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Specific dMDT
Disease-type-specific MDTs
Lost Domain in dMDT
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Gene Name:
Transcript ID:
Transcript Name:
dMDT Interaction Network
Protein interaction losses due to MDT switch
*only proteins having domain-domain interaction information are taken into consideration
Number of Total Interaction:
Number of Lost Interaction:
Gene Name
Interaction Lost
Lost Domain (Region)
Lost Domain - Domain Interaction
BRCA1
BRCA1
-TOPBP1
BRCT
(1778-1863)
BRCT
(1778-1863) -
BRCT
Network Density Score:
%
The local network of this protein has more interaction than
% of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
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Sample ID
Disease Type
Gene Name 1
Gene Name 2
Transcript Name
dMDT
d398a0c1-d873-49c1-b657-0c1d7121f3aa
Pancreas.Panc-AdenoCA
BRCA1
TOPBP1
BRCA1-017
ENST00000476777
Interaction losses with Clinvar proteins
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Gene Name
BRCA1