CanIsoNet

Gene Name:

Transcript ID:
Transcript Name:
dMDT Interaction Network

Protein interaction losses due to MDT switch
*only proteins having domain-domain interaction information are taken into consideration
Number of Total Interaction:
Number of Lost Interaction:
Gene Name Interaction Lost Lost Domain (Region) Lost Domain - Domain Interaction
DGKA DGKA-PLCG1 C1_1(270-321) C1_1(270-321) - SH2
DGKA DGKA-PLCG2 C1_1(270-321) C1_1(270-321) - SH2
DGKA DGKA-PLCB2 C1_1(270-321) C1_1(270-321) - C2
DGKA DGKA-PLCE1 C1_1(270-321) C1_1(270-321) - C2
DGKA DGKA-PLCZ1 C1_1(270-321) C1_1(270-321) - C2
DGKA DGKA-PLCB3 C1_1(270-321) C1_1(270-321) - C2
DGKA DGKA-PLCB1 C1_1(270-321) C1_1(270-321) - C2
DGKA DGKA-PLCD4 C1_1(270-321) C1_1(270-321) - C2
DGKA DGKA-PLCD1 C1_1(270-321) C1_1(270-321) - C2
DGKA DGKA-PLD1 C1_1(270-321) C1_1(270-321) - PH

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
Sample ID Disease Type Gene Name 1 Gene Name 2 Transcript Name dMDT
f2b0f1d8-8714-40c8-bccc-1df3bf3e19f1 Pancreas.Panc-AdenoCA DGKA PLCG1 DGKA-016 ENST00000547015
f2b0f1d8-8714-40c8-bccc-1df3bf3e19f1 Pancreas.Panc-AdenoCA DGKA PLCG2 DGKA-016 ENST00000547015
f2b0f1d8-8714-40c8-bccc-1df3bf3e19f1 Pancreas.Panc-AdenoCA DGKA PLCB2 DGKA-016 ENST00000547015
f2b0f1d8-8714-40c8-bccc-1df3bf3e19f1 Pancreas.Panc-AdenoCA DGKA PLCE1 DGKA-016 ENST00000547015
f2b0f1d8-8714-40c8-bccc-1df3bf3e19f1 Pancreas.Panc-AdenoCA DGKA PLCZ1 DGKA-016 ENST00000547015
f2b0f1d8-8714-40c8-bccc-1df3bf3e19f1 Pancreas.Panc-AdenoCA DGKA PLCB3 DGKA-016 ENST00000547015
f2b0f1d8-8714-40c8-bccc-1df3bf3e19f1 Pancreas.Panc-AdenoCA DGKA PLCB1 DGKA-016 ENST00000547015
f2b0f1d8-8714-40c8-bccc-1df3bf3e19f1 Pancreas.Panc-AdenoCA DGKA PLCD4 DGKA-016 ENST00000547015
f2b0f1d8-8714-40c8-bccc-1df3bf3e19f1 Pancreas.Panc-AdenoCA DGKA PLCD1 DGKA-016 ENST00000547015
f2b0f1d8-8714-40c8-bccc-1df3bf3e19f1 Pancreas.Panc-AdenoCA DGKA PLD1 DGKA-016 ENST00000547015
95698d6f-5687-4261-a6f4-30a349f74baf Stomach.Stomach-AdenoCA DGKA PLCG1 DGKA-016 ENST00000547015
95698d6f-5687-4261-a6f4-30a349f74baf Stomach.Stomach-AdenoCA DGKA PLCG2 DGKA-016 ENST00000547015
95698d6f-5687-4261-a6f4-30a349f74baf Stomach.Stomach-AdenoCA DGKA PLCB2 DGKA-016 ENST00000547015
95698d6f-5687-4261-a6f4-30a349f74baf Stomach.Stomach-AdenoCA DGKA PLCE1 DGKA-016 ENST00000547015
95698d6f-5687-4261-a6f4-30a349f74baf Stomach.Stomach-AdenoCA DGKA PLCZ1 DGKA-016 ENST00000547015
95698d6f-5687-4261-a6f4-30a349f74baf Stomach.Stomach-AdenoCA DGKA PLCB3 DGKA-016 ENST00000547015
95698d6f-5687-4261-a6f4-30a349f74baf Stomach.Stomach-AdenoCA DGKA PLCB1 DGKA-016 ENST00000547015
95698d6f-5687-4261-a6f4-30a349f74baf Stomach.Stomach-AdenoCA DGKA PLCD4 DGKA-016 ENST00000547015
95698d6f-5687-4261-a6f4-30a349f74baf Stomach.Stomach-AdenoCA DGKA PLCD1 DGKA-016 ENST00000547015
95698d6f-5687-4261-a6f4-30a349f74baf Stomach.Stomach-AdenoCA DGKA PLD1 DGKA-016 ENST00000547015
00055bad-54b7-4898-a9ae-3dd8036e62d3 Uterus.Uterus-AdenoCA DGKA PLCG1 DGKA-016 ENST00000547015
00055bad-54b7-4898-a9ae-3dd8036e62d3 Uterus.Uterus-AdenoCA DGKA PLCG2 DGKA-016 ENST00000547015
00055bad-54b7-4898-a9ae-3dd8036e62d3 Uterus.Uterus-AdenoCA DGKA PLCB2 DGKA-016 ENST00000547015
00055bad-54b7-4898-a9ae-3dd8036e62d3 Uterus.Uterus-AdenoCA DGKA PLCE1 DGKA-016 ENST00000547015
00055bad-54b7-4898-a9ae-3dd8036e62d3 Uterus.Uterus-AdenoCA DGKA PLCZ1 DGKA-016 ENST00000547015
00055bad-54b7-4898-a9ae-3dd8036e62d3 Uterus.Uterus-AdenoCA DGKA PLCB3 DGKA-016 ENST00000547015
00055bad-54b7-4898-a9ae-3dd8036e62d3 Uterus.Uterus-AdenoCA DGKA PLCB1 DGKA-016 ENST00000547015
00055bad-54b7-4898-a9ae-3dd8036e62d3 Uterus.Uterus-AdenoCA DGKA PLCD4 DGKA-016 ENST00000547015
00055bad-54b7-4898-a9ae-3dd8036e62d3 Uterus.Uterus-AdenoCA DGKA PLCD1 DGKA-016 ENST00000547015
00055bad-54b7-4898-a9ae-3dd8036e62d3 Uterus.Uterus-AdenoCA DGKA PLD1 DGKA-016 ENST00000547015
Interaction losses with Clinvar proteins
Gene Name
PLCB1
PLCB3
PLCD1
PLCE1
PLCG2
PLCZ1
PLD1