CanIsoNet

Gene Name:

Protein Interaction Network

Interaction losses of dMDT
*only proteins having domain-domain interaction information are taken into consideration
Gene
Name
# of
Interaction*
# of Missed
Interaction
Interaction
Lost
Domain Int
Lost
Transcript Name dMDT
WNK4 6 0 None None WNK4-002 ENST00000591448
WNK4 6 6 WNK4-STK39 Pkinase(179-432)-Pkinase WNK4-002 ENST00000591448
WNK4 6 6 WNK4-RPS27A Pkinase(179-432)-ubiquitin WNK4-002 ENST00000591448
WNK4 6 6 WNK4-UBB Pkinase(179-432)-ubiquitin WNK4-002 ENST00000591448
WNK4 6 6 WNK4-UBC Pkinase(179-432)-ubiquitin WNK4-002 ENST00000591448
WNK4 6 6 WNK4-UBA52 Pkinase(179-432)-ubiquitin WNK4-002 ENST00000591448
WNK4 6 6 WNK4-ITSN1 Pkinase_Tyr(174-430)-SH3_9 WNK4-002 ENST00000591448

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT

*Transcripts of this gene has been found as dMDT in these disease types

Samples showing lost interactions due to MDT switch
Sample ID Disease Gene Name 1 Gene Name 2 Transcript Name dMDT
ef37a73c-e0a0-4ff6-83a3-6befcdcb51c6 Breast.Breast-AdenoCA WNK4 - WNK4-002 ENST00000591448
87ddacee-93c2-4a9a-9e53-3af7fe5c0886 Kidney.Kidney-RCC WNK4 STK39 WNK4-002 ENST00000591448
87ddacee-93c2-4a9a-9e53-3af7fe5c0886 Kidney.Kidney-RCC WNK4 RPS27A WNK4-002 ENST00000591448
87ddacee-93c2-4a9a-9e53-3af7fe5c0886 Kidney.Kidney-RCC WNK4 UBB WNK4-002 ENST00000591448
87ddacee-93c2-4a9a-9e53-3af7fe5c0886 Kidney.Kidney-RCC WNK4 UBC WNK4-002 ENST00000591448
87ddacee-93c2-4a9a-9e53-3af7fe5c0886 Kidney.Kidney-RCC WNK4 UBA52 WNK4-002 ENST00000591448
87ddacee-93c2-4a9a-9e53-3af7fe5c0886 Kidney.Kidney-RCC WNK4 ITSN1 WNK4-002 ENST00000591448
b8862635-21cd-405b-b757-8ee924a7a826 Kidney.Kidney-RCC WNK4 STK39 WNK4-002 ENST00000591448
b8862635-21cd-405b-b757-8ee924a7a826 Kidney.Kidney-RCC WNK4 RPS27A WNK4-002 ENST00000591448
b8862635-21cd-405b-b757-8ee924a7a826 Kidney.Kidney-RCC WNK4 UBB WNK4-002 ENST00000591448
b8862635-21cd-405b-b757-8ee924a7a826 Kidney.Kidney-RCC WNK4 UBC WNK4-002 ENST00000591448
b8862635-21cd-405b-b757-8ee924a7a826 Kidney.Kidney-RCC WNK4 UBA52 WNK4-002 ENST00000591448
b8862635-21cd-405b-b757-8ee924a7a826 Kidney.Kidney-RCC WNK4 ITSN1 WNK4-002 ENST00000591448
65537c4d-ad30-4211-b819-094621c316f4 Ovary.Ovary-AdenoCA WNK4 STK39 WNK4-002 ENST00000591448
65537c4d-ad30-4211-b819-094621c316f4 Ovary.Ovary-AdenoCA WNK4 RPS27A WNK4-002 ENST00000591448
65537c4d-ad30-4211-b819-094621c316f4 Ovary.Ovary-AdenoCA WNK4 UBB WNK4-002 ENST00000591448
65537c4d-ad30-4211-b819-094621c316f4 Ovary.Ovary-AdenoCA WNK4 UBC WNK4-002 ENST00000591448
65537c4d-ad30-4211-b819-094621c316f4 Ovary.Ovary-AdenoCA WNK4 UBA52 WNK4-002 ENST00000591448
65537c4d-ad30-4211-b819-094621c316f4 Ovary.Ovary-AdenoCA WNK4 ITSN1 WNK4-002 ENST00000591448
70a93713-e154-46c8-9360-b873c63f0f05 Prostate.Prost-AdenoCA WNK4 STK39 WNK4-002 ENST00000591448
70a93713-e154-46c8-9360-b873c63f0f05 Prostate.Prost-AdenoCA WNK4 RPS27A WNK4-002 ENST00000591448
70a93713-e154-46c8-9360-b873c63f0f05 Prostate.Prost-AdenoCA WNK4 UBB WNK4-002 ENST00000591448
70a93713-e154-46c8-9360-b873c63f0f05 Prostate.Prost-AdenoCA WNK4 UBC WNK4-002 ENST00000591448
70a93713-e154-46c8-9360-b873c63f0f05 Prostate.Prost-AdenoCA WNK4 UBA52 WNK4-002 ENST00000591448
70a93713-e154-46c8-9360-b873c63f0f05 Prostate.Prost-AdenoCA WNK4 ITSN1 WNK4-002 ENST00000591448