dMDT Interaction Network
Protein interaction losses due to MDT switch
| Gene Name | Interaction Lost | Lost Domain (Region) | Lost Domain - Domain Interaction |
|---|---|---|---|
| NFYC | NFYC-NFYB | Histone(36-107) | Histone(36-107) - Histone |
| NFYC | NFYC-TBP | CBFD_NFYB_HMF(42-105) | CBFD_NFYB_HMF(42-105) - TBP |
| NFYC | NFYC-TBPL2 | CBFD_NFYB_HMF(42-105) | CBFD_NFYB_HMF(42-105) - TBP |
| NFYC | NFYC-POLE3 | CBFD_NFYB_HMF(42-105) | CBFD_NFYB_HMF(42-105) - CBFD_NFYB_HMF |
| NFYC | NFYC-NFYA | CBFD_NFYB_HMF(42-105) | CBFD_NFYB_HMF(42-105) - CBFB_NFYA |
Network Density Score: %
The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
| Sample ID | Disease Type | Gene Name 1 | Gene Name 2 | Transcript Name | dMDT |
|---|---|---|---|---|---|
| 37725090-996e-4ab2-bbf6-dc3d2970e387 | Esophagus.Eso-AdenoCA | NFYC | NFYB | NFYC-016 | ENST00000414185 |
| 37725090-996e-4ab2-bbf6-dc3d2970e387 | Esophagus.Eso-AdenoCA | NFYC | TBP | NFYC-016 | ENST00000414185 |
| 37725090-996e-4ab2-bbf6-dc3d2970e387 | Esophagus.Eso-AdenoCA | NFYC | TBPL2 | NFYC-016 | ENST00000414185 |
| 37725090-996e-4ab2-bbf6-dc3d2970e387 | Esophagus.Eso-AdenoCA | NFYC | POLE3 | NFYC-016 | ENST00000414185 |
| 37725090-996e-4ab2-bbf6-dc3d2970e387 | Esophagus.Eso-AdenoCA | NFYC | NFYA | NFYC-016 | ENST00000414185 |
Interaction losses with Clinvar proteins
| Gene Name |
|---|
| TBP |