dMDT Interaction Network
Protein interaction losses due to MDT switch
| Gene Name | Interaction Lost | Lost Domain (Region) | Lost Domain - Domain Interaction |
|---|---|---|---|
| SMC4 | SMC4-SMC2 | SMC_N(83-1270) | SMC_N(83-1270) - SMC_N |
| SMC4 | SMC4-RAD21 | SMC_N(83-1270) | SMC_N(83-1270) - Rad21_Rec8 |
| SMC4 | SMC4-RAD50 | SMC_N(83-1270) | SMC_N(83-1270) - AAA_23 |
Network Density Score: %
The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
| Sample ID | Disease Type | Gene Name 1 | Gene Name 2 | Transcript Name | dMDT |
|---|---|---|---|---|---|
| 37725090-996e-4ab2-bbf6-dc3d2970e387 | Esophagus.Eso-AdenoCA | SMC4 | SMC2 | SMC4-005 | ENST00000489573 |
| 37725090-996e-4ab2-bbf6-dc3d2970e387 | Esophagus.Eso-AdenoCA | SMC4 | RAD21 | SMC4-005 | ENST00000489573 |
| 37725090-996e-4ab2-bbf6-dc3d2970e387 | Esophagus.Eso-AdenoCA | SMC4 | RAD50 | SMC4-005 | ENST00000489573 |