CanIsoNet

Gene Name:

Protein Interaction Network

Interaction losses of dMDT
*only proteins having domain-domain interaction information are taken into consideration
Gene
Name
# of
Interaction*
# of Missed
Interaction
Interaction
Lost
Domain Int
Lost
Transcript Name dMDT
GPC3 5 0 None None GPC3-201 ENST00000394299
GPC3 5 5 GPC3-GPC1 Glypican(366-600)-Glypican GPC3-202 ENST00000543339
GPC3 5 5 GPC3-GPC2 Glypican(366-600)-Glypican GPC3-202 ENST00000543339
GPC3 5 5 GPC3-GPC4 Glypican(366-600)-Glypican GPC3-202 ENST00000543339
GPC3 5 5 GPC3-GPC6 Glypican(366-600)-Glypican GPC3-202 ENST00000543339
GPC3 5 5 GPC3-GPC5 Glypican(366-600)-Glypican GPC3-202 ENST00000543339

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT

*Transcripts of this gene has been found as dMDT in these disease types

Samples showing lost interactions due to MDT switch
Sample ID Disease Gene Name 1 Gene Name 2 Transcript Name dMDT
0eb9c5a5-1e4e-4808-882e-858b4d0ed396 Breast.Breast-AdenoCA GPC3 - GPC3-201 ENST00000394299
7abad802-817a-4d95-b022-f21cc4b1d9bc Breast.Breast-AdenoCA GPC3 - GPC3-201 ENST00000394299
bd51f90a-ec67-4a7d-87bf-9d85acd65d51 Breast.Breast-AdenoCA GPC3 - GPC3-201 ENST00000394299
f7e26041-2b2f-45ea-8da9-5a0d5bf25781 Breast.Breast-AdenoCA GPC3 - GPC3-201 ENST00000394299
5f8c2272-4530-45b3-a6d7-00de9be46d71 Colon.ColoRect-AdenoCA GPC3 GPC1 GPC3-202 ENST00000543339
5f8c2272-4530-45b3-a6d7-00de9be46d71 Colon.ColoRect-AdenoCA GPC3 GPC2 GPC3-202 ENST00000543339
5f8c2272-4530-45b3-a6d7-00de9be46d71 Colon.ColoRect-AdenoCA GPC3 GPC4 GPC3-202 ENST00000543339
5f8c2272-4530-45b3-a6d7-00de9be46d71 Colon.ColoRect-AdenoCA GPC3 GPC6 GPC3-202 ENST00000543339
5f8c2272-4530-45b3-a6d7-00de9be46d71 Colon.ColoRect-AdenoCA GPC3 GPC5 GPC3-202 ENST00000543339
0c0cfdfb-107b-4a20-bfda-7922453c041e Lung.Lung-AdenoCA GPC3 - GPC3-201 ENST00000394299
33f213fa-6fa4-48ed-bd7e-a63ed8c3a8da Lung.Lung-AdenoCA GPC3 - GPC3-201 ENST00000394299
681fbd5b-5bff-434d-8ff4-d995fc517e93 Lung.Lung-AdenoCA GPC3 - GPC3-201 ENST00000394299
bf920e10-514e-4623-b92e-c83a3e32485f Lung.Lung-AdenoCA GPC3 - GPC3-201 ENST00000394299
d4f590d7-626c-4c70-b170-1ad19d2ff6eb Lung.Lung-AdenoCA GPC3 - GPC3-201 ENST00000394299
16a43a5d-fe72-4b8a-887d-1b40342c1253 Lung.Lung-SCC GPC3 - GPC3-201 ENST00000394299
2b483617-1fc6-4809-b15c-d48d687ca3b8 Uterus.Uterus-AdenoCA GPC3 - GPC3-201 ENST00000394299
484a9564-c6dd-4e54-a319-4d826f308d0c Uterus.Uterus-AdenoCA GPC3 - GPC3-201 ENST00000394299
7348f1f9-8bcf-41e2-bcb0-743823cac926 Uterus.Uterus-AdenoCA GPC3 - GPC3-201 ENST00000394299