CanIsoNet

Gene Name:

Transcript ID:
Transcript Name:
dMDT Interaction Network

Protein interaction losses due to MDT switch
*only proteins having domain-domain interaction information are taken into consideration
Number of Total Interaction:
Number of Lost Interaction:
Gene Name Interaction Lost Lost Domain (Region) Lost Domain - Domain Interaction
BRCA1 BRCA1-TOPBP1 BRCT(1778-1863) BRCT(1778-1863) - BRCT

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
Sample ID Disease Type Gene Name 1 Gene Name 2 Transcript Name dMDT
d398a0c1-d873-49c1-b657-0c1d7121f3aa Pancreas.Panc-AdenoCA BRCA1 TOPBP1 BRCA1-017 ENST00000476777
Interaction losses with Clinvar proteins
Gene Name
BRCA1