CanIsoNet

Gene Name:

Transcript ID:
Transcript Name:
dMDT Interaction Network

Protein interaction lost due to MDT switch
*only proteins having domain-domain interaction information are taken into consideration
Number of Total Interaction:
Number of Lost Interaction:
Gene Name Interaction Lost Lost Domain (Region) Lost Domain<-->Domain Interaction
APBB1IP APBB1IP-CSK PH(312-416) PH(312-416)--SH3_1
APBB1IP APBB1IP-CRK PH(312-416) PH(312-416)--SH3_1
APBB1IP APBB1IP-BCAR1 PH(312-416) PH(312-416)--SH3_1
APBB1IP APBB1IP-AKT1 PH(312-416) PH(312-416)--Pkinase
APBB1IP APBB1IP-PDPK1 PH(312-416) PH(312-416)--Pkinase
APBB1IP APBB1IP-RAP1B PH(312-416) PH(312-416)--Ras
APBB1IP APBB1IP-RAP1A PH(312-416) PH(312-416)--Ras
APBB1IP APBB1IP-RASGRP1 PH(312-416) PH(312-416)--C1_1
APBB1IP APBB1IP-RASGRP2 PH(312-416) PH(312-416)--C1_1
APBB1IP APBB1IP-SKAP1 PH(312-416) PH(312-416)--PH
APBB1IP APBB1IP-SOS1 PH(312-416) PH(312-416)--PH
APBB1IP APBB1IP-RAPGEF4 PH(312-416) PH(312-416)--RA
APBB1IP APBB1IP-TLN1 PH(312-416) PH(312-416)--IRS
APBB1IP APBB1IP-PTK2 PH(312-416) PH(312-416)--Pkinase_Tyr
APBB1IP APBB1IP-SYK PH(312-416) PH(312-416)--Pkinase_Tyr

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Protein Interaction Lost due to the MDT switch in all disease types
Sample ID Disease Type Gene Name 1 Gene Name 2 Transcript Name dMDT
39178b5c-3a32-4e85-a2ca-a4e06097718a Lymph-CLL APBB1IP CSK APBB1IP-001 ENST00000356785
39178b5c-3a32-4e85-a2ca-a4e06097718a Lymph-CLL APBB1IP CRK APBB1IP-001 ENST00000356785
39178b5c-3a32-4e85-a2ca-a4e06097718a Lymph-CLL APBB1IP BCAR1 APBB1IP-001 ENST00000356785
39178b5c-3a32-4e85-a2ca-a4e06097718a Lymph-CLL APBB1IP AKT1 APBB1IP-001 ENST00000356785
39178b5c-3a32-4e85-a2ca-a4e06097718a Lymph-CLL APBB1IP PDPK1 APBB1IP-001 ENST00000356785
39178b5c-3a32-4e85-a2ca-a4e06097718a Lymph-CLL APBB1IP RAP1B APBB1IP-001 ENST00000356785
39178b5c-3a32-4e85-a2ca-a4e06097718a Lymph-CLL APBB1IP RAP1A APBB1IP-001 ENST00000356785
39178b5c-3a32-4e85-a2ca-a4e06097718a Lymph-CLL APBB1IP RASGRP1 APBB1IP-001 ENST00000356785
39178b5c-3a32-4e85-a2ca-a4e06097718a Lymph-CLL APBB1IP RASGRP2 APBB1IP-001 ENST00000356785
39178b5c-3a32-4e85-a2ca-a4e06097718a Lymph-CLL APBB1IP SKAP1 APBB1IP-001 ENST00000356785
39178b5c-3a32-4e85-a2ca-a4e06097718a Lymph-CLL APBB1IP SOS1 APBB1IP-001 ENST00000356785
39178b5c-3a32-4e85-a2ca-a4e06097718a Lymph-CLL APBB1IP RAPGEF4 APBB1IP-001 ENST00000356785
39178b5c-3a32-4e85-a2ca-a4e06097718a Lymph-CLL APBB1IP TLN1 APBB1IP-001 ENST00000356785
39178b5c-3a32-4e85-a2ca-a4e06097718a Lymph-CLL APBB1IP PTK2 APBB1IP-001 ENST00000356785
39178b5c-3a32-4e85-a2ca-a4e06097718a Lymph-CLL APBB1IP SYK APBB1IP-001 ENST00000356785
70c76dd2-e52f-4caa-9e73-0c730f8e408a Lymph-CLL APBB1IP CSK APBB1IP-001 ENST00000356785
70c76dd2-e52f-4caa-9e73-0c730f8e408a Lymph-CLL APBB1IP CRK APBB1IP-001 ENST00000356785
70c76dd2-e52f-4caa-9e73-0c730f8e408a Lymph-CLL APBB1IP BCAR1 APBB1IP-001 ENST00000356785
70c76dd2-e52f-4caa-9e73-0c730f8e408a Lymph-CLL APBB1IP AKT1 APBB1IP-001 ENST00000356785
70c76dd2-e52f-4caa-9e73-0c730f8e408a Lymph-CLL APBB1IP PDPK1 APBB1IP-001 ENST00000356785
70c76dd2-e52f-4caa-9e73-0c730f8e408a Lymph-CLL APBB1IP RAP1B APBB1IP-001 ENST00000356785
70c76dd2-e52f-4caa-9e73-0c730f8e408a Lymph-CLL APBB1IP RAP1A APBB1IP-001 ENST00000356785
70c76dd2-e52f-4caa-9e73-0c730f8e408a Lymph-CLL APBB1IP RASGRP1 APBB1IP-001 ENST00000356785
70c76dd2-e52f-4caa-9e73-0c730f8e408a Lymph-CLL APBB1IP RASGRP2 APBB1IP-001 ENST00000356785
70c76dd2-e52f-4caa-9e73-0c730f8e408a Lymph-CLL APBB1IP SKAP1 APBB1IP-001 ENST00000356785
70c76dd2-e52f-4caa-9e73-0c730f8e408a Lymph-CLL APBB1IP SOS1 APBB1IP-001 ENST00000356785
70c76dd2-e52f-4caa-9e73-0c730f8e408a Lymph-CLL APBB1IP RAPGEF4 APBB1IP-001 ENST00000356785
70c76dd2-e52f-4caa-9e73-0c730f8e408a Lymph-CLL APBB1IP TLN1 APBB1IP-001 ENST00000356785
70c76dd2-e52f-4caa-9e73-0c730f8e408a Lymph-CLL APBB1IP PTK2 APBB1IP-001 ENST00000356785
70c76dd2-e52f-4caa-9e73-0c730f8e408a Lymph-CLL APBB1IP SYK APBB1IP-001 ENST00000356785
d2b399f3-b10b-44ee-b141-4d746b67fd93 Lymph-CLL APBB1IP CSK APBB1IP-001 ENST00000356785
d2b399f3-b10b-44ee-b141-4d746b67fd93 Lymph-CLL APBB1IP CRK APBB1IP-001 ENST00000356785
d2b399f3-b10b-44ee-b141-4d746b67fd93 Lymph-CLL APBB1IP BCAR1 APBB1IP-001 ENST00000356785
d2b399f3-b10b-44ee-b141-4d746b67fd93 Lymph-CLL APBB1IP AKT1 APBB1IP-001 ENST00000356785
d2b399f3-b10b-44ee-b141-4d746b67fd93 Lymph-CLL APBB1IP PDPK1 APBB1IP-001 ENST00000356785
d2b399f3-b10b-44ee-b141-4d746b67fd93 Lymph-CLL APBB1IP RAP1B APBB1IP-001 ENST00000356785
d2b399f3-b10b-44ee-b141-4d746b67fd93 Lymph-CLL APBB1IP RAP1A APBB1IP-001 ENST00000356785
d2b399f3-b10b-44ee-b141-4d746b67fd93 Lymph-CLL APBB1IP RASGRP1 APBB1IP-001 ENST00000356785
d2b399f3-b10b-44ee-b141-4d746b67fd93 Lymph-CLL APBB1IP RASGRP2 APBB1IP-001 ENST00000356785
d2b399f3-b10b-44ee-b141-4d746b67fd93 Lymph-CLL APBB1IP SKAP1 APBB1IP-001 ENST00000356785
d2b399f3-b10b-44ee-b141-4d746b67fd93 Lymph-CLL APBB1IP SOS1 APBB1IP-001 ENST00000356785
d2b399f3-b10b-44ee-b141-4d746b67fd93 Lymph-CLL APBB1IP RAPGEF4 APBB1IP-001 ENST00000356785
d2b399f3-b10b-44ee-b141-4d746b67fd93 Lymph-CLL APBB1IP TLN1 APBB1IP-001 ENST00000356785
d2b399f3-b10b-44ee-b141-4d746b67fd93 Lymph-CLL APBB1IP PTK2 APBB1IP-001 ENST00000356785
d2b399f3-b10b-44ee-b141-4d746b67fd93 Lymph-CLL APBB1IP SYK APBB1IP-001 ENST00000356785
Protein Interaction Lost with Proteins annotated in Clinvar
Gene Name
AKT1
RASGRP1
RASGRP2
SOS1
SYK