dMDT Interaction Network
Protein interaction losses due to MDT switch
| Gene Name | Interaction Lost | Lost Domain (Region) | Lost Domain - Domain Interaction |
|---|---|---|---|
| KLHL2 | KLHL2-KLHL12 | BTB(50-156) | BTB(50-156) - BTB |
| KLHL2 | KLHL2-CUL3 | BTB(50-156) | BTB(50-156) - Cullin |
Network Density Score: %
The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
| Sample ID | Disease Type | Gene Name 1 | Gene Name 2 | Transcript Name | dMDT |
|---|---|---|---|---|---|
| e62793b0-8fb2-4c91-9f64-c0eae21571a7 | Uterus.Uterus-AdenoCA | KLHL2 | KLHL12 | KLHL2-004 | ENST00000421009 |
| e62793b0-8fb2-4c91-9f64-c0eae21571a7 | Uterus.Uterus-AdenoCA | KLHL2 | CUL3 | KLHL2-004 | ENST00000421009 |
Interaction losses with Clinvar proteins
| Gene Name |
|---|
| CUL3 |