CanIsoNet

Gene Name:

Transcript ID:
Transcript Name:
dMDT Interaction Network

Protein interaction losses due to MDT switch
*only proteins having domain-domain interaction information are taken into consideration
Number of Total Interaction:
Number of Lost Interaction:
Gene Name Interaction Lost Lost Domain (Region) Lost Domain - Domain Interaction
ARHGEF5 ARHGEF5-RAC1 RhoGEF(1180-1356) RhoGEF(1180-1356) - Ras
ARHGEF5 ARHGEF5-ARHGAP5 RhoGEF(1180-1356) RhoGEF(1180-1356) - Ras
ARHGEF5 ARHGEF5-RHOA RhoGEF(1180-1356) RhoGEF(1180-1356) - Ras
ARHGEF5 ARHGEF5-GNA12 RhoGEF(1180-1356) RhoGEF(1180-1356) - G-alpha
ARHGEF5 ARHGEF5-GNAQ RhoGEF(1180-1356) RhoGEF(1180-1356) - G-alpha
ARHGEF5 ARHGEF5-GNA13 RhoGEF(1180-1356) RhoGEF(1180-1356) - G-alpha

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Interaction losses with Clinvar proteins
Gene Name
GNAQ
RAC1
RHOA