dMDT Interaction Network
Protein interaction losses due to MDT switch
| Gene Name | Interaction Lost | Lost Domain (Region) | Lost Domain - Domain Interaction |
|---|---|---|---|
| CDK4 | None | None | None |
| CDK4 | CDK4-PSMD10 | Pkinase(7-295) | Pkinase(7-295) - Ank |
| CDK4 | CDK4-CDKN2A | Pkinase(7-295) | Pkinase(7-295) - Ank |
| CDK4 | CDK4-CDK13 | Pkinase(7-295) | Pkinase(7-295) - Pkinase |
| CDK4 | CDK4-CDC7 | Pkinase(7-295) | Pkinase(7-295) - Pkinase |
| CDK4 | CDK4-CDK7 | Pkinase(7-295) | Pkinase(7-295) - Pkinase |
| CDK4 | CDK4-CDK6 | Pkinase(7-295) | Pkinase(7-295) - Pkinase |
| CDK4 | CDK4-CDK14 | Pkinase(7-295) | Pkinase(7-295) - Pkinase |
| CDK4 | CDK4-CDK2 | Pkinase(7-295) | Pkinase(7-295) - Pkinase |
| CDK4 | CDK4-CDK19 | Pkinase(7-295) | Pkinase(7-295) - Pkinase |
| CDK4 | CDK4-CDK8 | Pkinase(7-295) | Pkinase(7-295) - Pkinase |
| CDK4 | CDK4-CDK1 | Pkinase(7-295) | Pkinase(7-295) - Pkinase |
| CDK4 | CDK4-CDK3 | Pkinase(7-295) | Pkinase(7-295) - Pkinase |
| CDK4 | CDK4-CDK5 | Pkinase(7-295) | Pkinase(7-295) - Pkinase |
| CDK4 | CDK4-PPARGC1A | Pkinase(7-295) | Pkinase(7-295) - RRM_1 |
| CDK4 | CDK4-CCND1 | Pkinase(7-295) | Pkinase(7-295) - Cyclin_N |
| CDK4 | CDK4-CCNA1 | Pkinase(7-295) | Pkinase(7-295) - Cyclin_N |
| CDK4 | CDK4-CCNB1 | Pkinase(7-295) | Pkinase(7-295) - Cyclin_N |
| CDK4 | CDK4-CCNH | Pkinase(7-295) | Pkinase(7-295) - Cyclin_N |
| CDK4 | CDK4-CCND2 | Pkinase(7-295) | Pkinase(7-295) - Cyclin_N |
| CDK4 | CDK4-CCNE1 | Pkinase(7-295) | Pkinase(7-295) - Cyclin_N |
| CDK4 | CDK4-CCNA2 | Pkinase(7-295) | Pkinase(7-295) - Cyclin_N |
| CDK4 | CDK4-CCNB2 | Pkinase(7-295) | Pkinase(7-295) - Cyclin_N |
| CDK4 | CDK4-CCNE2 | Pkinase(7-295) | Pkinase(7-295) - Cyclin_N |
| CDK4 | CDK4-CCND3 | Pkinase(7-295) | Pkinase(7-295) - Cyclin_N |
| CDK4 | CDK4-CCNY | Pkinase(7-295) | Pkinase(7-295) - Cyclin_N |
| CDK4 | CDK4-CCNF | Pkinase(7-295) | Pkinase(7-295) - Cyclin_N |
| CDK4 | CDK4-CCNC | Pkinase(7-295) | Pkinase(7-295) - Cyclin_N |
| CDK4 | CDK4-HSP90AA1 | Pkinase(7-295) | Pkinase(7-295) - HSP90 |
| CDK4 | CDK4-UBC | Pkinase(7-295) | Pkinase(7-295) - ubiquitin |
| CDK4 | CDK4-NBN | Pkinase(7-295) | Pkinase(7-295) - FHA |
| CDK4 | CDK4-CDC25A | Pkinase(7-295) | Pkinase(7-295) - Rhodanese |
| CDK4 | CDK4-CDC25C | Pkinase(7-295) | Pkinase(7-295) - Rhodanese |
| CDK4 | CDK4-TNRC6C | Pkinase(7-295) | Pkinase(7-295) - UBA |
| CDK4 | CDK4-CDKN1B | Pkinase(7-295) | Pkinase(7-295) - CDI |
| CDK4 | CDK4-CDKN1A | Pkinase(7-295) | Pkinase(7-295) - CDI |
| CDK4 | CDK4-CDKN1C | Pkinase(7-295) | Pkinase(7-295) - CDI |
| CDK4 | CDK4-CDC37 | Pkinase(7-295) | Pkinase(7-295) - CDC37_N |
| CDK4 | CDK4-ABL1 | Pkinase(7-295) | Pkinase(7-295) - Pkinase_Tyr |
| CDK4 | CDK4-CDKN2C | Pkinase(7-295) | Pkinase(7-295) - Ank_2 |
| CDK4 | CDK4-CDKN2B | Pkinase(7-295) | Pkinase(7-295) - Ank_2 |
| CDK4 | CDK4-NOTCH1 | Pkinase(7-295) | Pkinase(7-295) - Ank_2 |
| CDK4 | CDK4-CDKN2D | Pkinase(7-295) | Pkinase(7-295) - Ank_2 |
Network Density Score: %
The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch