dMDT Interaction Network
Protein interaction losses due to MDT switch
| Gene Name | Interaction Lost | Lost Domain (Region) | Lost Domain - Domain Interaction |
|---|---|---|---|
| DYRK1A | DYRK1A-PHYHIPL | Pkinase(159-479) | Pkinase(159-479) - fn3 |
| DYRK1A | DYRK1A-CCNL2 | Pkinase(159-479) | Pkinase(159-479) - Cyclin_N |
| DYRK1A | DYRK1A-DNM1 | Pkinase(159-479) | Pkinase(159-479) - PH |
| DYRK1A | DYRK1A-NOTCH1 | Pkinase(159-479) | Pkinase(159-479) - Ank_2 |
Network Density Score: %
The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
| Sample ID | Disease Type | Gene Name 1 | Gene Name 2 | Transcript Name | dMDT |
|---|---|---|---|---|---|
| c9e3d4c7-862b-4ef2-9a08-216fc44e0bdc | CervixUteri.Cervix-SCC | DYRK1A | PHYHIPL | DYRK1A-004 | ENST00000455097 |
| c9e3d4c7-862b-4ef2-9a08-216fc44e0bdc | CervixUteri.Cervix-SCC | DYRK1A | CCNL2 | DYRK1A-004 | ENST00000455097 |
| c9e3d4c7-862b-4ef2-9a08-216fc44e0bdc | CervixUteri.Cervix-SCC | DYRK1A | DNM1 | DYRK1A-004 | ENST00000455097 |
| c9e3d4c7-862b-4ef2-9a08-216fc44e0bdc | CervixUteri.Cervix-SCC | DYRK1A | NOTCH1 | DYRK1A-004 | ENST00000455097 |