CanIsoNet

Gene Name:

Transcript ID:
Transcript Name:
dMDT Interaction Network

Protein interaction losses due to MDT switch
*only proteins having domain-domain interaction information are taken into consideration
Number of Total Interaction:
Number of Lost Interaction:
Gene Name Interaction Lost Lost Domain (Region) Lost Domain - Domain Interaction
CUL2 CUL2-UBE2D1 Cullin_Nedd8(685-749) Cullin_Nedd8(685-749) - UQ_con
CUL2 CUL2-UBE2D2 Cullin_Nedd8(685-749) Cullin_Nedd8(685-749) - UQ_con
CUL2 CUL2-NEDD8 Cullin_Nedd8(685-749) Cullin_Nedd8(685-749) - ubiquitin
CUL2 CUL2-TCEB2 Cullin_Nedd8(685-749) Cullin_Nedd8(685-749) - ubiquitin
CUL2 CUL2-RPS27A Cullin_Nedd8(685-749) Cullin_Nedd8(685-749) - ubiquitin
CUL2 CUL2-UBB Cullin_Nedd8(685-749) Cullin_Nedd8(685-749) - ubiquitin
CUL2 CUL2-UBC Cullin_Nedd8(685-749) Cullin_Nedd8(685-749) - ubiquitin
CUL2 CUL2-UBA52 Cullin_Nedd8(685-749) Cullin_Nedd8(685-749) - ubiquitin
CUL2 CUL2-DCUN1D1 Cullin_Nedd8(685-749) Cullin_Nedd8(685-749) - Cullin_binding

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
Sample ID Disease Type Gene Name 1 Gene Name 2 Transcript Name dMDT
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA CUL2 UBE2D1 CUL2-005 ENST00000374746
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA CUL2 UBE2D2 CUL2-005 ENST00000374746
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA CUL2 NEDD8 CUL2-005 ENST00000374746
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA CUL2 TCEB2 CUL2-005 ENST00000374746
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA CUL2 RPS27A CUL2-005 ENST00000374746
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA CUL2 UBB CUL2-005 ENST00000374746
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA CUL2 UBC CUL2-005 ENST00000374746
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA CUL2 UBA52 CUL2-005 ENST00000374746
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA CUL2 DCUN1D1 CUL2-005 ENST00000374746
Interaction losses with Clinvar proteins
Gene Name