dMDT Interaction Network
Protein interaction losses due to MDT switch
| Gene Name | Interaction Lost | Lost Domain (Region) | Lost Domain - Domain Interaction |
|---|---|---|---|
| ATF1 | ATF1-FOS | bZIP_1(212-268) | bZIP_1(212-268) - bZIP_1 |
| ATF1 | ATF1-JUN | bZIP_1(212-268) | bZIP_1(212-268) - bZIP_1 |
| ATF1 | ATF1-CREBBP | pKID(43-83) | pKID(43-83) - KIX |
Network Density Score: %
The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
| Sample ID | Disease Type | Gene Name 1 | Gene Name 2 | Transcript Name | dMDT |
|---|---|---|---|---|---|
| 6ccc37a2-f073-4050-bfcd-de106d86236b | Lung.Lung-SCC | ATF1 | FOS | ATF1-005 | ENST00000549612 |
| 6ccc37a2-f073-4050-bfcd-de106d86236b | Lung.Lung-SCC | ATF1 | JUN | ATF1-005 | ENST00000549612 |
| 6ccc37a2-f073-4050-bfcd-de106d86236b | Lung.Lung-SCC | ATF1 | CREBBP | ATF1-005 | ENST00000549612 |
Interaction losses with Clinvar proteins
| Gene Name |
|---|
| CREBBP |