dMDT Interaction Network
Protein interaction losses due to MDT switch
| Gene Name | Interaction Lost | Lost Domain (Region) | Lost Domain - Domain Interaction |
|---|---|---|---|
| CLDN15 | CLDN15-CLDN18 | PMP22_Claudin(8-177) | PMP22_Claudin(8-177) - PMP22_Claudin |
| CLDN15 | CLDN15-CLDN17 | PMP22_Claudin(8-177) | PMP22_Claudin(8-177) - PMP22_Claudin |
| CLDN15 | CLDN15-CLDN22 | PMP22_Claudin(8-177) | PMP22_Claudin(8-177) - PMP22_Claudin |
| CLDN15 | CLDN15-CLDN14 | PMP22_Claudin(8-177) | PMP22_Claudin(8-177) - PMP22_Claudin |
| CLDN15 | CLDN15-CLDN20 | PMP22_Claudin(8-177) | PMP22_Claudin(8-177) - PMP22_Claudin |
| CLDN15 | CLDN15-CLDN9 | PMP22_Claudin(8-177) | PMP22_Claudin(8-177) - PMP22_Claudin |
| CLDN15 | CLDN15-CLDN23 | PMP22_Claudin(8-177) | PMP22_Claudin(8-177) - PMP22_Claudin |
Network Density Score: %
The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
| Sample ID | Disease Type | Gene Name 1 | Gene Name 2 | Transcript Name | dMDT |
|---|---|---|---|---|---|
| 70c76dd2-e52f-4caa-9e73-0c730f8e408a | Blood.Lymph-CLL | CLDN15 | CLDN18 | CLDN15-005 | ENST00000433833 |
| 70c76dd2-e52f-4caa-9e73-0c730f8e408a | Blood.Lymph-CLL | CLDN15 | CLDN17 | CLDN15-005 | ENST00000433833 |
| 70c76dd2-e52f-4caa-9e73-0c730f8e408a | Blood.Lymph-CLL | CLDN15 | CLDN22 | CLDN15-005 | ENST00000433833 |
| 70c76dd2-e52f-4caa-9e73-0c730f8e408a | Blood.Lymph-CLL | CLDN15 | CLDN14 | CLDN15-005 | ENST00000433833 |
| 70c76dd2-e52f-4caa-9e73-0c730f8e408a | Blood.Lymph-CLL | CLDN15 | CLDN20 | CLDN15-005 | ENST00000433833 |
| 70c76dd2-e52f-4caa-9e73-0c730f8e408a | Blood.Lymph-CLL | CLDN15 | CLDN9 | CLDN15-005 | ENST00000433833 |
| 70c76dd2-e52f-4caa-9e73-0c730f8e408a | Blood.Lymph-CLL | CLDN15 | CLDN23 | CLDN15-005 | ENST00000433833 |