dMDT Interaction Network
Protein interaction losses due to MDT switch
| Gene Name | Interaction Lost | Lost Domain (Region) | Lost Domain - Domain Interaction |
|---|---|---|---|
| DYNC1I2 | DYNC1I2-DYNLL1 | Dynein_IC2(132-164) | Dynein_IC2(132-164) - Dynein_light |
| DYNC1I2 | DYNC1I2-DYNLT3 | Dynein_IC2(132-164) | Dynein_IC2(132-164) - Tctex-1 |
Network Density Score: %
The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
| Sample ID | Disease Type | Gene Name 1 | Gene Name 2 | Transcript Name | dMDT |
|---|---|---|---|---|---|
| SRR19243445 | Alzheimer's disease | DYNC1I2 | DYNLL1 | DYNC1I2-006 | ENST00000409197 |
| SRR19243445 | Alzheimer's disease | DYNC1I2 | DYNLT3 | DYNC1I2-006 | ENST00000409197 |
| SRR19243468 | Alzheimer's disease | DYNC1I2 | DYNLL1 | DYNC1I2-006 | ENST00000409197 |
| SRR19243468 | Alzheimer's disease | DYNC1I2 | DYNLT3 | DYNC1I2-006 | ENST00000409197 |
| SRR19243474 | Alzheimer's disease | DYNC1I2 | DYNLL1 | DYNC1I2-006 | ENST00000409197 |
| SRR19243474 | Alzheimer's disease | DYNC1I2 | DYNLT3 | DYNC1I2-006 | ENST00000409197 |
Interaction losses with Clinvar proteins
| Gene Name |
|---|
| DYNC1I2 |