CanIsoNet

Gene Name:

Transcript ID:
Transcript Name:
dMDT Interaction Network

Protein interaction losses due to MDT switch
*only proteins having domain-domain interaction information are taken into consideration
Number of Total Interaction:
Number of Lost Interaction:
Gene Name Interaction Lost Lost Domain (Region) Lost Domain - Domain Interaction
GLI3 GLI3-GLI1 zf-C2H2(607-632) zf-C2H2(607-632) - zf-C2H2
GLI3 GLI3-GLI2 zf-C2H2(607-632) zf-C2H2(607-632) - zf-C2H2
GLI3 GLI3-ZIC2 zf-C2H2(607-632) zf-C2H2(607-632) - zf-C2H2

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
Sample ID Disease Type Gene Name 1 Gene Name 2 Transcript Name dMDT
a344de7b-5980-4612-9d58-1c8058a2bfd9 Brain.CNS-GBM GLI3 GLI1 GLI3-005 ENST00000448703
a344de7b-5980-4612-9d58-1c8058a2bfd9 Brain.CNS-GBM GLI3 GLI2 GLI3-005 ENST00000448703
a344de7b-5980-4612-9d58-1c8058a2bfd9 Brain.CNS-GBM GLI3 ZIC2 GLI3-005 ENST00000448703
adfbf8b6-405d-4887-b363-d130e20b70ef Lung.Lung-SCC GLI3 GLI1 GLI3-005 ENST00000448703
adfbf8b6-405d-4887-b363-d130e20b70ef Lung.Lung-SCC GLI3 GLI2 GLI3-005 ENST00000448703
adfbf8b6-405d-4887-b363-d130e20b70ef Lung.Lung-SCC GLI3 ZIC2 GLI3-005 ENST00000448703
Interaction losses with Clinvar proteins
Gene Name
GLI1
GLI2
GLI3
ZIC2