CanIsoNet

Gene Name:

Transcript ID:
Transcript Name:
dMDT Interaction Network

Protein interaction losses due to MDT switch
*only proteins having domain-domain interaction information are taken into consideration
Number of Total Interaction:
Number of Lost Interaction:
Gene Name Interaction Lost Lost Domain (Region) Lost Domain - Domain Interaction
SMG1 SMG1-RPTOR PI3_PI4_kinase(2150-2426) PI3_PI4_kinase(2150-2426) - WD40
SMG1 SMG1-MLST8 PI3_PI4_kinase(2150-2426) PI3_PI4_kinase(2150-2426) - WD40

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
Sample ID Disease Type Gene Name 1 Gene Name 2 Transcript Name dMDT
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA SMG1 RPTOR SMG1-013 ENST00000569122
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA SMG1 MLST8 SMG1-013 ENST00000569122
Interaction losses with Clinvar proteins
Gene Name