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Specific dMDT
Disease-type-specific MDTs
Lost Domain in dMDT
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Gene Name:
Transcript ID:
Transcript Name:
dMDT Interaction Network
Protein interaction losses due to MDT switch
*only proteins having domain-domain interaction information are taken into consideration
Number of Total Interaction:
Number of Lost Interaction:
Gene Name
Interaction Lost
Lost Domain (Region)
Lost Domain - Domain Interaction
KALRN
None
None
None
Network Density Score:
%
The local network of this protein has more interaction than
% of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
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Sample ID
Disease Type
Gene Name 1
Gene Name 2
Transcript Name
dMDT
312ea080-3831-453d-aa8c-e466192c8309
Bladder.Bladder-TCC
KALRN
None
KALRN-009
ENST00000439170
56e6f602-0afb-434e-b28e-665d923ad781
Liver.Liver-HCC
KALRN
None
KALRN-009
ENST00000439170
0e17aa25-2993-4ea1-bbee-d600d8c0bf89
Lung.Lung-SCC
KALRN
None
KALRN-009
ENST00000439170
358984cc-b532-4f00-89f4-dda524469b6d
Ovary.Ovary-AdenoCA
KALRN
None
KALRN-009
ENST00000439170
cf1625b4-f30b-487f-8e2c-2866af730c7f
Ovary.Ovary-AdenoCA
KALRN
None
KALRN-009
ENST00000439170
f05dba68-a8a6-4770-9e4d-62d3a9d70a79
Ovary.Ovary-AdenoCA
KALRN
None
KALRN-009
ENST00000439170
de485b7d-cd88-4889-aff4-e290027f26bb
Uterus.Uterus-AdenoCA
KALRN
None
KALRN-009
ENST00000439170
Interaction losses with Clinvar proteins
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Gene Name
ARHGAP26
ARHGEF1
ARHGEF18
ARHGEF2
BCR
CDC42
CHN1
EPHB2
FGD1
FGD4
GNA11
GNAQ
PLEKHG5
RAC1
RAC2
RAC3
RACGAP1
RHOA
RHOBTB2
RHOH
SOS1
SOS2
SRGAP1
TIAM1