CanIsoNet

Gene Name:

Protein Interaction Network

Interaction losses of dMDT
*only proteins having domain-domain interaction information are taken into consideration
Gene
Name		 # of
Interaction*		 # of Missed
Interaction		 Interaction
Lost		 Domain Int
Lost		 Transcript Name dMDT
LAMB3 11.0 11.0 LAMB3-ITGB4 Laminin_EGF(534-574)-fn3 LAMB3-003 ENST00000415782
LAMB3 11.0 11.0 LAMB3-COL7A1 Laminin_EGF(534-574)-fn3 LAMB3-003 ENST00000415782
LAMB3 11.0 11.0 LAMB3-LAMB1 Laminin_EGF(534-574)-Laminin_EGF LAMB3-003 ENST00000415782
LAMB3 11.0 11.0 LAMB3-LAMA5 Laminin_EGF(534-574)-Laminin_EGF LAMB3-003 ENST00000415782
LAMB3 11.0 11.0 LAMB3-LAMC1 Laminin_EGF(534-574)-Laminin_EGF LAMB3-003 ENST00000415782
LAMB3 11.0 11.0 LAMB3-LAMC2 Laminin_EGF(534-574)-Laminin_EGF LAMB3-003 ENST00000415782
LAMB3 11.0 11.0 LAMB3-LAMB2 Laminin_EGF(534-574)-Laminin_EGF LAMB3-003 ENST00000415782
LAMB3 11.0 11.0 LAMB3-LAMA3 Laminin_EGF(534-574)-Laminin_EGF LAMB3-003 ENST00000415782
LAMB3 11.0 11.0 LAMB3-LAMC3 Laminin_EGF(534-574)-Laminin_EGF LAMB3-003 ENST00000415782
LAMB3 11.0 11.0 LAMB3-AGRN Laminin_EGF(534-574)-Laminin_EGF LAMB3-003 ENST00000415782
LAMB3 11.0 11.0 LAMB3-LAMA2 Laminin_EGF(534-574)-Laminin_EGF LAMB3-003 ENST00000415782
LAMB3 11.0 0.0 None None LAMB3-001 ENST00000356082

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT

*Transcripts of this gene has been found as dMDT in these disease types

Samples showing lost interactions due to MDT switch
Sample ID Disease Gene Name 1 Gene Name 2 Transcript Name dMDT
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA LAMB3 ITGB4 LAMB3-003 ENST00000415782
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA LAMB3 COL7A1 LAMB3-003 ENST00000415782
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA LAMB3 LAMB1 LAMB3-003 ENST00000415782
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA LAMB3 LAMA5 LAMB3-003 ENST00000415782
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA LAMB3 LAMC1 LAMB3-003 ENST00000415782
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA LAMB3 LAMC2 LAMB3-003 ENST00000415782
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA LAMB3 LAMB2 LAMB3-003 ENST00000415782
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA LAMB3 LAMA3 LAMB3-003 ENST00000415782
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA LAMB3 LAMC3 LAMB3-003 ENST00000415782
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA LAMB3 AGRN LAMB3-003 ENST00000415782
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA LAMB3 LAMA2 LAMB3-003 ENST00000415782
SRR19243453 Alzheimer's disease LAMB3 - LAMB3-001 ENST00000356082