-43f8-4dd3-8c40-257297393492 Uterus.Uterus-AdenoCA AP2A1 - AP2A1-008 ENST00000359032
96756b4d-0e43-404d-a819-dc6da126eef8 Uterus.Uterus-AdenoCA AP2A1 - AP2A1-008 ENST00000359032
c60df680-5bd6-48cc-a112-985f73d9092c Uterus.Uterus-AdenoCA AP2A1 - AP2A1-008 ENST00000359032