dMDT Interaction Network
Protein interaction losses due to MDT switch
| Gene Name | Interaction Lost | Lost Domain (Region) | Lost Domain - Domain Interaction |
|---|---|---|---|
| GAB1 | GAB1-CSK | PH(6-115) | PH(6-115) - SH3_1 |
| GAB1 | GAB1-NCK2 | PH(6-115) | PH(6-115) - SH3_1 |
| GAB1 | GAB1-PLCG1 | PH(6-115) | PH(6-115) - SH3_1 |
| GAB1 | GAB1-GRAP | PH(6-115) | PH(6-115) - SH3_1 |
| GAB1 | GAB1-NCK1 | PH(6-115) | PH(6-115) - SH3_1 |
| GAB1 | GAB1-CRK | PH(6-115) | PH(6-115) - SH3_1 |
| GAB1 | GAB1-GRB2 | PH(6-115) | PH(6-115) - SH3_1 |
| GAB1 | GAB1-GRAP2 | PH(6-115) | PH(6-115) - SH3_1 |
| GAB1 | GAB1-CRKL | PH(6-115) | PH(6-115) - SH3_1 |
| GAB1 | GAB1-SRC | PH(6-115) | PH(6-115) - SH3_1 |
| GAB1 | GAB1-HCK | PH(6-115) | PH(6-115) - SH3_1 |
| GAB1 | GAB1-MAPK1 | PH(6-115) | PH(6-115) - Pkinase |
| GAB1 | GAB1-MAPK3 | PH(6-115) | PH(6-115) - Pkinase |
| GAB1 | GAB1-AKT1 | PH(6-115) | PH(6-115) - Pkinase |
| GAB1 | GAB1-MAP2K1 | PH(6-115) | PH(6-115) - Pkinase |
| GAB1 | GAB1-PRKACA | PH(6-115) | PH(6-115) - Pkinase |
| GAB1 | GAB1-PAK4 | PH(6-115) | PH(6-115) - Pkinase |
| GAB1 | GAB1-MAPK8 | PH(6-115) | PH(6-115) - Pkinase |
| GAB1 | GAB1-ROCK1 | PH(6-115) | PH(6-115) - Pkinase |
| GAB1 | GAB1-HRAS | PH(6-115) | PH(6-115) - Ras |
| GAB1 | GAB1-RAC1 | PH(6-115) | PH(6-115) - Ras |
| GAB1 | GAB1-GAB2 | PH(6-115) | PH(6-115) - PH |
| GAB1 | GAB1-SOS1 | PH(6-115) | PH(6-115) - PH |
| GAB1 | GAB1-ARPC1B | PH(6-115) | PH(6-115) - WD40 |
| GAB1 | GAB1-PDGFRB | PH(6-115) | PH(6-115) - Pkinase_Tyr |
| GAB1 | GAB1-KDR | PH(6-115) | PH(6-115) - Pkinase_Tyr |
| GAB1 | GAB1-EGFR | PH(6-115) | PH(6-115) - Pkinase_Tyr |
| GAB1 | GAB1-KIT | PH(6-115) | PH(6-115) - Pkinase_Tyr |
| GAB1 | GAB1-MST1R | PH(6-115) | PH(6-115) - Pkinase_Tyr |
| GAB1 | GAB1-MET | PH(6-115) | PH(6-115) - Pkinase_Tyr |
| GAB1 | GAB1-JAK1 | PH(6-115) | PH(6-115) - Pkinase_Tyr |
| GAB1 | GAB1-RET | PH(6-115) | PH(6-115) - Pkinase_Tyr |
| GAB1 | GAB1-JAK2 | PH(6-115) | PH(6-115) - Pkinase_Tyr |
| GAB1 | None | None | None |
Network Density Score: %
The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch