CanIsoNet

Gene Name:

Protein Interaction Network

Interaction losses of dMDT
*only proteins having domain-domain interaction information are taken into consideration
Gene
Name		 # of
Interaction*		 # of Missed
Interaction		 Interaction
Lost		 Domain Int
Lost		 Transcript Name dMDT
MCL1 17.0 17.0 MCL1-TNKS Bcl-2(213-312)-Ank MCL1-002 ENST00000307940
MCL1 17.0 17.0 MCL1-BCL2L2 Bcl-2(213-312)-Bcl-2 MCL1-002 ENST00000307940
MCL1 17.0 17.0 MCL1-BCL2A1 Bcl-2(213-312)-Bcl-2 MCL1-002 ENST00000307940
MCL1 17.0 17.0 MCL1-BAX Bcl-2(213-312)-Bcl-2 MCL1-002 ENST00000307940
MCL1 17.0 17.0 MCL1-BCL2L1 Bcl-2(213-312)-Bcl-2 MCL1-002 ENST00000307940
MCL1 17.0 17.0 MCL1-BOK Bcl-2(213-312)-Bcl-2 MCL1-002 ENST00000307940
MCL1 17.0 17.0 MCL1-BCL2 Bcl-2(213-312)-Bcl-2 MCL1-002 ENST00000307940
MCL1 17.0 17.0 MCL1-BAK1 Bcl-2(213-312)-Bcl-2 MCL1-002 ENST00000307940
MCL1 17.0 17.0 MCL1-BCL2L2-PABPN1 Bcl-2(213-312)-Bcl-2 MCL1-002 ENST00000307940
MCL1 17.0 17.0 MCL1-APAF1 Bcl-2(213-312)-CARD MCL1-002 ENST00000307940
MCL1 17.0 17.0 MCL1-TP53 Bcl-2(213-312)-P53 MCL1-002 ENST00000307940
MCL1 17.0 17.0 MCL1-BID Bcl-2(213-312)-BID MCL1-002 ENST00000307940
MCL1 17.0 17.0 MCL1-BCL2L11 Bcl-2(213-312)-Bclx_interact MCL1-002 ENST00000307940
MCL1 17.0 17.0 MCL1-BAD Bcl-2(213-312)-Bcl-2_BAD MCL1-002 ENST00000307940
MCL1 17.0 17.0 MCL1-PMAIP1 Bcl-2(213-312)-PMAIP1 MCL1-002 ENST00000307940
MCL1 17.0 17.0 MCL1-BMF Bcl-2(213-312)-BMF MCL1-002 ENST00000307940
MCL1 17.0 17.0 MCL1-BECN1 Bcl-2(213-312)-BH3 MCL1-002 ENST00000307940
MCL1 17.0 17.0 MCL1-TNKS Bcl-2(213-312)-Ank MCL1-002 ENST00000307940
MCL1 17.0 17.0 MCL1-BCL2L2 Bcl-2(213-312)-Bcl-2 MCL1-002 ENST00000307940
MCL1 17.0 17.0 MCL1-BCL2A1 Bcl-2(213-312)-Bcl-2 MCL1-002 ENST00000307940
MCL1 17.0 17.0 MCL1-BAX Bcl-2(213-312)-Bcl-2 MCL1-002 ENST00000307940
MCL1 17.0 17.0 MCL1-BCL2L1 Bcl-2(213-312)-Bcl-2 MCL1-002 ENST00000307940
MCL1 17.0 17.0 MCL1-BOK Bcl-2(213-312)-Bcl-2 MCL1-002 ENST00000307940
MCL1 17.0 17.0 MCL1-BCL2 Bcl-2(213-312)-Bcl-2 MCL1-002 ENST00000307940
MCL1 17.0 17.0 MCL1-BAK1 Bcl-2(213-312)-Bcl-2 MCL1-002 ENST00000307940
MCL1 17.0 17.0 MCL1-BCL2L2-PABPN1 Bcl-2(213-312)-Bcl-2 MCL1-002 ENST00000307940
MCL1 17.0 17.0 MCL1-APAF1 Bcl-2(213-312)-CARD MCL1-002 ENST00000307940
MCL1 17.0 17.0 MCL1-TP53 Bcl-2(213-312)-P53 MCL1-002 ENST00000307940
MCL1 17.0 17.0 MCL1-BID Bcl-2(213-312)-BID MCL1-002 ENST00000307940
MCL1 17.0 17.0 MCL1-BCL2L11 Bcl-2(213-312)-Bclx_interact MCL1-002 ENST00000307940
MCL1 17.0 17.0 MCL1-BAD Bcl-2(213-312)-Bcl-2_BAD MCL1-002 ENST00000307940
MCL1 17.0 17.0 MCL1-PMAIP1 Bcl-2(213-312)-PMAIP1 MCL1-002 ENST00000307940
MCL1 17.0 17.0 MCL1-BMF Bcl-2(213-312)-BMF MCL1-002 ENST00000307940
MCL1 17.0 17.0 MCL1-BECN1 Bcl-2(213-312)-BH3 MCL1-002 ENST00000307940

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT

*Transcripts of this gene has been found as dMDT in these disease types

Samples showing lost interactions due to MDT switch
Sample ID Disease Gene Name 1 Gene Name 2 Transcript Name dMDT
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA MCL1 TNKS MCL1-002 ENST00000307940
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA MCL1 BCL2L2 MCL1-002 ENST00000307940
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA MCL1 BCL2A1 MCL1-002 ENST00000307940
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA MCL1 BAX MCL1-002 ENST00000307940
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA MCL1 BCL2L1 MCL1-002 ENST00000307940
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA MCL1 BOK MCL1-002 ENST00000307940
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA MCL1 BCL2 MCL1-002 ENST00000307940
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA MCL1 BAK1 MCL1-002 ENST00000307940
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA MCL1 BCL2L2-PABPN1 MCL1-002 ENST00000307940
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA MCL1 APAF1 MCL1-002 ENST00000307940
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA MCL1 TP53 MCL1-002 ENST00000307940
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA MCL1 BID MCL1-002 ENST00000307940
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA MCL1 BCL2L11 MCL1-002 ENST00000307940
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA MCL1 BAD MCL1-002 ENST00000307940
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA MCL1 PMAIP1 MCL1-002 ENST00000307940
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA MCL1 BMF MCL1-002 ENST00000307940
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA MCL1 BECN1 MCL1-002 ENST00000307940
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA MCL1 TNKS MCL1-002 ENST00000307940
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA MCL1 BCL2L2 MCL1-002 ENST00000307940
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA MCL1 BCL2A1 MCL1-002 ENST00000307940
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA MCL1 BAX MCL1-002 ENST00000307940
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA MCL1 BCL2L1 MCL1-002 ENST00000307940
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA MCL1 BOK MCL1-002 ENST00000307940
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA MCL1 BCL2 MCL1-002 ENST00000307940
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA MCL1 BAK1 MCL1-002 ENST00000307940
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA MCL1 BCL2L2-PABPN1 MCL1-002 ENST00000307940
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA MCL1 APAF1 MCL1-002 ENST00000307940
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA MCL1 TP53 MCL1-002 ENST00000307940
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA MCL1 BID MCL1-002 ENST00000307940
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA MCL1 BCL2L11 MCL1-002 ENST00000307940
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA MCL1 BAD MCL1-002 ENST00000307940
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA MCL1 PMAIP1 MCL1-002 ENST00000307940
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA MCL1 BMF MCL1-002 ENST00000307940
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA MCL1 BECN1 MCL1-002 ENST00000307940
SRR19243471 Alzheimer's disease MCL1 TNKS MCL1-002 ENST00000307940
SRR19243471 Alzheimer's disease MCL1 BCL2L2 MCL1-002 ENST00000307940
SRR19243471 Alzheimer's disease MCL1 BCL2A1 MCL1-002 ENST00000307940
SRR19243471 Alzheimer's disease MCL1 BAX MCL1-002 ENST00000307940
SRR19243471 Alzheimer's disease MCL1 BCL2L1 MCL1-002 ENST00000307940
SRR19243471 Alzheimer's disease MCL1 BOK MCL1-002 ENST00000307940
SRR19243471 Alzheimer's disease MCL1 BCL2 MCL1-002 ENST00000307940
SRR19243471 Alzheimer's disease MCL1 BAK1 MCL1-002 ENST00000307940
SRR19243471 Alzheimer's disease MCL1 BCL2L2-PABPN1 MCL1-002 ENST00000307940
SRR19243471 Alzheimer's disease MCL1 APAF1 MCL1-002 ENST00000307940
SRR19243471 Alzheimer's disease MCL1 TP53 MCL1-002 ENST00000307940
SRR19243471 Alzheimer's disease MCL1 BID MCL1-002 ENST00000307940
SRR19243471 Alzheimer's disease MCL1 BCL2L11 MCL1-002 ENST00000307940
SRR19243471 Alzheimer's disease MCL1 BAD MCL1-002 ENST00000307940
SRR19243471 Alzheimer's disease MCL1 PMAIP1 MCL1-002 ENST00000307940
SRR19243471 Alzheimer's disease MCL1 BMF MCL1-002 ENST00000307940
SRR19243471 Alzheimer's disease MCL1 BECN1 MCL1-002 ENST00000307940