CanIsoNet

Gene Name:

Transcript ID:
Transcript Name:
dMDT Interaction Network

Protein interaction losses due to MDT switch
*only proteins having domain-domain interaction information are taken into consideration
Number of Total Interaction:
Number of Lost Interaction:
Gene Name Interaction Lost Lost Domain (Region) Lost Domain - Domain Interaction
NCOA2 NCOA2-CLOCK PAS(119-175) PAS(119-175) - HLH
NCOA2 NCOA2-NPAS2 PAS(119-175) PAS(119-175) - HLH
NCOA2 NCOA2-SREBF2 PAS(119-175) PAS(119-175) - HLH
NCOA2 NCOA2-ARNTL PAS(119-175) PAS(119-175) - HLH
NCOA2 NCOA2-NCOA1 PAS(119-175) PAS(119-175) - PAS
NCOA2 NCOA2-HIF1A PAS(119-175) PAS(119-175) - PAS
NCOA2 NCOA2-NCOA3 PAS(119-175) PAS(119-175) - PAS
NCOA2 NCOA2-ESR1 SRC-1(636-709) SRC-1(636-709) - Hormone_recep
NCOA2 NCOA2-NR3C1 SRC-1(636-709) SRC-1(636-709) - Hormone_recep
NCOA2 NCOA2-RARA SRC-1(636-709) SRC-1(636-709) - Hormone_recep
NCOA2 NCOA2-RORA SRC-1(636-709) SRC-1(636-709) - Hormone_recep
NCOA2 NCOA2-PPARA SRC-1(636-709) SRC-1(636-709) - Hormone_recep
NCOA2 NCOA2-THRA SRC-1(636-709) SRC-1(636-709) - Hormone_recep
NCOA2 NCOA2-PPARG SRC-1(636-709) SRC-1(636-709) - Hormone_recep
NCOA2 NCOA2-ESR2 SRC-1(636-709) SRC-1(636-709) - Hormone_recep
NCOA2 NCOA2-THRB SRC-1(636-709) SRC-1(636-709) - Hormone_recep
NCOA2 NCOA2-AR SRC-1(636-709) SRC-1(636-709) - Hormone_recep
NCOA2 NCOA2-VDR SRC-1(636-709) SRC-1(636-709) - Hormone_recep

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
Sample ID Disease Type Gene Name 1 Gene Name 2 Transcript Name dMDT
151bb98d-d961-49c1-a54f-8293b3ab2ebd Colon.ColoRect-AdenoCA NCOA2 CLOCK NCOA2-201 ENST00000267974
151bb98d-d961-49c1-a54f-8293b3ab2ebd Colon.ColoRect-AdenoCA NCOA2 NPAS2 NCOA2-201 ENST00000267974
151bb98d-d961-49c1-a54f-8293b3ab2ebd Colon.ColoRect-AdenoCA NCOA2 SREBF2 NCOA2-201 ENST00000267974
151bb98d-d961-49c1-a54f-8293b3ab2ebd Colon.ColoRect-AdenoCA NCOA2 ARNTL NCOA2-201 ENST00000267974
151bb98d-d961-49c1-a54f-8293b3ab2ebd Colon.ColoRect-AdenoCA NCOA2 NCOA1 NCOA2-201 ENST00000267974
151bb98d-d961-49c1-a54f-8293b3ab2ebd Colon.ColoRect-AdenoCA NCOA2 HIF1A NCOA2-201 ENST00000267974
151bb98d-d961-49c1-a54f-8293b3ab2ebd Colon.ColoRect-AdenoCA NCOA2 NCOA3 NCOA2-201 ENST00000267974
151bb98d-d961-49c1-a54f-8293b3ab2ebd Colon.ColoRect-AdenoCA NCOA2 ESR1 NCOA2-201 ENST00000267974
151bb98d-d961-49c1-a54f-8293b3ab2ebd Colon.ColoRect-AdenoCA NCOA2 NR3C1 NCOA2-201 ENST00000267974
151bb98d-d961-49c1-a54f-8293b3ab2ebd Colon.ColoRect-AdenoCA NCOA2 RARA NCOA2-201 ENST00000267974
151bb98d-d961-49c1-a54f-8293b3ab2ebd Colon.ColoRect-AdenoCA NCOA2 RORA NCOA2-201 ENST00000267974
151bb98d-d961-49c1-a54f-8293b3ab2ebd Colon.ColoRect-AdenoCA NCOA2 PPARA NCOA2-201 ENST00000267974
151bb98d-d961-49c1-a54f-8293b3ab2ebd Colon.ColoRect-AdenoCA NCOA2 THRA NCOA2-201 ENST00000267974
151bb98d-d961-49c1-a54f-8293b3ab2ebd Colon.ColoRect-AdenoCA NCOA2 PPARG NCOA2-201 ENST00000267974
151bb98d-d961-49c1-a54f-8293b3ab2ebd Colon.ColoRect-AdenoCA NCOA2 ESR2 NCOA2-201 ENST00000267974
151bb98d-d961-49c1-a54f-8293b3ab2ebd Colon.ColoRect-AdenoCA NCOA2 THRB NCOA2-201 ENST00000267974
151bb98d-d961-49c1-a54f-8293b3ab2ebd Colon.ColoRect-AdenoCA NCOA2 AR NCOA2-201 ENST00000267974
151bb98d-d961-49c1-a54f-8293b3ab2ebd Colon.ColoRect-AdenoCA NCOA2 VDR NCOA2-201 ENST00000267974
310820cc-fc05-45c6-8f04-a44db0828686 Colon.ColoRect-AdenoCA NCOA2 CLOCK NCOA2-201 ENST00000267974
310820cc-fc05-45c6-8f04-a44db0828686 Colon.ColoRect-AdenoCA NCOA2 NPAS2 NCOA2-201 ENST00000267974
310820cc-fc05-45c6-8f04-a44db0828686 Colon.ColoRect-AdenoCA NCOA2 SREBF2 NCOA2-201 ENST00000267974
310820cc-fc05-45c6-8f04-a44db0828686 Colon.ColoRect-AdenoCA NCOA2 ARNTL NCOA2-201 ENST00000267974
310820cc-fc05-45c6-8f04-a44db0828686 Colon.ColoRect-AdenoCA NCOA2 NCOA1 NCOA2-201 ENST00000267974
310820cc-fc05-45c6-8f04-a44db0828686 Colon.ColoRect-AdenoCA NCOA2 HIF1A NCOA2-201 ENST00000267974
310820cc-fc05-45c6-8f04-a44db0828686 Colon.ColoRect-AdenoCA NCOA2 NCOA3 NCOA2-201 ENST00000267974
310820cc-fc05-45c6-8f04-a44db0828686 Colon.ColoRect-AdenoCA NCOA2 ESR1 NCOA2-201 ENST00000267974
310820cc-fc05-45c6-8f04-a44db0828686 Colon.ColoRect-AdenoCA NCOA2 NR3C1 NCOA2-201 ENST00000267974
310820cc-fc05-45c6-8f04-a44db0828686 Colon.ColoRect-AdenoCA NCOA2 RARA NCOA2-201 ENST00000267974
310820cc-fc05-45c6-8f04-a44db0828686 Colon.ColoRect-AdenoCA NCOA2 RORA NCOA2-201 ENST00000267974
310820cc-fc05-45c6-8f04-a44db0828686 Colon.ColoRect-AdenoCA NCOA2 PPARA NCOA2-201 ENST00000267974
310820cc-fc05-45c6-8f04-a44db0828686 Colon.ColoRect-AdenoCA NCOA2 THRA NCOA2-201 ENST00000267974
310820cc-fc05-45c6-8f04-a44db0828686 Colon.ColoRect-AdenoCA NCOA2 PPARG NCOA2-201 ENST00000267974
310820cc-fc05-45c6-8f04-a44db0828686 Colon.ColoRect-AdenoCA NCOA2 ESR2 NCOA2-201 ENST00000267974
310820cc-fc05-45c6-8f04-a44db0828686 Colon.ColoRect-AdenoCA NCOA2 THRB NCOA2-201 ENST00000267974
310820cc-fc05-45c6-8f04-a44db0828686 Colon.ColoRect-AdenoCA NCOA2 AR NCOA2-201 ENST00000267974
310820cc-fc05-45c6-8f04-a44db0828686 Colon.ColoRect-AdenoCA NCOA2 VDR NCOA2-201 ENST00000267974
82bb01e9-a659-417b-b9e8-831a76277a21 Colon.ColoRect-AdenoCA NCOA2 CLOCK NCOA2-201 ENST00000267974
82bb01e9-a659-417b-b9e8-831a76277a21 Colon.ColoRect-AdenoCA NCOA2 NPAS2 NCOA2-201 ENST00000267974
82bb01e9-a659-417b-b9e8-831a76277a21 Colon.ColoRect-AdenoCA NCOA2 SREBF2 NCOA2-201 ENST00000267974
82bb01e9-a659-417b-b9e8-831a76277a21 Colon.ColoRect-AdenoCA NCOA2 ARNTL NCOA2-201 ENST00000267974
82bb01e9-a659-417b-b9e8-831a76277a21 Colon.ColoRect-AdenoCA NCOA2 NCOA1 NCOA2-201 ENST00000267974
82bb01e9-a659-417b-b9e8-831a76277a21 Colon.ColoRect-AdenoCA NCOA2 HIF1A NCOA2-201 ENST00000267974
82bb01e9-a659-417b-b9e8-831a76277a21 Colon.ColoRect-AdenoCA NCOA2 NCOA3 NCOA2-201 ENST00000267974
82bb01e9-a659-417b-b9e8-831a76277a21 Colon.ColoRect-AdenoCA NCOA2 ESR1 NCOA2-201 ENST00000267974
82bb01e9-a659-417b-b9e8-831a76277a21 Colon.ColoRect-AdenoCA NCOA2 NR3C1 NCOA2-201 ENST00000267974
82bb01e9-a659-417b-b9e8-831a76277a21 Colon.ColoRect-AdenoCA NCOA2 RARA NCOA2-201 ENST00000267974
82bb01e9-a659-417b-b9e8-831a76277a21 Colon.ColoRect-AdenoCA NCOA2 RORA NCOA2-201 ENST00000267974
82bb01e9-a659-417b-b9e8-831a76277a21 Colon.ColoRect-AdenoCA NCOA2 PPARA NCOA2-201 ENST00000267974
82bb01e9-a659-417b-b9e8-831a76277a21 Colon.ColoRect-AdenoCA NCOA2 THRA NCOA2-201 ENST00000267974
82bb01e9-a659-417b-b9e8-831a76277a21 Colon.ColoRect-AdenoCA NCOA2 PPARG NCOA2-201 ENST00000267974
82bb01e9-a659-417b-b9e8-831a76277a21 Colon.ColoRect-AdenoCA NCOA2 ESR2 NCOA2-201 ENST00000267974
82bb01e9-a659-417b-b9e8-831a76277a21 Colon.ColoRect-AdenoCA NCOA2 THRB NCOA2-201 ENST00000267974
82bb01e9-a659-417b-b9e8-831a76277a21 Colon.ColoRect-AdenoCA NCOA2 AR NCOA2-201 ENST00000267974
82bb01e9-a659-417b-b9e8-831a76277a21 Colon.ColoRect-AdenoCA NCOA2 VDR NCOA2-201 ENST00000267974
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA NCOA2 CLOCK NCOA2-201 ENST00000267974
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA NCOA2 NPAS2 NCOA2-201 ENST00000267974
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA NCOA2 SREBF2 NCOA2-201 ENST00000267974
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA NCOA2 ARNTL NCOA2-201 ENST00000267974
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA NCOA2 NCOA1 NCOA2-201 ENST00000267974
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA NCOA2 HIF1A NCOA2-201 ENST00000267974
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA NCOA2 NCOA3 NCOA2-201 ENST00000267974
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA NCOA2 ESR1 NCOA2-201 ENST00000267974
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA NCOA2 NR3C1 NCOA2-201 ENST00000267974
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA NCOA2 RARA NCOA2-201 ENST00000267974
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA NCOA2 RORA NCOA2-201 ENST00000267974
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA NCOA2 PPARA NCOA2-201 ENST00000267974
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA NCOA2 THRA NCOA2-201 ENST00000267974
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA NCOA2 PPARG NCOA2-201 ENST00000267974
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA NCOA2 ESR2 NCOA2-201 ENST00000267974
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA NCOA2 THRB NCOA2-201 ENST00000267974
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA NCOA2 AR NCOA2-201 ENST00000267974
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA NCOA2 VDR NCOA2-201 ENST00000267974
Interaction losses with Clinvar proteins
Gene Name
AR
ESR1
ESR2
NR3C1
PPARG
RARA
RORA
THRA
THRB
VDR