dMDT Interaction Network
Protein interaction losses due to MDT switch
| Gene Name | Interaction Lost | Lost Domain (Region) | Lost Domain - Domain Interaction |
|---|---|---|---|
| IL12RB2 | IL12RB2-IL5 | IL6Ra-bind(127-218) | IL6Ra-bind(127-218) - IL5 |
| IL12RB2 | IL12RB2-STAT3 | fn3(523-607) | fn3(523-607) - SH2 |
| IL12RB2 | IL12RB2-STAT6 | fn3(523-607) | fn3(523-607) - SH2 |
| IL12RB2 | IL12RB2-SOCS1 | fn3(523-607) | fn3(523-607) - SH2 |
| IL12RB2 | IL12RB2-SOCS3 | fn3(523-607) | fn3(523-607) - SH2 |
| IL12RB2 | IL12RB2-LCK | fn3(523-607) | fn3(523-607) - SH2 |
| IL12RB2 | IL12RB2-STAT5A | fn3(523-607) | fn3(523-607) - SH2 |
| IL12RB2 | IL12RB2-STAT4 | fn3(523-607) | fn3(523-607) - SH2 |
| IL12RB2 | IL12RB2-STAT1 | fn3(523-607) | fn3(523-607) - SH2 |
| IL12RB2 | IL12RB2-JAK2 | fn3(523-607) | fn3(523-607) - SH2 |
| IL12RB2 | IL12RB2-IL4 | fn3(523-607) | fn3(523-607) - IL4 |
| IL12RB2 | IL12RB2-IL12B | fn3(523-607) | fn3(523-607) - IL12p40_C |
| IL12RB2 | IL12RB2-IL5 | IL6Ra-bind(127-218) | IL6Ra-bind(127-218) - IL5 |
Network Density Score: %
The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch