dMDT Interaction Network
Protein interaction losses due to MDT switch
| Gene Name | Interaction Lost | Lost Domain (Region) | Lost Domain - Domain Interaction |
|---|---|---|---|
| LATS1 | LATS1-STK4 | Pkinase(906-1010) | Pkinase(906-1010) - Pkinase |
| LATS1 | LATS1-LATS2 | Pkinase(906-1010) | Pkinase(906-1010) - Pkinase |
| LATS1 | LATS1-STK3 | Pkinase(906-1010) | Pkinase(906-1010) - Pkinase |
| LATS1 | LATS1-PPP1R12A | Pkinase(906-1010) | Pkinase(906-1010) - Ank_2 |
Network Density Score: %
The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
| Sample ID | Disease Type | Gene Name 1 | Gene Name 2 | Transcript Name | dMDT |
|---|---|---|---|---|---|
| 37725090-996e-4ab2-bbf6-dc3d2970e387 | Esophagus.Eso-AdenoCA | LATS1 | STK4 | LATS1-007 | ENST00000458696 |
| 37725090-996e-4ab2-bbf6-dc3d2970e387 | Esophagus.Eso-AdenoCA | LATS1 | LATS2 | LATS1-007 | ENST00000458696 |
| 37725090-996e-4ab2-bbf6-dc3d2970e387 | Esophagus.Eso-AdenoCA | LATS1 | STK3 | LATS1-007 | ENST00000458696 |
| 37725090-996e-4ab2-bbf6-dc3d2970e387 | Esophagus.Eso-AdenoCA | LATS1 | PPP1R12A | LATS1-007 | ENST00000458696 |