CanIsoNet

Gene Name:

Transcript ID:
Transcript Name:
dMDT Interaction Network

Protein interaction losses due to MDT switch
*only proteins having domain-domain interaction information are taken into consideration
Number of Total Interaction:
Number of Lost Interaction:
Gene Name Interaction Lost Lost Domain (Region) Lost Domain - Domain Interaction
HADHA HADHA-ACAT1 ECH(42-309) ECH(42-309) - Thiolase_N
HADHA HADHA-ACAA2 ECH(42-309) ECH(42-309) - Thiolase_N
HADHA HADHA-HADHB ECH(42-309) ECH(42-309) - Thiolase_N
HADHA HADHA-ACAA1 ECH(42-309) ECH(42-309) - Thiolase_N
HADHA HADHA-ACAT2 ECH(42-309) ECH(42-309) - Thiolase_N
HADHA HADHA-EHHADH ECH(42-309) ECH(42-309) - ECH
HADHA HADHA-ECI1 ECH(42-309) ECH(42-309) - ECH
HADHA HADHA-ECHS1 ECH(42-309) ECH(42-309) - ECH

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
Sample ID Disease Type Gene Name 1 Gene Name 2 Transcript Name dMDT
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA HADHA ACAT1 HADHA-004 ENST00000492433
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA HADHA ACAA2 HADHA-004 ENST00000492433
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA HADHA HADHB HADHA-004 ENST00000492433
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA HADHA ACAA1 HADHA-004 ENST00000492433
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA HADHA ACAT2 HADHA-004 ENST00000492433
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA HADHA EHHADH HADHA-004 ENST00000492433
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA HADHA ECI1 HADHA-004 ENST00000492433
37725090-996e-4ab2-bbf6-dc3d2970e387 Esophagus.Eso-AdenoCA HADHA ECHS1 HADHA-004 ENST00000492433
Interaction losses with Clinvar proteins
Gene Name
ACAT1
ACAT2
ECHS1
EHHADH
HADHA
HADHB