CanIsoNet

Gene Name:

Transcript ID:
Transcript Name:
dMDT Interaction Network

Protein interaction losses due to MDT switch
*only proteins having domain-domain interaction information are taken into consideration
Number of Total Interaction:
Number of Lost Interaction:
Gene Name Interaction Lost Lost Domain (Region) Lost Domain - Domain Interaction
CNOT2 CNOT2-CNOT1 NOT2_3_5(395-522) NOT2_3_5(395-522) - Not1
CNOT2 CNOT2-CNOT3 NOT2_3_5(395-522) NOT2_3_5(395-522) - NOT2_3_5

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
Sample ID Disease Type Gene Name 1 Gene Name 2 Transcript Name dMDT
24664b94-f5b5-4a99-a09b-66e23edf5916 Breast.Breast-AdenoCA CNOT2 CNOT1 CNOT2-013 ENST00000551132
24664b94-f5b5-4a99-a09b-66e23edf5916 Breast.Breast-AdenoCA CNOT2 CNOT3 CNOT2-013 ENST00000551132
6ccc37a2-f073-4050-bfcd-de106d86236b Lung.Lung-SCC CNOT2 CNOT1 CNOT2-013 ENST00000551132
6ccc37a2-f073-4050-bfcd-de106d86236b Lung.Lung-SCC CNOT2 CNOT3 CNOT2-013 ENST00000551132
00055bad-54b7-4898-a9ae-3dd8036e62d3 Uterus.Uterus-AdenoCA CNOT2 CNOT1 CNOT2-013 ENST00000551132
00055bad-54b7-4898-a9ae-3dd8036e62d3 Uterus.Uterus-AdenoCA CNOT2 CNOT3 CNOT2-013 ENST00000551132
Interaction losses with Clinvar proteins
Gene Name
CNOT1
CNOT2
CNOT3