CanIsoNet

Gene Name:

Transcript ID:
Transcript Name:
dMDT Interaction Network

Protein interaction losses due to MDT switch
*only proteins having domain-domain interaction information are taken into consideration
Number of Total Interaction:
Number of Lost Interaction:
Gene Name Interaction Lost Lost Domain (Region) Lost Domain - Domain Interaction
CNOT1 CNOT1-CNOT3 Not1(1996-2359) Not1(1996-2359) - NOT2_3_5
CNOT1 CNOT1-CNOT2 Not1(1996-2359) Not1(1996-2359) - NOT2_3_5
CNOT1 CNOT1-RQCD1 DUF3819(1386-1535) DUF3819(1386-1535) - Rcd1

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
Sample ID Disease Type Gene Name 1 Gene Name 2 Transcript Name dMDT
82bb01e9-a659-417b-b9e8-831a76277a21 Colon.ColoRect-AdenoCA CNOT1 CNOT3 CNOT1-017 ENST00000567133
82bb01e9-a659-417b-b9e8-831a76277a21 Colon.ColoRect-AdenoCA CNOT1 CNOT2 CNOT1-017 ENST00000567133
82bb01e9-a659-417b-b9e8-831a76277a21 Colon.ColoRect-AdenoCA CNOT1 RQCD1 CNOT1-017 ENST00000567133
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA CNOT1 CNOT3 CNOT1-017 ENST00000567133
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA CNOT1 CNOT2 CNOT1-017 ENST00000567133
932c2e20-510c-4aed-879e-b69d90710b64 Colon.ColoRect-AdenoCA CNOT1 RQCD1 CNOT1-017 ENST00000567133
Interaction losses with Clinvar proteins
Gene Name
CNOT1
CNOT2
CNOT3