dMDT Interaction Network
Protein interaction losses due to MDT switch
| Gene Name | Interaction Lost | Lost Domain (Region) | Lost Domain - Domain Interaction |
|---|---|---|---|
| NEDD8 | NEDD8-TGFBR2 | ubiquitin(6-74) | ubiquitin(6-74) - Pkinase |
| NEDD8 | NEDD8-CDC34 | ubiquitin(6-74) | ubiquitin(6-74) - UQ_con |
| NEDD8 | NEDD8-UBE2M | ubiquitin(6-74) | ubiquitin(6-74) - UQ_con |
| NEDD8 | NEDD8-UBE2F | ubiquitin(6-74) | ubiquitin(6-74) - UQ_con |
| NEDD8 | NEDD8-UBE2F-SCLY | ubiquitin(6-74) | ubiquitin(6-74) - UQ_con |
| NEDD8 | NEDD8-UBC | ubiquitin(6-74) | ubiquitin(6-74) - ubiquitin |
| NEDD8 | NEDD8-UBL5 | ubiquitin(6-74) | ubiquitin(6-74) - ubiquitin |
| NEDD8 | NEDD8-PARK2 | ubiquitin(6-74) | ubiquitin(6-74) - ubiquitin |
| NEDD8 | NEDD8-USP21 | ubiquitin(6-74) | ubiquitin(6-74) - UCH |
| NEDD8 | NEDD8-CBL | ubiquitin(6-74) | ubiquitin(6-74) - UBA |
| NEDD8 | NEDD8-MDM2 | ubiquitin(6-74) | ubiquitin(6-74) - zf-RanBP |
| NEDD8 | NEDD8-UBA2 | ubiquitin(6-74) | ubiquitin(6-74) - ThiF |
| NEDD8 | NEDD8-NAE1 | ubiquitin(6-74) | ubiquitin(6-74) - ThiF |
| NEDD8 | NEDD8-UBA1 | ubiquitin(6-74) | ubiquitin(6-74) - ThiF |
| NEDD8 | NEDD8-UBA3 | ubiquitin(6-74) | ubiquitin(6-74) - ThiF |
| NEDD8 | NEDD8-UCHL3 | ubiquitin(6-74) | ubiquitin(6-74) - Peptidase_C12 |
| NEDD8 | NEDD8-COPS6 | ubiquitin(6-74) | ubiquitin(6-74) - JAB |
| NEDD8 | NEDD8-COPS5 | ubiquitin(6-74) | ubiquitin(6-74) - JAB |
| NEDD8 | NEDD8-PSMD4 | ubiquitin(6-74) | ubiquitin(6-74) - UIM |
| NEDD8 | NEDD8-SENP8 | ubiquitin(6-74) | ubiquitin(6-74) - Peptidase_C48 |
| NEDD8 | NEDD8-SKP1 | ubiquitin(6-74) | ubiquitin(6-74) - Skp1_POZ |
| NEDD8 | NEDD8-TCEB1 | ubiquitin(6-74) | ubiquitin(6-74) - Skp1_POZ |
| NEDD8 | NEDD8-CUL3 | ubiquitin(6-74) | ubiquitin(6-74) - Cullin_Nedd8 |
| NEDD8 | NEDD8-CUL1 | ubiquitin(6-74) | ubiquitin(6-74) - Cullin_Nedd8 |
| NEDD8 | NEDD8-CUL4A | ubiquitin(6-74) | ubiquitin(6-74) - Cullin_Nedd8 |
| NEDD8 | NEDD8-CUL5 | ubiquitin(6-74) | ubiquitin(6-74) - Cullin_Nedd8 |
| NEDD8 | NEDD8-CUL4B | ubiquitin(6-74) | ubiquitin(6-74) - Cullin_Nedd8 |
| NEDD8 | NEDD8-CUL2 | ubiquitin(6-74) | ubiquitin(6-74) - Cullin_Nedd8 |
| NEDD8 | NEDD8-RBX1 | ubiquitin(6-74) | ubiquitin(6-74) - zf-rbx1 |
| NEDD8 | NEDD8-SKP2 | ubiquitin(6-74) | ubiquitin(6-74) - F-box-like |
| NEDD8 | NEDD8-BTRC | ubiquitin(6-74) | ubiquitin(6-74) - F-box-like |
| NEDD8 | NEDD8-FBXO11 | ubiquitin(6-74) | ubiquitin(6-74) - F-box-like |
Network Density Score: %
The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch