CanIsoNet

Gene Name:

Protein Interaction Network

Interaction losses of dMDT
*only proteins having domain-domain interaction information are taken into consideration
Gene
Name		 # of
Interaction*		 # of Missed
Interaction		 Interaction
Lost		 Domain Int
Lost		 Transcript Name dMDT
GRB14 10 0 None None GRB14-001 ENST00000263915
GRB14 10 10 GRB14-INSR SH2(439-520)-fn3 GRB14-005 ENST00000424693
GRB14 10 10 GRB14-TEK SH2(439-520)-fn3 GRB14-005 ENST00000424693
GRB14 10 10 GRB14-PRKCI SH2(439-520)-C1_1 GRB14-005 ENST00000424693
GRB14 10 10 GRB14-PRKCZ SH2(439-520)-C1_1 GRB14-005 ENST00000424693
GRB14 10 10 GRB14-FGFR1 SH2(439-520)-Pkinase_Tyr GRB14-005 ENST00000424693
GRB14 10 10 GRB14-AKT1 PH(237-340)-Pkinase GRB14-005 ENST00000424693
GRB14 10 10 GRB14-PDPK1 PH(237-340)-Pkinase GRB14-005 ENST00000424693
GRB14 10 10 GRB14-SGK1 PH(237-340)-Pkinase GRB14-005 ENST00000424693
GRB14 10 10 GRB14-AKT2 PH(237-340)-Pkinase GRB14-005 ENST00000424693
GRB14 10 10 GRB14-HRAS PH(237-340)-Ras GRB14-005 ENST00000424693
GRB14 10 5 GRB14-INSR SH2(439-520)-fn3 GRB14-002 ENST00000446413
GRB14 10 5 GRB14-TEK SH2(439-520)-fn3 GRB14-002 ENST00000446413
GRB14 10 5 GRB14-PRKCI SH2(439-520)-C1_1 GRB14-002 ENST00000446413
GRB14 10 5 GRB14-PRKCZ SH2(439-520)-C1_1 GRB14-002 ENST00000446413
GRB14 10 5 GRB14-FGFR1 SH2(439-520)-Pkinase_Tyr GRB14-002 ENST00000446413

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT

*Transcripts of this gene has been found as dMDT in these disease types

Samples showing lost interactions due to MDT switch
Sample ID Disease Gene Name 1 Gene Name 2 Transcript Name dMDT
3c79747b-3bd0-4dbe-b3ef-eb89678f0e9b Ovary.Ovary-AdenoCA GRB14 - GRB14-001 ENST00000263915
b7b99c23-fd12-475a-9397-c760e875f441 Ovary.Ovary-AdenoCA GRB14 - GRB14-001 ENST00000263915
d626a136-dcb2-4fdc-a364-c3858cf5173a Pancreas.Panc-AdenoCA GRB14 - GRB14-001 ENST00000263915
861c68b0-8578-4fdc-9423-f6dc856ffe48 Pancreas.Panc-AdenoCA GRB14 INSR GRB14-005 ENST00000424693
861c68b0-8578-4fdc-9423-f6dc856ffe48 Pancreas.Panc-AdenoCA GRB14 TEK GRB14-005 ENST00000424693
861c68b0-8578-4fdc-9423-f6dc856ffe48 Pancreas.Panc-AdenoCA GRB14 PRKCI GRB14-005 ENST00000424693
861c68b0-8578-4fdc-9423-f6dc856ffe48 Pancreas.Panc-AdenoCA GRB14 PRKCZ GRB14-005 ENST00000424693
861c68b0-8578-4fdc-9423-f6dc856ffe48 Pancreas.Panc-AdenoCA GRB14 FGFR1 GRB14-005 ENST00000424693
861c68b0-8578-4fdc-9423-f6dc856ffe48 Pancreas.Panc-AdenoCA GRB14 AKT1 GRB14-005 ENST00000424693
861c68b0-8578-4fdc-9423-f6dc856ffe48 Pancreas.Panc-AdenoCA GRB14 PDPK1 GRB14-005 ENST00000424693
861c68b0-8578-4fdc-9423-f6dc856ffe48 Pancreas.Panc-AdenoCA GRB14 SGK1 GRB14-005 ENST00000424693
861c68b0-8578-4fdc-9423-f6dc856ffe48 Pancreas.Panc-AdenoCA GRB14 AKT2 GRB14-005 ENST00000424693
861c68b0-8578-4fdc-9423-f6dc856ffe48 Pancreas.Panc-AdenoCA GRB14 HRAS GRB14-005 ENST00000424693
78029317-b987-4292-abfe-fe6a1036c805 Pancreas.Panc-AdenoCA GRB14 INSR GRB14-002 ENST00000446413
78029317-b987-4292-abfe-fe6a1036c805 Pancreas.Panc-AdenoCA GRB14 TEK GRB14-002 ENST00000446413
78029317-b987-4292-abfe-fe6a1036c805 Pancreas.Panc-AdenoCA GRB14 PRKCI GRB14-002 ENST00000446413
78029317-b987-4292-abfe-fe6a1036c805 Pancreas.Panc-AdenoCA GRB14 PRKCZ GRB14-002 ENST00000446413
78029317-b987-4292-abfe-fe6a1036c805 Pancreas.Panc-AdenoCA GRB14 FGFR1 GRB14-002 ENST00000446413
14fd82b2-a288-403b-8608-c1d99f602c6f Stomach.Stomach-AdenoCA GRB14 - GRB14-001 ENST00000263915