CanIsoNet

Gene Name:

Transcript ID:
Transcript Name:
dMDT Interaction Network

Protein interaction losses due to MDT switch
*only proteins having domain-domain interaction information are taken into consideration
Number of Total Interaction:
Number of Lost Interaction:
Gene Name Interaction Lost Lost Domain (Region) Lost Domain - Domain Interaction
DYNC1H1 DYNC1H1-DNAH3 Dynein_heavy(3920-4644) Dynein_heavy(3920-4644) - Dynein_heavy
DYNC1H1 DYNC1H1-DNAH7 Dynein_heavy(3920-4644) Dynein_heavy(3920-4644) - Dynein_heavy
DYNC1H1 DYNC1H1-DNAH8 Dynein_heavy(3920-4644) Dynein_heavy(3920-4644) - Dynein_heavy
DYNC1H1 DYNC1H1-DNAH2 Dynein_heavy(3920-4644) Dynein_heavy(3920-4644) - Dynein_heavy
DYNC1H1 DYNC1H1-DNAH17 Dynein_heavy(3920-4644) Dynein_heavy(3920-4644) - Dynein_heavy
DYNC1H1 DYNC1H1-DYNC2H1 Dynein_heavy(3920-4644) Dynein_heavy(3920-4644) - Dynein_heavy
DYNC1H1 DYNC1H1-DNAH1 Dynein_heavy(3920-4644) Dynein_heavy(3920-4644) - Dynein_heavy
DYNC1H1 DYNC1H1-ACTR1B DHC_N1(238-834) DHC_N1(238-834) - Actin
DYNC1H1 DYNC1H1-ACTR1A DHC_N1(238-834) DHC_N1(238-834) - Actin
DYNC1H1 DYNC1H1-DYNC1I1 DHC_N1(238-834) DHC_N1(238-834) - WD40
DYNC1H1 DYNC1H1-DYNC1I2 DHC_N1(238-834) DHC_N1(238-834) - WD40
DYNC1H1 DYNC1H1-PAFAH1B1 DHC_N1(238-834) DHC_N1(238-834) - WD40
DYNC1H1 DYNC1H1-NEDD1 DHC_N1(238-834) DHC_N1(238-834) - WD40
DYNC1H1 DYNC1H1-DYNC1LI2 DHC_N1(238-834) DHC_N1(238-834) - DLIC
DYNC1H1 DYNC1H1-DYNC2LI1 DHC_N1(238-834) DHC_N1(238-834) - DLIC
DYNC1H1 DYNC1H1-DYNC1LI1 DHC_N1(238-834) DHC_N1(238-834) - DLIC
DYNC1H1 DYNC1H1-TUBB1 MT(3201-3530) MT(3201-3530) - Tubulin
DYNC1H1 DYNC1H1-TUBA4A MT(3201-3530) MT(3201-3530) - Tubulin
DYNC1H1 DYNC1H1-TUBG2 MT(3201-3530) MT(3201-3530) - Tubulin
DYNC1H1 DYNC1H1-TUBG1 MT(3201-3530) MT(3201-3530) - Tubulin
DYNC1H1 DYNC1H1-TUBB2B MT(3201-3530) MT(3201-3530) - Tubulin
DYNC1H1 DYNC1H1-TUBB4A MT(3201-3530) MT(3201-3530) - Tubulin
DYNC1H1 DYNC1H1-TUBA1A MT(3201-3530) MT(3201-3530) - Tubulin
DYNC1H1 DYNC1H1-TUBA1C MT(3201-3530) MT(3201-3530) - Tubulin
DYNC1H1 DYNC1H1-TUBA3E MT(3201-3530) MT(3201-3530) - Tubulin
DYNC1H1 DYNC1H1-TUBB6 MT(3201-3530) MT(3201-3530) - Tubulin
DYNC1H1 DYNC1H1-TUBA1B MT(3201-3530) MT(3201-3530) - Tubulin
DYNC1H1 DYNC1H1-TUBB4B MT(3201-3530) MT(3201-3530) - Tubulin
DYNC1H1 DYNC1H1-TUBB2A MT(3201-3530) MT(3201-3530) - Tubulin
DYNC1H1 DYNC1H1-TUBA3C MT(3201-3530) MT(3201-3530) - Tubulin
DYNC1H1 DYNC1H1-TUBB3 MT(3201-3530) MT(3201-3530) - Tubulin

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
Sample ID Disease Type Gene Name 1 Gene Name 2 Transcript Name dMDT
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA DYNC1H1 DNAH3 DYNC1H1-008 ENST00000553423
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA DYNC1H1 DNAH7 DYNC1H1-008 ENST00000553423
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA DYNC1H1 DNAH8 DYNC1H1-008 ENST00000553423
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA DYNC1H1 DNAH2 DYNC1H1-008 ENST00000553423
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA DYNC1H1 DNAH17 DYNC1H1-008 ENST00000553423
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA DYNC1H1 DYNC2H1 DYNC1H1-008 ENST00000553423
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA DYNC1H1 DNAH1 DYNC1H1-008 ENST00000553423
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA DYNC1H1 ACTR1B DYNC1H1-008 ENST00000553423
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA DYNC1H1 ACTR1A DYNC1H1-008 ENST00000553423
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA DYNC1H1 DYNC1I1 DYNC1H1-008 ENST00000553423
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA DYNC1H1 DYNC1I2 DYNC1H1-008 ENST00000553423
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA DYNC1H1 PAFAH1B1 DYNC1H1-008 ENST00000553423
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA DYNC1H1 NEDD1 DYNC1H1-008 ENST00000553423
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA DYNC1H1 DYNC1LI2 DYNC1H1-008 ENST00000553423
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA DYNC1H1 DYNC2LI1 DYNC1H1-008 ENST00000553423
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA DYNC1H1 DYNC1LI1 DYNC1H1-008 ENST00000553423
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA DYNC1H1 TUBB1 DYNC1H1-008 ENST00000553423
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA DYNC1H1 TUBA4A DYNC1H1-008 ENST00000553423
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA DYNC1H1 TUBG2 DYNC1H1-008 ENST00000553423
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA DYNC1H1 TUBG1 DYNC1H1-008 ENST00000553423
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA DYNC1H1 TUBB2B DYNC1H1-008 ENST00000553423
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA DYNC1H1 TUBB4A DYNC1H1-008 ENST00000553423
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA DYNC1H1 TUBA1A DYNC1H1-008 ENST00000553423
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA DYNC1H1 TUBA1C DYNC1H1-008 ENST00000553423
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA DYNC1H1 TUBA3E DYNC1H1-008 ENST00000553423
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA DYNC1H1 TUBB6 DYNC1H1-008 ENST00000553423
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA DYNC1H1 TUBA1B DYNC1H1-008 ENST00000553423
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA DYNC1H1 TUBB4B DYNC1H1-008 ENST00000553423
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA DYNC1H1 TUBB2A DYNC1H1-008 ENST00000553423
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA DYNC1H1 TUBA3C DYNC1H1-008 ENST00000553423
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA DYNC1H1 TUBB3 DYNC1H1-008 ENST00000553423
Interaction losses with Clinvar proteins
Gene Name
DNAH1
DNAH17
DNAH2
DNAH8
DYNC1H1
DYNC1I2
DYNC2H1
DYNC2LI1
PAFAH1B1
TUBA1A
TUBA4A
TUBB1
TUBB2A
TUBB2B
TUBB3
TUBB4A
TUBB4B
TUBB6
TUBG1