CanIsoNet

Gene Name:

Transcript ID:
Transcript Name:
dMDT Interaction Network

Protein interaction losses due to MDT switch
*only proteins having domain-domain interaction information are taken into consideration
Number of Total Interaction:
Number of Lost Interaction:
Gene Name Interaction Lost Lost Domain (Region) Lost Domain - Domain Interaction
CHFR CHFR-AURKA FHA(38-105) FHA(38-105) - Pkinase
CHFR CHFR-PLK1 FHA(38-105) FHA(38-105) - Pkinase
CHFR CHFR-UBE2D1 zf-RING_2(303-343) zf-RING_2(303-343) - UQ_con
CHFR CHFR-UBE2D2 zf-RING_2(303-343) zf-RING_2(303-343) - UQ_con
CHFR CHFR-UBC zf-RING_2(303-343) zf-RING_2(303-343) - ubiquitin
CHFR CHFR-HLTF zf-RING_2(303-343) zf-RING_2(303-343) - zf-RING_2

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
Sample ID Disease Type Gene Name 1 Gene Name 2 Transcript Name dMDT
429f0e9d-c160-4b36-a31b-dab1097c6129 Bladder.Bladder-TCC CHFR AURKA CHFR-006 ENST00000537522
429f0e9d-c160-4b36-a31b-dab1097c6129 Bladder.Bladder-TCC CHFR PLK1 CHFR-006 ENST00000537522
429f0e9d-c160-4b36-a31b-dab1097c6129 Bladder.Bladder-TCC CHFR UBE2D1 CHFR-006 ENST00000537522
429f0e9d-c160-4b36-a31b-dab1097c6129 Bladder.Bladder-TCC CHFR UBE2D2 CHFR-006 ENST00000537522
429f0e9d-c160-4b36-a31b-dab1097c6129 Bladder.Bladder-TCC CHFR UBC CHFR-006 ENST00000537522
429f0e9d-c160-4b36-a31b-dab1097c6129 Bladder.Bladder-TCC CHFR HLTF CHFR-006 ENST00000537522
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA CHFR AURKA CHFR-006 ENST00000537522
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA CHFR PLK1 CHFR-006 ENST00000537522
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA CHFR UBE2D1 CHFR-006 ENST00000537522
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA CHFR UBE2D2 CHFR-006 ENST00000537522
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA CHFR UBC CHFR-006 ENST00000537522
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA CHFR HLTF CHFR-006 ENST00000537522
Interaction losses with Clinvar proteins
Gene Name
AURKA