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Specific dMDT
Disease-type-specific MDTs
Lost Domain in dMDT
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Gene Name:
Transcript ID:
Transcript Name:
dMDT Interaction Network
Protein interaction losses due to MDT switch
*only proteins having domain-domain interaction information are taken into consideration
Number of Total Interaction:
Number of Lost Interaction:
Gene Name
Interaction Lost
Lost Domain (Region)
Lost Domain - Domain Interaction
KLHL2
KLHL2
-KLHL12
BTB
(50-156)
BTB
(50-156) -
BTB
KLHL2
KLHL2
-CUL3
BTB
(50-156)
BTB
(50-156) -
Cullin
Network Density Score:
%
The local network of this protein has more interaction than
% of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
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Sample ID
Disease Type
Gene Name 1
Gene Name 2
Transcript Name
dMDT
310820cc-fc05-45c6-8f04-a44db0828686
Colon.ColoRect-AdenoCA
KLHL2
KLHL12
KLHL2-005
ENST00000506761
310820cc-fc05-45c6-8f04-a44db0828686
Colon.ColoRect-AdenoCA
KLHL2
CUL3
KLHL2-005
ENST00000506761
bd33fafa-9922-4efe-9e1d-c8d8f6b8e7cc
Colon.ColoRect-AdenoCA
KLHL2
KLHL12
KLHL2-005
ENST00000506761
bd33fafa-9922-4efe-9e1d-c8d8f6b8e7cc
Colon.ColoRect-AdenoCA
KLHL2
CUL3
KLHL2-005
ENST00000506761
15c0fde7-d2b9-434d-81be-196d49244f8d
Ovary.Ovary-AdenoCA
KLHL2
KLHL12
KLHL2-005
ENST00000506761
15c0fde7-d2b9-434d-81be-196d49244f8d
Ovary.Ovary-AdenoCA
KLHL2
CUL3
KLHL2-005
ENST00000506761
c60df680-5bd6-48cc-a112-985f73d9092c
Uterus.Uterus-AdenoCA
KLHL2
KLHL12
KLHL2-005
ENST00000506761
c60df680-5bd6-48cc-a112-985f73d9092c
Uterus.Uterus-AdenoCA
KLHL2
CUL3
KLHL2-005
ENST00000506761
ca1e32b0-7daf-403e-a3b2-7cfd3948cedf
Uterus.Uterus-AdenoCA
KLHL2
KLHL12
KLHL2-005
ENST00000506761
ca1e32b0-7daf-403e-a3b2-7cfd3948cedf
Uterus.Uterus-AdenoCA
KLHL2
CUL3
KLHL2-005
ENST00000506761
Interaction losses with Clinvar proteins
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Gene Name
CUL3