CanIsoNet

Gene Name:

Protein Interaction Network

Interaction losses of dMDT
*only proteins having domain-domain interaction information are taken into consideration
Gene
Name		 # of
Interaction*		 # of Missed
Interaction		 Interaction
Lost		 Domain Int
Lost		 Transcript Name dMDT
SKP2 20 0 None None SKP2-001 ENST00000274254
SKP2 20 20 SKP2-NEDD8 F-box-like(97-142)-ubiquitin SKP2-009 ENST00000504386
SKP2 20 20 SKP2-RPS27A F-box-like(97-142)-ubiquitin SKP2-009 ENST00000504386
SKP2 20 20 SKP2-UBB F-box-like(97-142)-ubiquitin SKP2-009 ENST00000504386
SKP2 20 20 SKP2-UBC F-box-like(97-142)-ubiquitin SKP2-009 ENST00000504386
SKP2 20 20 SKP2-UBA52 F-box-like(97-142)-ubiquitin SKP2-009 ENST00000504386
SKP2 20 20 SKP2-ANAPC2 F-box-like(97-142)-Cullin SKP2-009 ENST00000504386
SKP2 20 20 SKP2-CUL1 F-box-like(97-142)-Cullin SKP2-009 ENST00000504386
SKP2 20 20 SKP2-SKP1 F-box-like(97-142)-Skp1 SKP2-009 ENST00000504386
SKP2 20 20 SKP2-FBXO44 F-box-like(97-142)-FBA SKP2-009 ENST00000504386
SKP2 20 20 SKP2-FBXO17 F-box-like(97-142)-FBA SKP2-009 ENST00000504386
SKP2 20 20 SKP2-FBXO27 F-box-like(97-142)-FBA SKP2-009 ENST00000504386
SKP2 20 20 SKP2-FBXO6 F-box-like(97-142)-FBA SKP2-009 ENST00000504386
SKP2 20 20 SKP2-FBXO9 F-box-like(97-142)-F-box-like SKP2-009 ENST00000504386
SKP2 20 20 SKP2-FBXW11 F-box-like(97-142)-F-box-like SKP2-009 ENST00000504386
SKP2 20 20 SKP2-FBXW7 F-box-like(97-142)-F-box-like SKP2-009 ENST00000504386
SKP2 20 20 SKP2-FBXO31 F-box-like(97-142)-F-box-like SKP2-009 ENST00000504386
SKP2 20 20 SKP2-FBXW5 F-box-like(97-142)-F-box-like SKP2-009 ENST00000504386
SKP2 20 20 SKP2-FBXL5 F-box-like(97-142)-F-box-like SKP2-009 ENST00000504386
SKP2 20 20 SKP2-FBXL3 F-box-like(97-142)-F-box-like SKP2-009 ENST00000504386
SKP2 20 20 SKP2-BTRC F-box-like(97-142)-F-box-like SKP2-009 ENST00000504386

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT

*Transcripts of this gene has been found as dMDT in these disease types

Samples showing lost interactions due to MDT switch
Sample ID Disease Gene Name 1 Gene Name 2 Transcript Name dMDT
11436915-2621-4cb8-a5b8-80f221046be9 Blood.Lymph-BNHL SKP2 - SKP2-001 ENST00000274254
2ebb4667-7945-4a92-b620-027b1e8578e4 Blood.Lymph-BNHL SKP2 - SKP2-001 ENST00000274254
5ff2576f-3b08-48f0-8c65-b5f28bc98c89 Blood.Lymph-BNHL SKP2 - SKP2-001 ENST00000274254
01deb3b4-7229-40b1-a567-b1cb80e556eb Ovary.Ovary-AdenoCA SKP2 - SKP2-001 ENST00000274254
24985377-300c-4ccb-942c-226e38123b13 Ovary.Ovary-AdenoCA SKP2 - SKP2-001 ENST00000274254
3c79747b-3bd0-4dbe-b3ef-eb89678f0e9b Ovary.Ovary-AdenoCA SKP2 - SKP2-001 ENST00000274254
44cc1379-e982-4b0d-b2b1-52a0eac6eb20 Ovary.Ovary-AdenoCA SKP2 - SKP2-001 ENST00000274254
689b89a0-a058-44f9-8bca-0b8cb6f6b697 Ovary.Ovary-AdenoCA SKP2 - SKP2-001 ENST00000274254
8d6b2993-255b-4ddb-a324-3d0d7daa87df Ovary.Ovary-AdenoCA SKP2 - SKP2-001 ENST00000274254
94451df0-4a05-4d0a-a0af-f22fd3cc9c38 Ovary.Ovary-AdenoCA SKP2 - SKP2-001 ENST00000274254
9da27735-ffd2-47b7-9ccb-14cebd689495 Ovary.Ovary-AdenoCA SKP2 - SKP2-001 ENST00000274254
a4d107e6-4e56-49e9-8ec8-0903e6f00418 Ovary.Ovary-AdenoCA SKP2 - SKP2-001 ENST00000274254
b7b99c23-fd12-475a-9397-c760e875f441 Ovary.Ovary-AdenoCA SKP2 - SKP2-001 ENST00000274254
c02d7082-de9b-4d72-b457-f1da55aadad8 Ovary.Ovary-AdenoCA SKP2 - SKP2-001 ENST00000274254
c5091a05-88c2-48e5-9680-17c02d27f796 Ovary.Ovary-AdenoCA SKP2 - SKP2-001 ENST00000274254
d3cc0e8f-4fc4-4937-8e40-78bd4cbeb50f Ovary.Ovary-AdenoCA SKP2 - SKP2-001 ENST00000274254
f05dba68-a8a6-4770-9e4d-62d3a9d70a79 Ovary.Ovary-AdenoCA SKP2 - SKP2-001 ENST00000274254
2b483617-1fc6-4809-b15c-d48d687ca3b8 Uterus.Uterus-AdenoCA SKP2 NEDD8 SKP2-009 ENST00000504386
2b483617-1fc6-4809-b15c-d48d687ca3b8 Uterus.Uterus-AdenoCA SKP2 RPS27A SKP2-009 ENST00000504386
2b483617-1fc6-4809-b15c-d48d687ca3b8 Uterus.Uterus-AdenoCA SKP2 UBB SKP2-009 ENST00000504386
2b483617-1fc6-4809-b15c-d48d687ca3b8 Uterus.Uterus-AdenoCA SKP2 UBC SKP2-009 ENST00000504386
2b483617-1fc6-4809-b15c-d48d687ca3b8 Uterus.Uterus-AdenoCA SKP2 UBA52 SKP2-009 ENST00000504386
2b483617-1fc6-4809-b15c-d48d687ca3b8 Uterus.Uterus-AdenoCA SKP2 ANAPC2 SKP2-009 ENST00000504386
2b483617-1fc6-4809-b15c-d48d687ca3b8 Uterus.Uterus-AdenoCA SKP2 CUL1 SKP2-009 ENST00000504386
2b483617-1fc6-4809-b15c-d48d687ca3b8 Uterus.Uterus-AdenoCA SKP2 SKP1 SKP2-009 ENST00000504386
2b483617-1fc6-4809-b15c-d48d687ca3b8 Uterus.Uterus-AdenoCA SKP2 FBXO44 SKP2-009 ENST00000504386
2b483617-1fc6-4809-b15c-d48d687ca3b8 Uterus.Uterus-AdenoCA SKP2 FBXO17 SKP2-009 ENST00000504386
2b483617-1fc6-4809-b15c-d48d687ca3b8 Uterus.Uterus-AdenoCA SKP2 FBXO27 SKP2-009 ENST00000504386
2b483617-1fc6-4809-b15c-d48d687ca3b8 Uterus.Uterus-AdenoCA SKP2 FBXO6 SKP2-009 ENST00000504386
2b483617-1fc6-4809-b15c-d48d687ca3b8 Uterus.Uterus-AdenoCA SKP2 FBXO9 SKP2-009 ENST00000504386
2b483617-1fc6-4809-b15c-d48d687ca3b8 Uterus.Uterus-AdenoCA SKP2 FBXW11 SKP2-009 ENST00000504386
2b483617-1fc6-4809-b15c-d48d687ca3b8 Uterus.Uterus-AdenoCA SKP2 FBXW7 SKP2-009 ENST00000504386
2b483617-1fc6-4809-b15c-d48d687ca3b8 Uterus.Uterus-AdenoCA SKP2 FBXO31 SKP2-009 ENST00000504386
2b483617-1fc6-4809-b15c-d48d687ca3b8 Uterus.Uterus-AdenoCA SKP2 FBXW5 SKP2-009 ENST00000504386
2b483617-1fc6-4809-b15c-d48d687ca3b8 Uterus.Uterus-AdenoCA SKP2 FBXL5 SKP2-009 ENST00000504386
2b483617-1fc6-4809-b15c-d48d687ca3b8 Uterus.Uterus-AdenoCA SKP2 FBXL3 SKP2-009 ENST00000504386
2b483617-1fc6-4809-b15c-d48d687ca3b8 Uterus.Uterus-AdenoCA SKP2 BTRC SKP2-009 ENST00000504386