CanIsoNet

Gene Name:

Transcript ID:
Transcript Name:
dMDT Interaction Network

Protein interaction losses due to MDT switch
*only proteins having domain-domain interaction information are taken into consideration
Number of Total Interaction:
Number of Lost Interaction:
Gene Name Interaction Lost Lost Domain (Region) Lost Domain - Domain Interaction
ATM ATM-ABL1 PI3_PI4_kinase(2714-2961) PI3_PI4_kinase(2714-2961) - SH2
ATM ATM-RFWD2 PI3_PI4_kinase(2714-2961) PI3_PI4_kinase(2714-2961) - WD40
ATM ATM-PRKDC PI3_PI4_kinase(2714-2961) PI3_PI4_kinase(2714-2961) - PI3_PI4_kinase
ATM ATM-ATR PI3_PI4_kinase(2714-2961) PI3_PI4_kinase(2714-2961) - PI3_PI4_kinase
ATM ATM-BARD1 FAT(2097-2488) FAT(2097-2488) - Ank_2
ATM ATM-CDKN2D FAT(2097-2488) FAT(2097-2488) - Ank_2

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Interaction losses with Clinvar proteins
Gene Name
ABL1
ATM
ATR
BARD1
PRKDC