dMDT Interaction Network
Protein interaction losses due to MDT switch
| Gene Name | Interaction Lost | Lost Domain (Region) | Lost Domain - Domain Interaction |
|---|---|---|---|
| FAS | FAS-RIPK1 | Death(238-313) | Death(238-313) - Death |
| FAS | FAS-FADD | Death(238-313) | Death(238-313) - Death |
| FAS | FAS-TRADD | Death(238-313) | Death(238-313) - Death |
| FAS | FAS-RIPK2 | Death(238-313) | Death(238-313) - CARD |
| FAS | FAS-BIRC2 | Death(238-313) | Death(238-313) - CARD |
| FAS | FAS-BIRC3 | Death(238-313) | Death(238-313) - CARD |
Network Density Score: %
The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
| Sample ID | Disease Type | Gene Name 1 | Gene Name 2 | Transcript Name | dMDT |
|---|---|---|---|---|---|
| 310820cc-fc05-45c6-8f04-a44db0828686 | Colon.ColoRect-AdenoCA | FAS | RIPK1 | FAS-016 | ENST00000352159 |
| 310820cc-fc05-45c6-8f04-a44db0828686 | Colon.ColoRect-AdenoCA | FAS | FADD | FAS-016 | ENST00000352159 |
| 310820cc-fc05-45c6-8f04-a44db0828686 | Colon.ColoRect-AdenoCA | FAS | TRADD | FAS-016 | ENST00000352159 |
| 310820cc-fc05-45c6-8f04-a44db0828686 | Colon.ColoRect-AdenoCA | FAS | RIPK2 | FAS-016 | ENST00000352159 |
| 310820cc-fc05-45c6-8f04-a44db0828686 | Colon.ColoRect-AdenoCA | FAS | BIRC2 | FAS-016 | ENST00000352159 |
| 310820cc-fc05-45c6-8f04-a44db0828686 | Colon.ColoRect-AdenoCA | FAS | BIRC3 | FAS-016 | ENST00000352159 |