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Specific dMDT
Disease-type-specific MDTs
Lost Domain in dMDT
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Gene Name:
Transcript ID:
Transcript Name:
dMDT Interaction Network
Protein interaction losses due to MDT switch
*only proteins having domain-domain interaction information are taken into consideration
Number of Total Interaction:
Number of Lost Interaction:
Gene Name
Interaction Lost
Lost Domain (Region)
Lost Domain - Domain Interaction
DYRK1B
DYRK1B
-RHOA
Pkinase
(111-431)
Pkinase
(111-431) -
Ras
Network Density Score:
%
The local network of this protein has more interaction than
% of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
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Sample ID
Disease Type
Gene Name 1
Gene Name 2
Transcript Name
dMDT
28904a18-b1fc-4d2f-8cd5-3f7ff759dac1
Colon.ColoRect-AdenoCA
DYRK1B
RHOA
DYRK1B-007
ENST00000430012
2ee1e0d0-79f9-4e02-be27-773ee4b88320
Colon.ColoRect-AdenoCA
DYRK1B
RHOA
DYRK1B-007
ENST00000430012
4c006fb2-f1e6-4d7d-b6f5-bf28b46035c0
Colon.ColoRect-AdenoCA
DYRK1B
RHOA
DYRK1B-007
ENST00000430012
82a1c742-2d97-4c7a-bf1d-ca0233c60b6c
Colon.ColoRect-AdenoCA
DYRK1B
RHOA
DYRK1B-007
ENST00000430012
d660ee4f-58f3-4fd9-997a-6a2d0eefa66f
Colon.ColoRect-AdenoCA
DYRK1B
RHOA
DYRK1B-007
ENST00000430012
06dbb69c-390b-4174-859b-c1e20380b483
Stomach.Stomach-AdenoCA
DYRK1B
RHOA
DYRK1B-007
ENST00000430012
Interaction losses with Clinvar proteins
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Gene Name
DYRK1B
RHOA