CanIsoNet

Gene Name:

Protein Interaction Network

Interaction losses of dMDT
*only proteins having domain-domain interaction information are taken into consideration
Gene
Name		 # of
Interaction*		 # of Missed
Interaction		 Interaction
Lost		 Domain Int
Lost		 Transcript Name dMDT
ARHGEF5 6 0 None None ARHGEF5-002 ENST00000474817
ARHGEF5 6 0 None None ARHGEF5-005 ENST00000471847
ARHGEF5 6 6 ARHGEF5-RAC1 RhoGEF(1180-1356)-Ras ARHGEF5-004 ENST00000498580
ARHGEF5 6 6 ARHGEF5-ARHGAP5 RhoGEF(1180-1356)-Ras ARHGEF5-004 ENST00000498580
ARHGEF5 6 6 ARHGEF5-RHOA RhoGEF(1180-1356)-Ras ARHGEF5-004 ENST00000498580
ARHGEF5 6 6 ARHGEF5-GNA12 RhoGEF(1180-1356)-G-alpha ARHGEF5-004 ENST00000498580
ARHGEF5 6 6 ARHGEF5-GNAQ RhoGEF(1180-1356)-G-alpha ARHGEF5-004 ENST00000498580
ARHGEF5 6 6 ARHGEF5-GNA13 RhoGEF(1180-1356)-G-alpha ARHGEF5-004 ENST00000498580

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT

*Transcripts of this gene has been found as dMDT in these disease types

Samples showing lost interactions due to MDT switch
Sample ID Disease Gene Name 1 Gene Name 2 Transcript Name dMDT
0046fef7-052b-4d4e-b264-b3bf2e2699b1 CervixUteri.Cervix-SCC ARHGEF5 - ARHGEF5-002 ENST00000474817
c9e3d4c7-862b-4ef2-9a08-216fc44e0bdc CervixUteri.Cervix-SCC ARHGEF5 - ARHGEF5-002 ENST00000474817
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA ARHGEF5 - ARHGEF5-005 ENST00000471847
26514a38-7c8b-4afa-9814-e129c58a9120 Ovary.Ovary-AdenoCA ARHGEF5 - ARHGEF5-002 ENST00000474817
358984cc-b532-4f00-89f4-dda524469b6d Ovary.Ovary-AdenoCA ARHGEF5 - ARHGEF5-002 ENST00000474817
689b89a0-a058-44f9-8bca-0b8cb6f6b697 Ovary.Ovary-AdenoCA ARHGEF5 - ARHGEF5-002 ENST00000474817
c38294af-7b80-470a-99eb-523f3fafbbaa Ovary.Ovary-AdenoCA ARHGEF5 - ARHGEF5-002 ENST00000474817
cf1625b4-f30b-487f-8e2c-2866af730c7f Ovary.Ovary-AdenoCA ARHGEF5 - ARHGEF5-002 ENST00000474817
d6aab8b1-8b8b-443f-b2bc-1539c59efe42 Ovary.Ovary-AdenoCA ARHGEF5 - ARHGEF5-002 ENST00000474817
f72b280c-e0d0-4b08-bfe3-cd868a2f1b4c Ovary.Ovary-AdenoCA ARHGEF5 - ARHGEF5-002 ENST00000474817
8027afbd-234f-4911-b193-880741f216d4 Pancreas.Panc-AdenoCA ARHGEF5 RAC1 ARHGEF5-004 ENST00000498580
8027afbd-234f-4911-b193-880741f216d4 Pancreas.Panc-AdenoCA ARHGEF5 ARHGAP5 ARHGEF5-004 ENST00000498580
8027afbd-234f-4911-b193-880741f216d4 Pancreas.Panc-AdenoCA ARHGEF5 RHOA ARHGEF5-004 ENST00000498580
8027afbd-234f-4911-b193-880741f216d4 Pancreas.Panc-AdenoCA ARHGEF5 GNA12 ARHGEF5-004 ENST00000498580
8027afbd-234f-4911-b193-880741f216d4 Pancreas.Panc-AdenoCA ARHGEF5 GNAQ ARHGEF5-004 ENST00000498580
8027afbd-234f-4911-b193-880741f216d4 Pancreas.Panc-AdenoCA ARHGEF5 GNA13 ARHGEF5-004 ENST00000498580
4ab212b1-2a55-4850-8610-8a3c96ed0c1b Thyroid.Thy-AdenoCA ARHGEF5 - ARHGEF5-002 ENST00000474817