CanIsoNet

Gene Name:

Transcript ID:
Transcript Name:
dMDT Interaction Network

Protein interaction losses due to MDT switch
*only proteins having domain-domain interaction information are taken into consideration
Number of Total Interaction:
Number of Lost Interaction:
Gene Name Interaction Lost Lost Domain (Region) Lost Domain - Domain Interaction
RASGRP3 RASGRP3-RASGRP1 C1_1(495-544) C1_1(495-544) - C1_1
RASGRP3 RASGRP3-RRAS RasGEF(151-331) RasGEF(151-331) - Ras
RASGRP3 RASGRP3-KRAS RasGEF(151-331) RasGEF(151-331) - Ras
RASGRP3 RASGRP3-HRAS RasGEF(151-331) RasGEF(151-331) - Ras
RASGRP3 RASGRP3-RAP1A RasGEF(151-331) RasGEF(151-331) - Ras
RASGRP3 RASGRP3-NRAS RasGEF(151-331) RasGEF(151-331) - Ras

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
Sample ID Disease Type Gene Name 1 Gene Name 2 Transcript Name dMDT
34dda809-a7af-411f-ab80-b021b077eaf9 Thyroid.Thy-AdenoCA RASGRP3 RASGRP1 RASGRP3-012 ENST00000442390
34dda809-a7af-411f-ab80-b021b077eaf9 Thyroid.Thy-AdenoCA RASGRP3 RRAS RASGRP3-012 ENST00000442390
34dda809-a7af-411f-ab80-b021b077eaf9 Thyroid.Thy-AdenoCA RASGRP3 KRAS RASGRP3-012 ENST00000442390
34dda809-a7af-411f-ab80-b021b077eaf9 Thyroid.Thy-AdenoCA RASGRP3 HRAS RASGRP3-012 ENST00000442390
34dda809-a7af-411f-ab80-b021b077eaf9 Thyroid.Thy-AdenoCA RASGRP3 RAP1A RASGRP3-012 ENST00000442390
34dda809-a7af-411f-ab80-b021b077eaf9 Thyroid.Thy-AdenoCA RASGRP3 NRAS RASGRP3-012 ENST00000442390
4ab212b1-2a55-4850-8610-8a3c96ed0c1b Thyroid.Thy-AdenoCA RASGRP3 RASGRP1 RASGRP3-012 ENST00000442390
4ab212b1-2a55-4850-8610-8a3c96ed0c1b Thyroid.Thy-AdenoCA RASGRP3 RRAS RASGRP3-012 ENST00000442390
4ab212b1-2a55-4850-8610-8a3c96ed0c1b Thyroid.Thy-AdenoCA RASGRP3 KRAS RASGRP3-012 ENST00000442390
4ab212b1-2a55-4850-8610-8a3c96ed0c1b Thyroid.Thy-AdenoCA RASGRP3 HRAS RASGRP3-012 ENST00000442390
4ab212b1-2a55-4850-8610-8a3c96ed0c1b Thyroid.Thy-AdenoCA RASGRP3 RAP1A RASGRP3-012 ENST00000442390
4ab212b1-2a55-4850-8610-8a3c96ed0c1b Thyroid.Thy-AdenoCA RASGRP3 NRAS RASGRP3-012 ENST00000442390
C262A55B-8CF2-4C47-A867-F010361E22AC Thyroid.Thy-AdenoCA RASGRP3 RASGRP1 RASGRP3-012 ENST00000442390
C262A55B-8CF2-4C47-A867-F010361E22AC Thyroid.Thy-AdenoCA RASGRP3 RRAS RASGRP3-012 ENST00000442390
C262A55B-8CF2-4C47-A867-F010361E22AC Thyroid.Thy-AdenoCA RASGRP3 KRAS RASGRP3-012 ENST00000442390
C262A55B-8CF2-4C47-A867-F010361E22AC Thyroid.Thy-AdenoCA RASGRP3 HRAS RASGRP3-012 ENST00000442390
C262A55B-8CF2-4C47-A867-F010361E22AC Thyroid.Thy-AdenoCA RASGRP3 RAP1A RASGRP3-012 ENST00000442390
C262A55B-8CF2-4C47-A867-F010361E22AC Thyroid.Thy-AdenoCA RASGRP3 NRAS RASGRP3-012 ENST00000442390
Interaction losses with Clinvar proteins
Gene Name
HRAS
KRAS
NRAS
RASGRP1