Protein Interaction Network
Interaction losses of dMDT
| Gene Name |
# of Interaction* |
# of Missed Interaction |
Interaction Lost |
Domain Int Lost |
Transcript Name | dMDT |
|---|---|---|---|---|---|---|
| PTPN11 | 61.0 | 61.0 | PTPN11-LCP2 | SH2(6-81)-SH2 | PTPN11-004 | ENST00000530818 |
| PTPN11 | 61.0 | 61.0 | PTPN11-CSK | SH2(6-81)-SH2 | PTPN11-004 | ENST00000530818 |
| PTPN11 | 61.0 | 61.0 | PTPN11-STAT3 | SH2(6-81)-SH2 | PTPN11-004 | ENST00000530818 |
| PTPN11 | 61.0 | 61.0 | PTPN11-FER | SH2(6-81)-SH2 | PTPN11-004 | ENST00000530818 |
| PTPN11 | 61.0 | 61.0 | PTPN11-STAT5B | SH2(6-81)-SH2 | PTPN11-004 | ENST00000530818 |
| PTPN11 | 61.0 | 61.0 | PTPN11-CRK | SH2(6-81)-SH2 | PTPN11-004 | ENST00000530818 |
| PTPN11 | 61.0 | 61.0 | PTPN11-STAT2 | SH2(6-81)-SH2 | PTPN11-004 | ENST00000530818 |
| PTPN11 | 61.0 | 61.0 | PTPN11-YES1 | SH2(6-81)-SH2 | PTPN11-004 | ENST00000530818 |
| PTPN11 | 61.0 | 61.0 | PTPN11-SOCS3 | SH2(6-81)-SH2 | PTPN11-004 | ENST00000530818 |
| PTPN11 | 61.0 | 61.0 | PTPN11-LCK | SH2(6-81)-SH2 | PTPN11-004 | ENST00000530818 |
| PTPN11 | 61.0 | 61.0 | PTPN11-GRB2 | SH2(6-81)-SH2 | PTPN11-004 | ENST00000530818 |
| PTPN11 | 61.0 | 61.0 | PTPN11-STAT5A | SH2(6-81)-SH2 | PTPN11-004 | ENST00000530818 |
| PTPN11 | 61.0 | 61.0 | PTPN11-CRKL | SH2(6-81)-SH2 | PTPN11-004 | ENST00000530818 |
| PTPN11 | 61.0 | 61.0 | PTPN11-FYN | SH2(6-81)-SH2 | PTPN11-004 | ENST00000530818 |
| PTPN11 | 61.0 | 61.0 | PTPN11-SRC | SH2(6-81)-SH2 | PTPN11-004 | ENST00000530818 |
| PTPN11 | 61.0 | 61.0 | PTPN11-INPP5D | SH2(6-81)-SH2 | PTPN11-004 | ENST00000530818 |
| PTPN11 | 61.0 | 61.0 | PTPN11-STAT1 | SH2(6-81)-SH2 | PTPN11-004 | ENST00000530818 |
| PTPN11 | 61.0 | 61.0 | PTPN11-SYK | SH2(6-81)-SH2 | PTPN11-004 | ENST00000530818 |
| PTPN11 | 61.0 | 61.0 | PTPN11-HCK | SH2(6-81)-SH2 | PTPN11-004 | ENST00000530818 |
| PTPN11 | 61.0 | 61.0 | PTPN11-JAK2 | SH2(6-81)-SH2 | PTPN11-004 | ENST00000530818 |
| PTPN11 | 61.0 | 61.0 | PTPN11-SHC1 | SH2(6-81)-SH2 | PTPN11-004 | ENST00000530818 |
| PTPN11 | 61.0 | 61.0 | PTPN11-LYN | SH2(6-81)-SH2 | PTPN11-004 | ENST00000530818 |
| PTPN11 | 61.0 | 61.0 | PTPN11-PIK3R2 | SH2(6-81)-SH2 | PTPN11-004 | ENST00000530818 |
| PTPN11 | 61.0 | 61.0 | PTPN11-VAV1 | SH2(6-81)-SH2 | PTPN11-004 | ENST00000530818 |
| PTPN11 | 61.0 | 61.0 | PTPN11-BCAR1 | SH2(6-81)-SH3_1 | PTPN11-004 | ENST00000530818 |
| PTPN11 | 61.0 | 61.0 | PTPN11-GHR | SH2(6-81)-fn3 | PTPN11-004 | ENST00000530818 |
| PTPN11 | 61.0 | 61.0 | PTPN11-IGF1R | SH2(6-81)-fn3 | PTPN11-004 | ENST00000530818 |
| PTPN11 | 61.0 | 61.0 | PTPN11-AXL | SH2(6-81)-fn3 | PTPN11-004 | ENST00000530818 |
| PTPN11 | 61.0 | 61.0 | PTPN11-INSR | SH2(6-81)-fn3 | PTPN11-004 | ENST00000530818 |
| PTPN11 | 61.0 | 61.0 | PTPN11-IL6ST | SH2(6-81)-fn3 | PTPN11-004 | ENST00000530818 |
| PTPN11 | 61.0 | 61.0 | PTPN11-EPHA2 | SH2(6-81)-fn3 | PTPN11-004 | ENST00000530818 |
| PTPN11 | 61.0 | 61.0 | PTPN11-IL2RG | SH2(6-81)-fn3 | PTPN11-004 | ENST00000530818 |
| PTPN11 | 61.0 | 61.0 | PTPN11-TEK | SH2(6-81)-fn3 | PTPN11-004 | ENST00000530818 |
| PTPN11 | 61.0 | 61.0 | PTPN11-CSF2RB | SH2(6-81)-fn3 | PTPN11-004 | ENST00000530818 |
| PTPN11 | 61.0 | 61.0 | PTPN11-DCC | SH2(6-81)-fn3 | PTPN11-004 | ENST00000530818 |
| PTPN11 | 61.0 | 61.0 | PTPN11-PRKCZ | SH2(6-81)-C1_1 | PTPN11-004 | ENST00000530818 |
| PTPN11 | 61.0 | 61.0 | PTPN11-PIK3CA | SH2(6-81)-PI3_PI4_kinase | PTPN11-004 | ENST00000530818 |
| PTPN11 | 61.0 | 61.0 | PTPN11-PIK3CB | SH2(6-81)-PI3_PI4_kinase | PTPN11-004 | ENST00000530818 |
| PTPN11 | 61.0 | 61.0 | PTPN11-PIK3CG | SH2(6-81)-PI3_PI4_kinase | PTPN11-004 | ENST00000530818 |
| PTPN11 | 61.0 | 61.0 | PTPN11-MTOR | SH2(6-81)-PI3_PI4_kinase | PTPN11-004 | ENST00000530818 |
| PTPN11 | 61.0 | 61.0 | PTPN11-PIK3CD | SH2(6-81)-PI3_PI4_kinase | PTPN11-004 | ENST00000530818 |
| PTPN11 | 61.0 | 61.0 | PTPN11-FYB | SH2(6-81)-SH3_2 | PTPN11-004 | ENST00000530818 |
| PTPN11 | 61.0 | 61.0 | PTPN11-FLT3 | SH2(6-81)-Pkinase_Tyr | PTPN11-004 | ENST00000530818 |
| PTPN11 | 61.0 | 61.0 | PTPN11-PDGFRB | SH2(6-81)-Pkinase_Tyr | PTPN11-004 | ENST00000530818 |
| PTPN11 | 61.0 | 61.0 | PTPN11-KDR | SH2(6-81)-Pkinase_Tyr | PTPN11-004 | ENST00000530818 |
| PTPN11 | 61.0 | 61.0 | PTPN11-TYK2 | SH2(6-81)-Pkinase_Tyr | PTPN11-004 | ENST00000530818 |
| PTPN11 | 61.0 | 61.0 | PTPN11-ERBB3 | SH2(6-81)-Pkinase_Tyr | PTPN11-004 | ENST00000530818 |
| PTPN11 | 61.0 | 61.0 | PTPN11-ERBB2 | SH2(6-81)-Pkinase_Tyr | PTPN11-004 | ENST00000530818 |
| PTPN11 | 61.0 | 61.0 | PTPN11-EGFR | SH2(6-81)-Pkinase_Tyr | PTPN11-004 | ENST00000530818 |
| PTPN11 | 61.0 | 61.0 | PTPN11-NTRK2 | SH2(6-81)-Pkinase_Tyr | PTPN11-004 | ENST00000530818 |
| PTPN11 | 61.0 | 61.0 | PTPN11-FLT1 | SH2(6-81)-Pkinase_Tyr | PTPN11-004 | ENST00000530818 |
| PTPN11 | 61.0 | 61.0 | PTPN11-KIT | SH2(6-81)-Pkinase_Tyr | PTPN11-004 | ENST00000530818 |
| PTPN11 | 61.0 | 61.0 | PTPN11-MET | SH2(6-81)-Pkinase_Tyr | PTPN11-004 | ENST00000530818 |
| PTPN11 | 61.0 | 61.0 | PTPN11-TBK1 | SH2(6-81)-Pkinase_Tyr | PTPN11-004 | ENST00000530818 |
| PTPN11 | 61.0 | 61.0 | PTPN11-PTK2B | SH2(6-81)-Pkinase_Tyr | PTPN11-004 | ENST00000530818 |
| PTPN11 | 61.0 | 61.0 | PTPN11-PTK2 | SH2(6-81)-Pkinase_Tyr | PTPN11-004 | ENST00000530818 |
| PTPN11 | 61.0 | 61.0 | PTPN11-JAK1 | SH2(6-81)-Pkinase_Tyr | PTPN11-004 | ENST00000530818 |
| PTPN11 | 61.0 | 61.0 | PTPN11-RET | SH2(6-81)-Pkinase_Tyr | PTPN11-004 | ENST00000530818 |
| PTPN11 | 61.0 | 61.0 | PTPN11-MUSK | SH2(6-81)-Pkinase_Tyr | PTPN11-004 | ENST00000530818 |
| PTPN11 | 61.0 | 61.0 | PTPN11-JAK3 | SH2(6-81)-Pkinase_Tyr | PTPN11-004 | ENST00000530818 |
| PTPN11 | 61.0 | 61.0 | PTPN11-PAG1 | SH2(6-81)-PAG | PTPN11-004 | ENST00000530818 |
| PTPN11 | 61.0 | 0.0 | None | None | PTPN11-002 | ENST00000392597 |
| PTPN11 | 61.0 | 0.0 | None | None | PTPN11-001 | ENST00000351677 |
Network Density Score: %
The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*Transcripts of this gene has been found as dMDT in these disease types
Samples showing lost interactions due to MDT switch