CanIsoNet

Gene Name:

Protein Interaction Network

Interaction losses of dMDT
*only proteins having domain-domain interaction information are taken into consideration
Gene
Name		 # of
Interaction*		 # of Missed
Interaction		 Interaction
Lost		 Domain Int
Lost		 Transcript Name dMDT
PRKAR2A 18 18 PRKAR2A-PRKAR2B cNMP_binding(280-372)-cNMP_binding PRKAR2A-004 ENST00000457914
PRKAR2A 18 18 PRKAR2A-PRKAR1A cNMP_binding(280-372)-cNMP_binding PRKAR2A-004 ENST00000457914
PRKAR2A 18 18 PRKAR2A-PRKAR1B cNMP_binding(280-372)-cNMP_binding PRKAR2A-004 ENST00000457914
PRKAR2A 18 18 PRKAR2A-MAPK1 cNMP_binding(280-372)-Pkinase PRKAR2A-004 ENST00000457914
PRKAR2A 18 18 PRKAR2A-PRKX cNMP_binding(280-372)-Pkinase PRKAR2A-004 ENST00000457914
PRKAR2A 18 18 PRKAR2A-PRKCE cNMP_binding(280-372)-Pkinase PRKAR2A-004 ENST00000457914
PRKAR2A 18 18 PRKAR2A-PRKACA cNMP_binding(280-372)-Pkinase PRKAR2A-004 ENST00000457914
PRKAR2A 18 18 PRKAR2A-PKN1 cNMP_binding(280-372)-Pkinase PRKAR2A-004 ENST00000457914
PRKAR2A 18 18 PRKAR2A-PRKACB cNMP_binding(280-372)-Pkinase PRKAR2A-004 ENST00000457914
PRKAR2A 18 18 PRKAR2A-PRKACG cNMP_binding(280-372)-Pkinase PRKAR2A-004 ENST00000457914
PRKAR2A 18 18 PRKAR2A-CDK1 cNMP_binding(280-372)-Pkinase PRKAR2A-004 ENST00000457914
PRKAR2A 18 18 PRKAR2A-KCNS3 cNMP_binding(280-372)-Ion_trans PRKAR2A-004 ENST00000457914
PRKAR2A 18 18 PRKAR2A-KCNG2 cNMP_binding(280-372)-Ion_trans PRKAR2A-004 ENST00000457914
PRKAR2A 18 18 PRKAR2A-KCNB1 cNMP_binding(280-372)-Ion_trans PRKAR2A-004 ENST00000457914
PRKAR2A 18 18 PRKAR2A-KCNC2 cNMP_binding(280-372)-Ion_trans PRKAR2A-004 ENST00000457914
PRKAR2A 18 18 PRKAR2A-SLC9A3R1 RIIa(9-45)-PDZ PRKAR2A-004 ENST00000457914
PRKAR2A 18 18 PRKAR2A-NOS1 RIIa(9-45)-PDZ PRKAR2A-004 ENST00000457914
PRKAR2A 18 18 PRKAR2A-AKAP3 RIIa(9-45)-RII_binding_1 PRKAR2A-004 ENST00000457914

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT

*Transcripts of this gene has been found as dMDT in these disease types

Samples showing lost interactions due to MDT switch
Sample ID Disease Gene Name 1 Gene Name 2 Transcript Name dMDT
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA PRKAR2A PRKAR2B PRKAR2A-004 ENST00000457914
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA PRKAR2A PRKAR1A PRKAR2A-004 ENST00000457914
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA PRKAR2A PRKAR1B PRKAR2A-004 ENST00000457914
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA PRKAR2A MAPK1 PRKAR2A-004 ENST00000457914
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA PRKAR2A PRKX PRKAR2A-004 ENST00000457914
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA PRKAR2A PRKCE PRKAR2A-004 ENST00000457914
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA PRKAR2A PRKACA PRKAR2A-004 ENST00000457914
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA PRKAR2A PKN1 PRKAR2A-004 ENST00000457914
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA PRKAR2A PRKACB PRKAR2A-004 ENST00000457914
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA PRKAR2A PRKACG PRKAR2A-004 ENST00000457914
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA PRKAR2A CDK1 PRKAR2A-004 ENST00000457914
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA PRKAR2A KCNS3 PRKAR2A-004 ENST00000457914
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA PRKAR2A KCNG2 PRKAR2A-004 ENST00000457914
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA PRKAR2A KCNB1 PRKAR2A-004 ENST00000457914
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA PRKAR2A KCNC2 PRKAR2A-004 ENST00000457914
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA PRKAR2A SLC9A3R1 PRKAR2A-004 ENST00000457914
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA PRKAR2A NOS1 PRKAR2A-004 ENST00000457914
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA PRKAR2A AKAP3 PRKAR2A-004 ENST00000457914