CanIsoNet

Gene Name:

Protein Interaction Network

Interaction losses of dMDT
*only proteins having domain-domain interaction information are taken into consideration
Gene
Name		 # of
Interaction*		 # of Missed
Interaction		 Interaction
Lost		 Domain Int
Lost		 Transcript Name dMDT
CNOT2 2 2 CNOT2-CNOT1 NOT2_3_5(395-522)-Not1 CNOT2-013 ENST00000551132
CNOT2 2 2 CNOT2-CNOT3 NOT2_3_5(395-522)-NOT2_3_5 CNOT2-013 ENST00000551132
CNOT2 2 2 CNOT2-CNOT1 NOT2_3_5(395-522)-Not1 CNOT2-027 ENST00000550194
CNOT2 2 2 CNOT2-CNOT3 NOT2_3_5(395-522)-NOT2_3_5 CNOT2-027 ENST00000550194
CNOT2 2 2 CNOT2-CNOT1 NOT2_3_5(395-522)-Not1 CNOT2-040 ENST00000546673
CNOT2 2 2 CNOT2-CNOT3 NOT2_3_5(395-522)-NOT2_3_5 CNOT2-040 ENST00000546673

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT

*Transcripts of this gene has been found as dMDT in these disease types

Samples showing lost interactions due to MDT switch
Sample ID Disease Gene Name 1 Gene Name 2 Transcript Name dMDT
24664b94-f5b5-4a99-a09b-66e23edf5916 Breast.Breast-AdenoCA CNOT2 CNOT1 CNOT2-013 ENST00000551132
24664b94-f5b5-4a99-a09b-66e23edf5916 Breast.Breast-AdenoCA CNOT2 CNOT3 CNOT2-013 ENST00000551132
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA CNOT2 CNOT1 CNOT2-027 ENST00000550194
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA CNOT2 CNOT3 CNOT2-027 ENST00000550194
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA CNOT2 CNOT1 CNOT2-040 ENST00000546673
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA CNOT2 CNOT3 CNOT2-040 ENST00000546673
6ccc37a2-f073-4050-bfcd-de106d86236b Lung.Lung-SCC CNOT2 CNOT1 CNOT2-013 ENST00000551132
6ccc37a2-f073-4050-bfcd-de106d86236b Lung.Lung-SCC CNOT2 CNOT3 CNOT2-013 ENST00000551132
00055bad-54b7-4898-a9ae-3dd8036e62d3 Uterus.Uterus-AdenoCA CNOT2 CNOT1 CNOT2-013 ENST00000551132
00055bad-54b7-4898-a9ae-3dd8036e62d3 Uterus.Uterus-AdenoCA CNOT2 CNOT3 CNOT2-013 ENST00000551132