CanIsoNet

Gene Name:

Transcript ID:
Transcript Name:
dMDT Interaction Network

Protein interaction lost due to MDT switch
*only proteins having domain-domain interaction information are taken into consideration
Number of Total Interaction:
Number of Lost Interaction:
Gene Name Interaction Lost Lost Domain (Region) Lost Domain<-->Domain Interaction
C3 C3-CFHR5 A2M(770-866) A2M(770-866)--Sushi
C3 C3-CD46 A2M(770-866) A2M(770-866)--Sushi
C3 C3-CFHR1 A2M(770-866) A2M(770-866)--Sushi
C3 C3-CD55 A2M(770-866) A2M(770-866)--Sushi
C3 C3-CR1 A2M(770-866) A2M(770-866)--Sushi
C3 C3-CR2 A2M(770-866) A2M(770-866)--Sushi
C3 C3-CFHR4 A2M(770-866) A2M(770-866)--Sushi
C3 C3-CFHR3 A2M(770-866) A2M(770-866)--Sushi
C3 C3-CFH A2M(770-866) A2M(770-866)--Sushi
C3 C3-CFB A2M(770-866) A2M(770-866)--Sushi
C3 C3-C5 A2M(770-866) A2M(770-866)--A2M_N
C3 C3-C4A A2M(770-866) A2M(770-866)--A2M_N
C3 C3-VSIG4 A2M(770-866) A2M(770-866)--V-set
C3 C3-ITGAX NTR(1534-1644) NTR(1534-1644)--VWA
C3 C3-ITGAM NTR(1534-1644) NTR(1534-1644)--VWA
C3 C3-PLG A2M_N(129-224) A2M_N(129-224)--Trypsin
C3 C3-CFD A2M_N(129-224) A2M_N(129-224)--Trypsin
C3 C3-CFI A2M_N(129-224) A2M_N(129-224)--Trypsin
C3 C3-CFP A2M_comp(1051-1283) A2M_comp(1051-1283)--TSP_1
C3 None None

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Protein Interaction Lost due to the MDT switch in all disease types
Sample ID Disease Type Gene Name 1 Gene Name 2 Transcript Name dMDT
312ea080-3831-453d-aa8c-e466192c8309 Bladder-TCC C3 CFHR5 C3-003 ENST00000600744
312ea080-3831-453d-aa8c-e466192c8309 Bladder-TCC C3 CD46 C3-003 ENST00000600744
312ea080-3831-453d-aa8c-e466192c8309 Bladder-TCC C3 CFHR1 C3-003 ENST00000600744
312ea080-3831-453d-aa8c-e466192c8309 Bladder-TCC C3 CD55 C3-003 ENST00000600744
312ea080-3831-453d-aa8c-e466192c8309 Bladder-TCC C3 CR1 C3-003 ENST00000600744
312ea080-3831-453d-aa8c-e466192c8309 Bladder-TCC C3 CR2 C3-003 ENST00000600744
312ea080-3831-453d-aa8c-e466192c8309 Bladder-TCC C3 CFHR4 C3-003 ENST00000600744
312ea080-3831-453d-aa8c-e466192c8309 Bladder-TCC C3 CFHR3 C3-003 ENST00000600744
312ea080-3831-453d-aa8c-e466192c8309 Bladder-TCC C3 CFH C3-003 ENST00000600744
312ea080-3831-453d-aa8c-e466192c8309 Bladder-TCC C3 CFB C3-003 ENST00000600744
312ea080-3831-453d-aa8c-e466192c8309 Bladder-TCC C3 C5 C3-003 ENST00000600744
312ea080-3831-453d-aa8c-e466192c8309 Bladder-TCC C3 C4A C3-003 ENST00000600744
312ea080-3831-453d-aa8c-e466192c8309 Bladder-TCC C3 VSIG4 C3-003 ENST00000600744
312ea080-3831-453d-aa8c-e466192c8309 Bladder-TCC C3 ITGAX C3-003 ENST00000600744
312ea080-3831-453d-aa8c-e466192c8309 Bladder-TCC C3 ITGAM C3-003 ENST00000600744
312ea080-3831-453d-aa8c-e466192c8309 Bladder-TCC C3 PLG C3-003 ENST00000600744
312ea080-3831-453d-aa8c-e466192c8309 Bladder-TCC C3 CFD C3-003 ENST00000600744
312ea080-3831-453d-aa8c-e466192c8309 Bladder-TCC C3 CFI C3-003 ENST00000600744
312ea080-3831-453d-aa8c-e466192c8309 Bladder-TCC C3 CFP C3-003 ENST00000600744
48645bef-8e98-4a16-9de5-c43cdeca8b95 Bone-Leiomyo C3 CFHR5 C3-003 ENST00000600744
48645bef-8e98-4a16-9de5-c43cdeca8b95 Bone-Leiomyo C3 CD46 C3-003 ENST00000600744
48645bef-8e98-4a16-9de5-c43cdeca8b95 Bone-Leiomyo C3 CFHR1 C3-003 ENST00000600744
48645bef-8e98-4a16-9de5-c43cdeca8b95 Bone-Leiomyo C3 CD55 C3-003 ENST00000600744
48645bef-8e98-4a16-9de5-c43cdeca8b95 Bone-Leiomyo C3 CR1 C3-003 ENST00000600744
48645bef-8e98-4a16-9de5-c43cdeca8b95 Bone-Leiomyo C3 CR2 C3-003 ENST00000600744
48645bef-8e98-4a16-9de5-c43cdeca8b95 Bone-Leiomyo C3 CFHR4 C3-003 ENST00000600744
48645bef-8e98-4a16-9de5-c43cdeca8b95 Bone-Leiomyo C3 CFHR3 C3-003 ENST00000600744
48645bef-8e98-4a16-9de5-c43cdeca8b95 Bone-Leiomyo C3 CFH C3-003 ENST00000600744
48645bef-8e98-4a16-9de5-c43cdeca8b95 Bone-Leiomyo C3 CFB C3-003 ENST00000600744
48645bef-8e98-4a16-9de5-c43cdeca8b95 Bone-Leiomyo C3 C5 C3-003 ENST00000600744
48645bef-8e98-4a16-9de5-c43cdeca8b95 Bone-Leiomyo C3 C4A C3-003 ENST00000600744
48645bef-8e98-4a16-9de5-c43cdeca8b95 Bone-Leiomyo C3 VSIG4 C3-003 ENST00000600744
48645bef-8e98-4a16-9de5-c43cdeca8b95 Bone-Leiomyo C3 ITGAX C3-003 ENST00000600744
48645bef-8e98-4a16-9de5-c43cdeca8b95 Bone-Leiomyo C3 ITGAM C3-003 ENST00000600744
48645bef-8e98-4a16-9de5-c43cdeca8b95 Bone-Leiomyo C3 PLG C3-003 ENST00000600744
48645bef-8e98-4a16-9de5-c43cdeca8b95 Bone-Leiomyo C3 CFD C3-003 ENST00000600744
48645bef-8e98-4a16-9de5-c43cdeca8b95 Bone-Leiomyo C3 CFI C3-003 ENST00000600744
48645bef-8e98-4a16-9de5-c43cdeca8b95 Bone-Leiomyo C3 CFP C3-003 ENST00000600744
23f183f4-735e-4361-940c-e09edd6f2d2a Skin-Melanoma C3 None C3-003 ENST00000600744
2988e553-2978-4d25-b6b0-0c2d2147c5d8 Skin-Melanoma C3 None C3-003 ENST00000600744
7eb0de2d-f2b7-4bbd-bfdf-38f9205dfcd9 Skin-Melanoma C3 None C3-003 ENST00000600744
dca3aac8-2cc3-41fb-b030-0b0084ca6217 Skin-Melanoma C3 None C3-003 ENST00000600744
18dd389b-b0b7-43f7-877f-0fb8e3471af0 Thy-AdenoCA C3 CFHR5 C3-003 ENST00000600744
18dd389b-b0b7-43f7-877f-0fb8e3471af0 Thy-AdenoCA C3 CD46 C3-003 ENST00000600744
18dd389b-b0b7-43f7-877f-0fb8e3471af0 Thy-AdenoCA C3 CFHR1 C3-003 ENST00000600744
18dd389b-b0b7-43f7-877f-0fb8e3471af0 Thy-AdenoCA C3 CD55 C3-003 ENST00000600744
18dd389b-b0b7-43f7-877f-0fb8e3471af0 Thy-AdenoCA C3 CR1 C3-003 ENST00000600744
18dd389b-b0b7-43f7-877f-0fb8e3471af0 Thy-AdenoCA C3 CR2 C3-003 ENST00000600744
18dd389b-b0b7-43f7-877f-0fb8e3471af0 Thy-AdenoCA C3 CFHR4 C3-003 ENST00000600744
18dd389b-b0b7-43f7-877f-0fb8e3471af0 Thy-AdenoCA C3 CFHR3 C3-003 ENST00000600744
18dd389b-b0b7-43f7-877f-0fb8e3471af0 Thy-AdenoCA C3 CFH C3-003 ENST00000600744
18dd389b-b0b7-43f7-877f-0fb8e3471af0 Thy-AdenoCA C3 CFB C3-003 ENST00000600744
18dd389b-b0b7-43f7-877f-0fb8e3471af0 Thy-AdenoCA C3 C5 C3-003 ENST00000600744
18dd389b-b0b7-43f7-877f-0fb8e3471af0 Thy-AdenoCA C3 C4A C3-003 ENST00000600744
18dd389b-b0b7-43f7-877f-0fb8e3471af0 Thy-AdenoCA C3 VSIG4 C3-003 ENST00000600744
18dd389b-b0b7-43f7-877f-0fb8e3471af0 Thy-AdenoCA C3 ITGAX C3-003 ENST00000600744
18dd389b-b0b7-43f7-877f-0fb8e3471af0 Thy-AdenoCA C3 ITGAM C3-003 ENST00000600744
18dd389b-b0b7-43f7-877f-0fb8e3471af0 Thy-AdenoCA C3 PLG C3-003 ENST00000600744
18dd389b-b0b7-43f7-877f-0fb8e3471af0 Thy-AdenoCA C3 CFD C3-003 ENST00000600744
18dd389b-b0b7-43f7-877f-0fb8e3471af0 Thy-AdenoCA C3 CFI C3-003 ENST00000600744
18dd389b-b0b7-43f7-877f-0fb8e3471af0 Thy-AdenoCA C3 CFP C3-003 ENST00000600744
4c1d10e6-c86a-4139-94f6-185a97377550 Thy-AdenoCA C3 CFHR5 C3-003 ENST00000600744
4c1d10e6-c86a-4139-94f6-185a97377550 Thy-AdenoCA C3 CD46 C3-003 ENST00000600744
4c1d10e6-c86a-4139-94f6-185a97377550 Thy-AdenoCA C3 CFHR1 C3-003 ENST00000600744
4c1d10e6-c86a-4139-94f6-185a97377550 Thy-AdenoCA C3 CD55 C3-003 ENST00000600744
4c1d10e6-c86a-4139-94f6-185a97377550 Thy-AdenoCA C3 CR1 C3-003 ENST00000600744
4c1d10e6-c86a-4139-94f6-185a97377550 Thy-AdenoCA C3 CR2 C3-003 ENST00000600744
4c1d10e6-c86a-4139-94f6-185a97377550 Thy-AdenoCA C3 CFHR4 C3-003 ENST00000600744
4c1d10e6-c86a-4139-94f6-185a97377550 Thy-AdenoCA C3 CFHR3 C3-003 ENST00000600744
4c1d10e6-c86a-4139-94f6-185a97377550 Thy-AdenoCA C3 CFH C3-003 ENST00000600744
4c1d10e6-c86a-4139-94f6-185a97377550 Thy-AdenoCA C3 CFB C3-003 ENST00000600744
4c1d10e6-c86a-4139-94f6-185a97377550 Thy-AdenoCA C3 C5 C3-003 ENST00000600744
4c1d10e6-c86a-4139-94f6-185a97377550 Thy-AdenoCA C3 C4A C3-003 ENST00000600744
4c1d10e6-c86a-4139-94f6-185a97377550 Thy-AdenoCA C3 VSIG4 C3-003 ENST00000600744
4c1d10e6-c86a-4139-94f6-185a97377550 Thy-AdenoCA C3 ITGAX C3-003 ENST00000600744
4c1d10e6-c86a-4139-94f6-185a97377550 Thy-AdenoCA C3 ITGAM C3-003 ENST00000600744
4c1d10e6-c86a-4139-94f6-185a97377550 Thy-AdenoCA C3 PLG C3-003 ENST00000600744
4c1d10e6-c86a-4139-94f6-185a97377550 Thy-AdenoCA C3 CFD C3-003 ENST00000600744
4c1d10e6-c86a-4139-94f6-185a97377550 Thy-AdenoCA C3 CFI C3-003 ENST00000600744
4c1d10e6-c86a-4139-94f6-185a97377550 Thy-AdenoCA C3 CFP C3-003 ENST00000600744
Protein Interaction Lost with Proteins annotated in Clinvar
Gene Name
C4A
C5
CD46
CD55
CFB
CFD
CFH
CFHR1
CFHR3
CFHR4
CFHR5
CFI
CFP
CR1
CR2
PLG