CanIsoNet

Gene Name:

Protein Interaction Network

Interaction losses of dMDT
*only proteins having domain-domain interaction information are taken into consideration
Gene
Name		 # of
Interaction*		 # of Missed
Interaction		 Interaction
Lost		 Domain Int
Lost		 Transcript Name dMDT
KLKB1 6 4 KLKB1-SERPING1 Trypsin(391-621)-Serpin KLKB1-002 ENST00000428196
KLKB1 6 4 KLKB1-A2M Trypsin(391-621)-A2M_N KLKB1-002 ENST00000428196
KLKB1 6 4 KLKB1-GP9 Trypsin(391-621)-LRR_8 KLKB1-002 ENST00000428196
KLKB1 6 4 KLKB1-GP1BA Trypsin(391-621)-LRR_8 KLKB1-002 ENST00000428196
KLKB1 6 0 None None KLKB1-008 ENST00000511608
KLKB1 6 4 KLKB1-SERPING1 Trypsin(391-621)-Serpin KLKB1-007 ENST00000513864
KLKB1 6 4 KLKB1-A2M Trypsin(391-621)-A2M_N KLKB1-007 ENST00000513864
KLKB1 6 4 KLKB1-GP9 Trypsin(391-621)-LRR_8 KLKB1-007 ENST00000513864
KLKB1 6 4 KLKB1-GP1BA Trypsin(391-621)-LRR_8 KLKB1-007 ENST00000513864
KLKB1 6 6 KLKB1-F11 PAN_1(292-372)-PAN_1 KLKB1-004 ENST00000446598
KLKB1 6 6 KLKB1-F12 PAN_1(292-372)-Kringle KLKB1-004 ENST00000446598
KLKB1 6 6 KLKB1-SERPING1 Trypsin(391-621)-Serpin KLKB1-004 ENST00000446598
KLKB1 6 6 KLKB1-A2M Trypsin(391-621)-A2M_N KLKB1-004 ENST00000446598
KLKB1 6 6 KLKB1-GP9 Trypsin(391-621)-LRR_8 KLKB1-004 ENST00000446598
KLKB1 6 6 KLKB1-GP1BA Trypsin(391-621)-LRR_8 KLKB1-004 ENST00000446598

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT

*Transcripts of this gene has been found as dMDT in these disease types

Samples showing lost interactions due to MDT switch
Sample ID Disease Gene Name 1 Gene Name 2 Transcript Name dMDT
c9e3d4c7-862b-4ef2-9a08-216fc44e0bdc CervixUteri.Cervix-SCC KLKB1 SERPING1 KLKB1-002 ENST00000428196
c9e3d4c7-862b-4ef2-9a08-216fc44e0bdc CervixUteri.Cervix-SCC KLKB1 A2M KLKB1-002 ENST00000428196
c9e3d4c7-862b-4ef2-9a08-216fc44e0bdc CervixUteri.Cervix-SCC KLKB1 GP9 KLKB1-002 ENST00000428196
c9e3d4c7-862b-4ef2-9a08-216fc44e0bdc CervixUteri.Cervix-SCC KLKB1 GP1BA KLKB1-002 ENST00000428196
87a76195-5000-4976-8a5e-c2875cb9f486 Kidney.Kidney-RCC KLKB1 - KLKB1-008 ENST00000511608
bf7a15fb-0afe-49c9-ae7b-f5fc9f47531f Kidney.Kidney-RCC KLKB1 - KLKB1-008 ENST00000511608
f6c5e9b3-f038-4994-a9f4-f4ccccebd4a7 Kidney.Kidney-RCC KLKB1 - KLKB1-008 ENST00000511608
33fb74dc-e9cf-4cd1-b997-6e1b239fb9e4 Kidney.Kidney-RCC KLKB1 SERPING1 KLKB1-007 ENST00000513864
33fb74dc-e9cf-4cd1-b997-6e1b239fb9e4 Kidney.Kidney-RCC KLKB1 A2M KLKB1-007 ENST00000513864
33fb74dc-e9cf-4cd1-b997-6e1b239fb9e4 Kidney.Kidney-RCC KLKB1 GP9 KLKB1-007 ENST00000513864
33fb74dc-e9cf-4cd1-b997-6e1b239fb9e4 Kidney.Kidney-RCC KLKB1 GP1BA KLKB1-007 ENST00000513864
8fbcec2c-ddb8-11e4-ad8f-5ed8e2d07381 Liver.Biliary-AdenoCA KLKB1 - KLKB1-008 ENST00000511608
108f1509-bd7e-4a10-8989-f20f7b45bb09 Liver.Liver-HCC KLKB1 - KLKB1-008 ENST00000511608
8027afbd-234f-4911-b193-880741f216d4 Pancreas.Panc-AdenoCA KLKB1 F11 KLKB1-004 ENST00000446598
8027afbd-234f-4911-b193-880741f216d4 Pancreas.Panc-AdenoCA KLKB1 F12 KLKB1-004 ENST00000446598
8027afbd-234f-4911-b193-880741f216d4 Pancreas.Panc-AdenoCA KLKB1 SERPING1 KLKB1-004 ENST00000446598
8027afbd-234f-4911-b193-880741f216d4 Pancreas.Panc-AdenoCA KLKB1 A2M KLKB1-004 ENST00000446598
8027afbd-234f-4911-b193-880741f216d4 Pancreas.Panc-AdenoCA KLKB1 GP9 KLKB1-004 ENST00000446598
8027afbd-234f-4911-b193-880741f216d4 Pancreas.Panc-AdenoCA KLKB1 GP1BA KLKB1-004 ENST00000446598
38c3b55f-15e5-4074-8358-b4ca85a5a7fe Pancreas.Panc-AdenoCA KLKB1 SERPING1 KLKB1-007 ENST00000513864
38c3b55f-15e5-4074-8358-b4ca85a5a7fe Pancreas.Panc-AdenoCA KLKB1 A2M KLKB1-007 ENST00000513864
38c3b55f-15e5-4074-8358-b4ca85a5a7fe Pancreas.Panc-AdenoCA KLKB1 GP9 KLKB1-007 ENST00000513864
38c3b55f-15e5-4074-8358-b4ca85a5a7fe Pancreas.Panc-AdenoCA KLKB1 GP1BA KLKB1-007 ENST00000513864