CanIsoNet

Gene Name:

Protein Interaction Network

Interaction losses of dMDT
*only proteins having domain-domain interaction information are taken into consideration
Gene
Name		 # of
Interaction*		 # of Missed
Interaction		 Interaction
Lost		 Domain Int
Lost		 Transcript Name dMDT
HGF 11 9 HGF-NCK2 Trypsin(501-716)-SH3_1 HGF-003 ENST00000444829
HGF 11 9 HGF-PLCG1 Trypsin(501-716)-SH3_1 HGF-003 ENST00000444829
HGF 11 9 HGF-NCK1 Trypsin(501-716)-SH3_1 HGF-003 ENST00000444829
HGF 11 9 HGF-CRK Trypsin(501-716)-SH3_1 HGF-003 ENST00000444829
HGF 11 9 HGF-GRB2 Trypsin(501-716)-SH3_1 HGF-003 ENST00000444829
HGF 11 9 HGF-CRKL Trypsin(501-716)-SH3_1 HGF-003 ENST00000444829
HGF 11 9 HGF-SRC Trypsin(501-716)-SH3_1 HGF-003 ENST00000444829
HGF 11 9 HGF-BCAR1 Trypsin(501-716)-SH3_1 HGF-003 ENST00000444829
HGF 11 9 HGF-MET Trypsin(501-716)-Sema HGF-003 ENST00000444829
HGF 11 0 None None HGF-005 ENST00000457544

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT

*Transcripts of this gene has been found as dMDT in these disease types

Samples showing lost interactions due to MDT switch
Sample ID Disease Gene Name 1 Gene Name 2 Transcript Name dMDT
526c9170-0f25-4374-9287-1fc40acb6555 Breast.Breast-AdenoCA HGF NCK2 HGF-003 ENST00000444829
526c9170-0f25-4374-9287-1fc40acb6555 Breast.Breast-AdenoCA HGF PLCG1 HGF-003 ENST00000444829
526c9170-0f25-4374-9287-1fc40acb6555 Breast.Breast-AdenoCA HGF NCK1 HGF-003 ENST00000444829
526c9170-0f25-4374-9287-1fc40acb6555 Breast.Breast-AdenoCA HGF CRK HGF-003 ENST00000444829
526c9170-0f25-4374-9287-1fc40acb6555 Breast.Breast-AdenoCA HGF GRB2 HGF-003 ENST00000444829
526c9170-0f25-4374-9287-1fc40acb6555 Breast.Breast-AdenoCA HGF CRKL HGF-003 ENST00000444829
526c9170-0f25-4374-9287-1fc40acb6555 Breast.Breast-AdenoCA HGF SRC HGF-003 ENST00000444829
526c9170-0f25-4374-9287-1fc40acb6555 Breast.Breast-AdenoCA HGF BCAR1 HGF-003 ENST00000444829
526c9170-0f25-4374-9287-1fc40acb6555 Breast.Breast-AdenoCA HGF MET HGF-003 ENST00000444829
53c19904-8698-4eb5-8a80-3c5604dbc109 Pancreas.Panc-AdenoCA HGF - HGF-005 ENST00000457544
ab72ea11-da2d-48a2-9fc2-157d080a67b1 Pancreas.Panc-AdenoCA HGF - HGF-005 ENST00000457544
b0b8a1e4-b23a-4b5a-b6ef-d621cb29a972 Pancreas.Panc-AdenoCA HGF - HGF-005 ENST00000457544
baecf0b1-419c-497b-8e47-f9053f823c58 Pancreas.Panc-AdenoCA HGF - HGF-005 ENST00000457544
cc6baf87-b93e-4648-9584-262daa8bcc21 Pancreas.Panc-AdenoCA HGF - HGF-005 ENST00000457544
dcf64460-46b0-4911-964f-35192194a0cb Pancreas.Panc-AdenoCA HGF - HGF-005 ENST00000457544