CanIsoNet

Gene Name:

Transcript ID:
Transcript Name:
dMDT Interaction Network

Protein interaction losses due to MDT switch
*only proteins having domain-domain interaction information are taken into consideration
Number of Total Interaction:
Number of Lost Interaction:
Gene Name Interaction Lost Lost Domain (Region) Lost Domain - Domain Interaction
CD14 CD14-TLR1 LRR_1(298-341) LRR_1(298-341) - LRR_1
CD14 CD14-LY86 LRR_1(298-341) LRR_1(298-341) - E1_DerP2_DerF2
CD14 CD14-LY96 LRR_1(298-341) LRR_1(298-341) - E1_DerP2_DerF2
CD14 CD14-TLR4 LRR_1(298-341) LRR_1(298-341) - LRR_6
CD14 CD14-CD180 LRR_1(298-341) LRR_1(298-341) - LRR_8
CD14 CD14-TLR2 LRR_1(298-341) LRR_1(298-341) - LRR_8
CD14 CD14-TLR6 LRR_1(298-341) LRR_1(298-341) - LRR_8

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
Sample ID Disease Type Gene Name 1 Gene Name 2 Transcript Name dMDT
SRR19243443 Alzheimer's disease CD14 TLR1 CD14-004 ENST00000519715
SRR19243443 Alzheimer's disease CD14 LY86 CD14-004 ENST00000519715
SRR19243443 Alzheimer's disease CD14 LY96 CD14-004 ENST00000519715
SRR19243443 Alzheimer's disease CD14 TLR4 CD14-004 ENST00000519715
SRR19243443 Alzheimer's disease CD14 CD180 CD14-004 ENST00000519715
SRR19243443 Alzheimer's disease CD14 TLR2 CD14-004 ENST00000519715
SRR19243443 Alzheimer's disease CD14 TLR6 CD14-004 ENST00000519715
SRR19243448 Alzheimer's disease CD14 TLR1 CD14-004 ENST00000519715
SRR19243448 Alzheimer's disease CD14 LY86 CD14-004 ENST00000519715
SRR19243448 Alzheimer's disease CD14 LY96 CD14-004 ENST00000519715
SRR19243448 Alzheimer's disease CD14 TLR4 CD14-004 ENST00000519715
SRR19243448 Alzheimer's disease CD14 CD180 CD14-004 ENST00000519715
SRR19243448 Alzheimer's disease CD14 TLR2 CD14-004 ENST00000519715
SRR19243448 Alzheimer's disease CD14 TLR6 CD14-004 ENST00000519715
SRR19243464 Alzheimer's disease CD14 TLR1 CD14-004 ENST00000519715
SRR19243464 Alzheimer's disease CD14 LY86 CD14-004 ENST00000519715
SRR19243464 Alzheimer's disease CD14 LY96 CD14-004 ENST00000519715
SRR19243464 Alzheimer's disease CD14 TLR4 CD14-004 ENST00000519715
SRR19243464 Alzheimer's disease CD14 CD180 CD14-004 ENST00000519715
SRR19243464 Alzheimer's disease CD14 TLR2 CD14-004 ENST00000519715
SRR19243464 Alzheimer's disease CD14 TLR6 CD14-004 ENST00000519715
SRR19243470 Alzheimer's disease CD14 TLR1 CD14-004 ENST00000519715
SRR19243470 Alzheimer's disease CD14 LY86 CD14-004 ENST00000519715
SRR19243470 Alzheimer's disease CD14 LY96 CD14-004 ENST00000519715
SRR19243470 Alzheimer's disease CD14 TLR4 CD14-004 ENST00000519715
SRR19243470 Alzheimer's disease CD14 CD180 CD14-004 ENST00000519715
SRR19243470 Alzheimer's disease CD14 TLR2 CD14-004 ENST00000519715
SRR19243470 Alzheimer's disease CD14 TLR6 CD14-004 ENST00000519715
Interaction losses with Clinvar proteins
Gene Name
TLR1
TLR2