CanIsoNet

Gene Name:

Transcript ID:
Transcript Name:
dMDT Interaction Network

Protein interaction losses due to MDT switch
*only proteins having domain-domain interaction information are taken into consideration
Number of Total Interaction:
Number of Lost Interaction:
Gene Name Interaction Lost Lost Domain (Region) Lost Domain - Domain Interaction
GEM GEM-BUB1B Ras(77-241) Ras(77-241) - Pkinase
GEM GEM-PLK1 Ras(77-241) Ras(77-241) - Pkinase
GEM GEM-AURKC Ras(77-241) Ras(77-241) - Pkinase
GEM GEM-CDC42 Ras(77-241) Ras(77-241) - Ras
GEM GEM-RACGAP1 Ras(77-241) Ras(77-241) - RhoGAP

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
Sample ID Disease Type Gene Name 1 Gene Name 2 Transcript Name dMDT
82bb01e9-a659-417b-b9e8-831a76277a21 Colon.ColoRect-AdenoCA GEM BUB1B GEM-005 ENST00000523433
82bb01e9-a659-417b-b9e8-831a76277a21 Colon.ColoRect-AdenoCA GEM PLK1 GEM-005 ENST00000523433
82bb01e9-a659-417b-b9e8-831a76277a21 Colon.ColoRect-AdenoCA GEM AURKC GEM-005 ENST00000523433
82bb01e9-a659-417b-b9e8-831a76277a21 Colon.ColoRect-AdenoCA GEM CDC42 GEM-005 ENST00000523433
82bb01e9-a659-417b-b9e8-831a76277a21 Colon.ColoRect-AdenoCA GEM RACGAP1 GEM-005 ENST00000523433
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA GEM BUB1B GEM-005 ENST00000523433
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA GEM PLK1 GEM-005 ENST00000523433
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA GEM AURKC GEM-005 ENST00000523433
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA GEM CDC42 GEM-005 ENST00000523433
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA GEM RACGAP1 GEM-005 ENST00000523433
dd96340b-cc6f-4a3f-b441-c7af1d86684e Colon.ColoRect-AdenoCA GEM BUB1B GEM-005 ENST00000523433
dd96340b-cc6f-4a3f-b441-c7af1d86684e Colon.ColoRect-AdenoCA GEM PLK1 GEM-005 ENST00000523433
dd96340b-cc6f-4a3f-b441-c7af1d86684e Colon.ColoRect-AdenoCA GEM AURKC GEM-005 ENST00000523433
dd96340b-cc6f-4a3f-b441-c7af1d86684e Colon.ColoRect-AdenoCA GEM CDC42 GEM-005 ENST00000523433
dd96340b-cc6f-4a3f-b441-c7af1d86684e Colon.ColoRect-AdenoCA GEM RACGAP1 GEM-005 ENST00000523433
Interaction losses with Clinvar proteins
Gene Name
AURKC
BUB1B
CDC42
RACGAP1