CanIsoNet

Gene Name:

Protein Interaction Network

Interaction losses of dMDT
*only proteins having domain-domain interaction information are taken into consideration
Gene
Name		 # of
Interaction*		 # of Missed
Interaction		 Interaction
Lost		 Domain Int
Lost		 Transcript Name dMDT
STK11 27 27 STK11-STRADB Pkinase(52-309)-Pkinase STK11-008 ENST00000593219
STK11 27 27 STK11-RPS6KB1 Pkinase(52-309)-Pkinase STK11-008 ENST00000593219
STK11 27 27 STK11-MARK4 Pkinase(52-309)-Pkinase STK11-008 ENST00000593219
STK11 27 27 STK11-SIK1 Pkinase(52-309)-Pkinase STK11-008 ENST00000593219
STK11 27 27 STK11-SIK2 Pkinase(52-309)-Pkinase STK11-008 ENST00000593219
STK11 27 27 STK11-PRKACA Pkinase(52-309)-Pkinase STK11-008 ENST00000593219
STK11 27 27 STK11-BRSK1 Pkinase(52-309)-Pkinase STK11-008 ENST00000593219
STK11 27 27 STK11-BRSK2 Pkinase(52-309)-Pkinase STK11-008 ENST00000593219
STK11 27 27 STK11-STRADA Pkinase(52-309)-Pkinase STK11-008 ENST00000593219
STK11 27 27 STK11-PRKAA1 Pkinase(52-309)-Pkinase STK11-008 ENST00000593219
STK11 27 27 STK11-PRKAA2 Pkinase(52-309)-Pkinase STK11-008 ENST00000593219
STK11 27 27 STK11-MST4 Pkinase(52-309)-Pkinase STK11-008 ENST00000593219
STK11 27 27 STK11-MARK2 Pkinase(52-309)-Pkinase STK11-008 ENST00000593219
STK11 27 27 STK11-KRAS Pkinase(52-309)-Ras STK11-008 ENST00000593219
STK11 27 27 STK11-RAC3 Pkinase(52-309)-Ras STK11-008 ENST00000593219
STK11 27 27 STK11-HRAS Pkinase(52-309)-Ras STK11-008 ENST00000593219
STK11 27 27 STK11-RAC1 Pkinase(52-309)-Ras STK11-008 ENST00000593219
STK11 27 27 STK11-NRAS Pkinase(52-309)-Ras STK11-008 ENST00000593219
STK11 27 27 STK11-IRS1 Pkinase(52-309)-PH STK11-008 ENST00000593219
STK11 27 27 STK11-HSP90AA1 Pkinase(52-309)-HSP90 STK11-008 ENST00000593219
STK11 27 27 STK11-PPM1A Pkinase(52-309)-PP2C STK11-008 ENST00000593219
STK11 27 27 STK11-PTEN Pkinase(52-309)-DSPc STK11-008 ENST00000593219
STK11 27 27 STK11-CDKN1A Pkinase(52-309)-CDI STK11-008 ENST00000593219
STK11 27 27 STK11-CDC37 Pkinase(52-309)-CDC37_N STK11-008 ENST00000593219
STK11 27 27 STK11-PRKAB1 Pkinase(52-309)-AMPKBI STK11-008 ENST00000593219
STK11 27 27 STK11-CAB39 Pkinase(52-309)-Mo25 STK11-008 ENST00000593219
STK11 27 27 STK11-CAB39L Pkinase(52-309)-Mo25 STK11-008 ENST00000593219

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT

*Transcripts of this gene has been found as dMDT in these disease types

Samples showing lost interactions due to MDT switch
Sample ID Disease Gene Name 1 Gene Name 2 Transcript Name dMDT
8f259997-f80c-4516-a7e6-f8c888f008d4 Skin.Skin-Melanoma STK11 STRADB STK11-008 ENST00000593219
8f259997-f80c-4516-a7e6-f8c888f008d4 Skin.Skin-Melanoma STK11 RPS6KB1 STK11-008 ENST00000593219
8f259997-f80c-4516-a7e6-f8c888f008d4 Skin.Skin-Melanoma STK11 MARK4 STK11-008 ENST00000593219
8f259997-f80c-4516-a7e6-f8c888f008d4 Skin.Skin-Melanoma STK11 SIK1 STK11-008 ENST00000593219
8f259997-f80c-4516-a7e6-f8c888f008d4 Skin.Skin-Melanoma STK11 SIK2 STK11-008 ENST00000593219
8f259997-f80c-4516-a7e6-f8c888f008d4 Skin.Skin-Melanoma STK11 PRKACA STK11-008 ENST00000593219
8f259997-f80c-4516-a7e6-f8c888f008d4 Skin.Skin-Melanoma STK11 BRSK1 STK11-008 ENST00000593219
8f259997-f80c-4516-a7e6-f8c888f008d4 Skin.Skin-Melanoma STK11 BRSK2 STK11-008 ENST00000593219
8f259997-f80c-4516-a7e6-f8c888f008d4 Skin.Skin-Melanoma STK11 STRADA STK11-008 ENST00000593219
8f259997-f80c-4516-a7e6-f8c888f008d4 Skin.Skin-Melanoma STK11 PRKAA1 STK11-008 ENST00000593219
8f259997-f80c-4516-a7e6-f8c888f008d4 Skin.Skin-Melanoma STK11 PRKAA2 STK11-008 ENST00000593219
8f259997-f80c-4516-a7e6-f8c888f008d4 Skin.Skin-Melanoma STK11 MST4 STK11-008 ENST00000593219
8f259997-f80c-4516-a7e6-f8c888f008d4 Skin.Skin-Melanoma STK11 MARK2 STK11-008 ENST00000593219
8f259997-f80c-4516-a7e6-f8c888f008d4 Skin.Skin-Melanoma STK11 KRAS STK11-008 ENST00000593219
8f259997-f80c-4516-a7e6-f8c888f008d4 Skin.Skin-Melanoma STK11 RAC3 STK11-008 ENST00000593219
8f259997-f80c-4516-a7e6-f8c888f008d4 Skin.Skin-Melanoma STK11 HRAS STK11-008 ENST00000593219
8f259997-f80c-4516-a7e6-f8c888f008d4 Skin.Skin-Melanoma STK11 RAC1 STK11-008 ENST00000593219
8f259997-f80c-4516-a7e6-f8c888f008d4 Skin.Skin-Melanoma STK11 NRAS STK11-008 ENST00000593219
8f259997-f80c-4516-a7e6-f8c888f008d4 Skin.Skin-Melanoma STK11 IRS1 STK11-008 ENST00000593219
8f259997-f80c-4516-a7e6-f8c888f008d4 Skin.Skin-Melanoma STK11 HSP90AA1 STK11-008 ENST00000593219
8f259997-f80c-4516-a7e6-f8c888f008d4 Skin.Skin-Melanoma STK11 PPM1A STK11-008 ENST00000593219
8f259997-f80c-4516-a7e6-f8c888f008d4 Skin.Skin-Melanoma STK11 PTEN STK11-008 ENST00000593219
8f259997-f80c-4516-a7e6-f8c888f008d4 Skin.Skin-Melanoma STK11 CDKN1A STK11-008 ENST00000593219
8f259997-f80c-4516-a7e6-f8c888f008d4 Skin.Skin-Melanoma STK11 CDC37 STK11-008 ENST00000593219
8f259997-f80c-4516-a7e6-f8c888f008d4 Skin.Skin-Melanoma STK11 PRKAB1 STK11-008 ENST00000593219
8f259997-f80c-4516-a7e6-f8c888f008d4 Skin.Skin-Melanoma STK11 CAB39 STK11-008 ENST00000593219
8f259997-f80c-4516-a7e6-f8c888f008d4 Skin.Skin-Melanoma STK11 CAB39L STK11-008 ENST00000593219
c970e2a6-4393-4641-9eea-33a022e23c53 Skin.Skin-Melanoma STK11 STRADB STK11-008 ENST00000593219
c970e2a6-4393-4641-9eea-33a022e23c53 Skin.Skin-Melanoma STK11 RPS6KB1 STK11-008 ENST00000593219
c970e2a6-4393-4641-9eea-33a022e23c53 Skin.Skin-Melanoma STK11 MARK4 STK11-008 ENST00000593219
c970e2a6-4393-4641-9eea-33a022e23c53 Skin.Skin-Melanoma STK11 SIK1 STK11-008 ENST00000593219
c970e2a6-4393-4641-9eea-33a022e23c53 Skin.Skin-Melanoma STK11 SIK2 STK11-008 ENST00000593219
c970e2a6-4393-4641-9eea-33a022e23c53 Skin.Skin-Melanoma STK11 PRKACA STK11-008 ENST00000593219
c970e2a6-4393-4641-9eea-33a022e23c53 Skin.Skin-Melanoma STK11 BRSK1 STK11-008 ENST00000593219
c970e2a6-4393-4641-9eea-33a022e23c53 Skin.Skin-Melanoma STK11 BRSK2 STK11-008 ENST00000593219
c970e2a6-4393-4641-9eea-33a022e23c53 Skin.Skin-Melanoma STK11 STRADA STK11-008 ENST00000593219
c970e2a6-4393-4641-9eea-33a022e23c53 Skin.Skin-Melanoma STK11 PRKAA1 STK11-008 ENST00000593219
c970e2a6-4393-4641-9eea-33a022e23c53 Skin.Skin-Melanoma STK11 PRKAA2 STK11-008 ENST00000593219
c970e2a6-4393-4641-9eea-33a022e23c53 Skin.Skin-Melanoma STK11 MST4 STK11-008 ENST00000593219
c970e2a6-4393-4641-9eea-33a022e23c53 Skin.Skin-Melanoma STK11 MARK2 STK11-008 ENST00000593219
c970e2a6-4393-4641-9eea-33a022e23c53 Skin.Skin-Melanoma STK11 KRAS STK11-008 ENST00000593219
c970e2a6-4393-4641-9eea-33a022e23c53 Skin.Skin-Melanoma STK11 RAC3 STK11-008 ENST00000593219
c970e2a6-4393-4641-9eea-33a022e23c53 Skin.Skin-Melanoma STK11 HRAS STK11-008 ENST00000593219
c970e2a6-4393-4641-9eea-33a022e23c53 Skin.Skin-Melanoma STK11 RAC1 STK11-008 ENST00000593219
c970e2a6-4393-4641-9eea-33a022e23c53 Skin.Skin-Melanoma STK11 NRAS STK11-008 ENST00000593219
c970e2a6-4393-4641-9eea-33a022e23c53 Skin.Skin-Melanoma STK11 IRS1 STK11-008 ENST00000593219
c970e2a6-4393-4641-9eea-33a022e23c53 Skin.Skin-Melanoma STK11 HSP90AA1 STK11-008 ENST00000593219
c970e2a6-4393-4641-9eea-33a022e23c53 Skin.Skin-Melanoma STK11 PPM1A STK11-008 ENST00000593219
c970e2a6-4393-4641-9eea-33a022e23c53 Skin.Skin-Melanoma STK11 PTEN STK11-008 ENST00000593219
c970e2a6-4393-4641-9eea-33a022e23c53 Skin.Skin-Melanoma STK11 CDKN1A STK11-008 ENST00000593219
c970e2a6-4393-4641-9eea-33a022e23c53 Skin.Skin-Melanoma STK11 CDC37 STK11-008 ENST00000593219
c970e2a6-4393-4641-9eea-33a022e23c53 Skin.Skin-Melanoma STK11 PRKAB1 STK11-008 ENST00000593219
c970e2a6-4393-4641-9eea-33a022e23c53 Skin.Skin-Melanoma STK11 CAB39 STK11-008 ENST00000593219
c970e2a6-4393-4641-9eea-33a022e23c53 Skin.Skin-Melanoma STK11 CAB39L STK11-008 ENST00000593219