CanIsoNet

Gene Name:

Protein Interaction Network

Interaction losses of dMDT
*only proteins having domain-domain interaction information are taken into consideration
Gene
Name		 # of
Interaction*		 # of Missed
Interaction		 Interaction
Lost		 Domain Int
Lost		 Transcript Name dMDT
SIGIRR 2 0 None None SIGIRR-004 ENST00000431843
SIGIRR 2 0 None None SIGIRR-001 ENST00000332725
SIGIRR 2 0 None None SIGIRR-006 ENST00000397632
SIGIRR 2 2 SIGIRR-TIRAP TIR(167-306)-TIR SIGIRR-023 ENST00000526395
SIGIRR 2 2 SIGIRR-MYD88 TIR(167-306)-TIR SIGIRR-023 ENST00000526395

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT

*Transcripts of this gene has been found as dMDT in these disease types

Samples showing lost interactions due to MDT switch
Sample ID Disease Gene Name 1 Gene Name 2 Transcript Name dMDT
40b5eda3-8b01-4cd7-acb5-0ea4e9ff4312 Brain.CNS-Oligo SIGIRR - SIGIRR-004 ENST00000431843
1f870a12-9d70-4fe4-a176-4cbee06c44e6 CervixUteri.Cervix-SCC SIGIRR - SIGIRR-001 ENST00000332725
5cb8881d-dc6e-4b62-b9a3-d96c83d2567e Kidney.Kidney-ChRCC SIGIRR - SIGIRR-004 ENST00000431843
ee8417b7-5d4b-42e7-b0f1-094a9990fda8 Kidney.Kidney-ChRCC SIGIRR - SIGIRR-004 ENST00000431843
61de326f-12b9-47b4-948e-c84c75e6231f Kidney.Kidney-RCC SIGIRR - SIGIRR-004 ENST00000431843
890fcbee-5720-4a9e-8d71-bb623705e71b Kidney.Kidney-RCC SIGIRR - SIGIRR-004 ENST00000431843
8da87146-a8a4-4b2a-b25d-43cd0ac9d6e4 Kidney.Kidney-RCC SIGIRR - SIGIRR-004 ENST00000431843
cc541704-0f6c-413e-8049-77eaba992844 Kidney.Kidney-RCC SIGIRR - SIGIRR-004 ENST00000431843
04beffef-0cd3-4935-8f2e-9e11c5638973 Liver.Liver-HCC SIGIRR - SIGIRR-001 ENST00000332725
8fb9cfce-ddb8-11e4-ad8f-5ed8e2d07381 Liver.Liver-HCC SIGIRR - SIGIRR-001 ENST00000332725
14fe1014-6e3a-4e94-983a-948140cd2d0d Ovary.Ovary-AdenoCA SIGIRR - SIGIRR-001 ENST00000332725
24985377-300c-4ccb-942c-226e38123b13 Ovary.Ovary-AdenoCA SIGIRR - SIGIRR-001 ENST00000332725
b7b99c23-fd12-475a-9397-c760e875f441 Ovary.Ovary-AdenoCA SIGIRR - SIGIRR-001 ENST00000332725
0ee0c708-77c4-4ac3-be13-0d08e6444003 Ovary.Ovary-AdenoCA SIGIRR - SIGIRR-006 ENST00000397632
5c98c2c5-806f-4562-ad57-e152ea8388ab Ovary.Ovary-AdenoCA SIGIRR - SIGIRR-006 ENST00000397632
7617b0fc-5d98-46f1-af3c-28a8ab6f8c9d Ovary.Ovary-AdenoCA SIGIRR - SIGIRR-006 ENST00000397632
7b412fd9-4414-440f-b768-70666037c768 Ovary.Ovary-AdenoCA SIGIRR - SIGIRR-006 ENST00000397632
83333a5a-de0b-4d72-b886-e5488c619827 Ovary.Ovary-AdenoCA SIGIRR - SIGIRR-006 ENST00000397632
bca48aa6-25bc-49e4-8bb5-edf38362b4a8 Ovary.Ovary-AdenoCA SIGIRR - SIGIRR-006 ENST00000397632
cc5e2498-a9e6-48be-bbda-9aa101546ca4 Ovary.Ovary-AdenoCA SIGIRR - SIGIRR-006 ENST00000397632
d10f0cee-d755-43cc-8d3d-8974cea0defb Ovary.Ovary-AdenoCA SIGIRR - SIGIRR-006 ENST00000397632
eb8cb3b3-d1b1-4d2d-b048-7394931040bd Ovary.Ovary-AdenoCA SIGIRR - SIGIRR-006 ENST00000397632
f4fccaa6-cd8c-4e5a-a7a8-beb63cf7b109 Ovary.Ovary-AdenoCA SIGIRR - SIGIRR-006 ENST00000397632
8027afbd-234f-4911-b193-880741f216d4 Pancreas.Panc-AdenoCA SIGIRR TIRAP SIGIRR-023 ENST00000526395
8027afbd-234f-4911-b193-880741f216d4 Pancreas.Panc-AdenoCA SIGIRR MYD88 SIGIRR-023 ENST00000526395
94a8e647-e53b-4060-81d9-2599c19a05c9 Pancreas.Panc-AdenoCA SIGIRR TIRAP SIGIRR-023 ENST00000526395
94a8e647-e53b-4060-81d9-2599c19a05c9 Pancreas.Panc-AdenoCA SIGIRR MYD88 SIGIRR-023 ENST00000526395
c1620b77-c739-4136-a26c-de1342c11ba7 Pancreas.Panc-AdenoCA SIGIRR TIRAP SIGIRR-023 ENST00000526395
c1620b77-c739-4136-a26c-de1342c11ba7 Pancreas.Panc-AdenoCA SIGIRR MYD88 SIGIRR-023 ENST00000526395
dcdc31de-6cb8-4f41-a3a0-ad1b487709cc Pancreas.Panc-AdenoCA SIGIRR TIRAP SIGIRR-023 ENST00000526395
dcdc31de-6cb8-4f41-a3a0-ad1b487709cc Pancreas.Panc-AdenoCA SIGIRR MYD88 SIGIRR-023 ENST00000526395
0b2aa3d5-f8cd-4047-91cf-295e6b4c8891 Uterus.Uterus-AdenoCA SIGIRR - SIGIRR-006 ENST00000397632
39dbc57b-dd7d-4ebe-a905-47b500adef88 Uterus.Uterus-AdenoCA SIGIRR - SIGIRR-006 ENST00000397632
8e901591-a236-4208-899b-f1bde1e5f841 Uterus.Uterus-AdenoCA SIGIRR - SIGIRR-004 ENST00000431843