CanIsoNet

Gene Name:

Transcript ID:
Transcript Name:
dMDT Interaction Network

Protein interaction losses due to MDT switch
*only proteins having domain-domain interaction information are taken into consideration
Number of Total Interaction:
Number of Lost Interaction:
Gene Name Interaction Lost Lost Domain (Region) Lost Domain - Domain Interaction
CX3CL1 CX3CL1-CCR2 IL8(36-89) IL8(36-89) - 7tm_1
CX3CL1 CX3CL1-CCR5 IL8(36-89) IL8(36-89) - 7tm_1
CX3CL1 CX3CL1-CXCR1 IL8(36-89) IL8(36-89) - 7tm_1
CX3CL1 CX3CL1-CCR1 IL8(36-89) IL8(36-89) - 7tm_1
CX3CL1 CX3CL1-CXCR2 IL8(36-89) IL8(36-89) - 7tm_1
CX3CL1 CX3CL1-CX3CR1 IL8(36-89) IL8(36-89) - 7tm_1
CX3CL1 CX3CL1-CXCR3 IL8(36-89) IL8(36-89) - 7tm_1
CX3CL1 CX3CL1-CCR3 IL8(36-89) IL8(36-89) - 7tm_1

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
Sample ID Disease Type Gene Name 1 Gene Name 2 Transcript Name dMDT
SRR19243471 Alzheimer's disease CX3CL1 CCR2 CX3CL1-004 ENST00000564948
SRR19243471 Alzheimer's disease CX3CL1 CCR5 CX3CL1-004 ENST00000564948
SRR19243471 Alzheimer's disease CX3CL1 CXCR1 CX3CL1-004 ENST00000564948
SRR19243471 Alzheimer's disease CX3CL1 CCR1 CX3CL1-004 ENST00000564948
SRR19243471 Alzheimer's disease CX3CL1 CXCR2 CX3CL1-004 ENST00000564948
SRR19243471 Alzheimer's disease CX3CL1 CX3CR1 CX3CL1-004 ENST00000564948
SRR19243471 Alzheimer's disease CX3CL1 CXCR3 CX3CL1-004 ENST00000564948
SRR19243471 Alzheimer's disease CX3CL1 CCR3 CX3CL1-004 ENST00000564948
SRR19243472 Alzheimer's disease CX3CL1 CCR2 CX3CL1-004 ENST00000564948
SRR19243472 Alzheimer's disease CX3CL1 CCR5 CX3CL1-004 ENST00000564948
SRR19243472 Alzheimer's disease CX3CL1 CXCR1 CX3CL1-004 ENST00000564948
SRR19243472 Alzheimer's disease CX3CL1 CCR1 CX3CL1-004 ENST00000564948
SRR19243472 Alzheimer's disease CX3CL1 CXCR2 CX3CL1-004 ENST00000564948
SRR19243472 Alzheimer's disease CX3CL1 CX3CR1 CX3CL1-004 ENST00000564948
SRR19243472 Alzheimer's disease CX3CL1 CXCR3 CX3CL1-004 ENST00000564948
SRR19243472 Alzheimer's disease CX3CL1 CCR3 CX3CL1-004 ENST00000564948
SRR19243476 Alzheimer's disease CX3CL1 CCR2 CX3CL1-004 ENST00000564948
SRR19243476 Alzheimer's disease CX3CL1 CCR5 CX3CL1-004 ENST00000564948
SRR19243476 Alzheimer's disease CX3CL1 CXCR1 CX3CL1-004 ENST00000564948
SRR19243476 Alzheimer's disease CX3CL1 CCR1 CX3CL1-004 ENST00000564948
SRR19243476 Alzheimer's disease CX3CL1 CXCR2 CX3CL1-004 ENST00000564948
SRR19243476 Alzheimer's disease CX3CL1 CX3CR1 CX3CL1-004 ENST00000564948
SRR19243476 Alzheimer's disease CX3CL1 CXCR3 CX3CL1-004 ENST00000564948
SRR19243476 Alzheimer's disease CX3CL1 CCR3 CX3CL1-004 ENST00000564948
Interaction losses with Clinvar proteins
Gene Name
CCR5
CX3CR1
CXCR1
CXCR2